Results 11 to 20 of about 235,488 (257)

Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]

, 2015
Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh, Eva Saar, Jennifer Pilgrim, Louisa Degenhardt, Lucinda Burns, Suzanne Nielsen, Wayne D Hall   +6 more
core   +1 more source

Toxicological Study Employing Repeated Doses of Garcinielliptone FC, a Polyisoprenylated-Benzophenone Isolated from Seed of Platonia Insignis Mart [PDF]

, 2015
The major constituent from the hexane extract of the seeds of P. insignis is GFC (garcinielliptone FC). Doses of 25, 50and 75 mg/kg of GFC were aseptically suspended in 0.05% Tween 80 dissolved in 0.9% saline (vehicle) and orally administered for30, 90 ...
da Costa Júnior, Joaquim S., David, Jorge M., Faillace, Martín Sebastián, Falcão Ferraz, Alexandre de B., Filho, José Carlos C. L. S., Freitas, Rivelilson M., Peláez, Walter José, Silva, Ana P.   +7 more
core   +1 more source

TOXICITY OF PREDNISOLONE, DEXAMETHASONE AND THEIR PHOTOCHEMICAL DERIVATIVES ON AQUATIC ORGANISMS [PDF]

, 2004
Light exposure of aqueous suspensions of prednisolone and dexamethasone causes their partial phototransformation. The photoproducts, isolated by chromatographic techniques, have been identified by spectroscopic means.
DELLA GRECA, MARINA, FIORENTINO, ANTONIO, ISIDORI M., LAVORGNA M., PREVITERA, LUCIO, RUBINO M., TEMUSSI, FABIO   +6 more
core   +1 more source

Sub-chronic toxicity study in rats orally exposed to nanostructured silica [PDF]

Particle and Fibre Toxicology, 2014
Synthetic Amorphous Silica (SAS) is commonly used in food and drugs. Recently, a consumer intake of silica from food was estimated at 9.4 mg/kg bw/day, of which 1.8 mg/kg bw/day was estimated to be in the nano-size range. Food products containing SAS have been shown to contain silica in the nanometer size range (i.e.
van der Zande, M., Vandebriel, R.J., Groot, M.J., Kramer, E.H.M., Herrera Riviera, Z.E., Rasmussen, K., Ossenkoppele, J.S., Tromp, P., Gremmer, E.R., Peters, R.J.B., Hendriksen, P.J., Marvin, H.J.P., Hoogenboom, L.A.P., Peijnenburg, A.A.C.M., Bouwmeester, H.   +14 more
openaire   +5 more sources

A comparison of the results from intra-pleural and intra-peritoneal studies with those from inhalation and intratracheal tests for the assessment of pulmonary responses to inhalable dusts and fibres. [PDF]

, 2016
The aim of this paper is to compare results from inhalation studies with those from intraperitoneal and intrapleural tests, where available, for a number of fibrous and particulate test materials.
Bevan, Ruth, Drummond, Gail, Harrison, Paul   +2 more
core   +2 more sources

Superoxide Dismutase (SOD)-mimetic M40403 is protective in cell and fly models of paraquat toxicity: Implications for Parkinson disease [PDF]

, 2016
Parkinson disease is a debilitating and incurable neurodegenerative disorder affecting 3c1-2% of people over 65 years of age. Oxidative damage is considered to play a central role in the progression of Parkinson disease and strong evidence links chronic
Beltramini, Mariano, Bisaglia, Marco, Bubacco, Luigi, Casella, Luigi, Ferrari, Emanuele, Filograna, Roberta, Godena, Vinay K., Sanchez Martinez, Alvaro, Whitworth, Alexander J.   +8 more
core   +1 more source

Adverse reactions of amiodarone [PDF]

, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo, Ciacciarelli, Marco, Colunga Biancatelli, Ruben Ml, Congedo, Viviana, Iuliano, Luigi, Polidoro, Alessandro   +5 more
core   +1 more source

Benzotriazole is antiestrogenic in vitro but not in vivo [PDF]

, 2007
Copyright © 2007 SETAC. This is the accepted version of the following article: Harris et al (2007), "Benzotriazole is antiestrogenic in vitro but not in vivo", Environmental Toxicology and Chemistry, 26(11), 2367–2372, which has been published in final ...
Brian, JV, Giger, W, Harris, CA, Routledge, EJ, Schaffner, C, Sumpter, JP   +5 more
core   +1 more source

The ecological impact of different mechanisms of chronic sub-lethal toxicity on feeding and respiratory physiology [PDF]

, 1994
Sub-lethal toxicity tests, such as the scope-for-growth test, reveal simple relationships between measures of contaminant concentration and effect on respiratory and feeding physiology.
Willows, R.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source