Results 221 to 230 of about 235,488 (257)

Repeated sub-chronic oral toxicity study of xylooligosaccharides (XOS) in dogs

Regulatory Toxicology and Pharmacology, 2017
In this study, Beagle dogs were administered xylooligosaccharide (XOS, CAS # 87099-0) at doses of 0, 1250, 2500, and 5000 mg/kg/day by oral gavage for 26 weeks. A 4-week recovery period was added to observe delayed or reversible toxicity. Measurements included body weight, food consumption, clinical observations, temperature, electrocardiogram (ECG ...
Yonglin, Gao, Yunzhi, Wang, Yanshen, Li, Rui, Han, Chunmei, Li, Lin, Xiao, Susan, Cho, Yukui, Ma, Chao, Fang, Albert W, Lee   +9 more
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Acute and sub-chronic toxicity of four cytostatic drugs in zebrafish

Environmental Science and Pollution Research, 2015
The acute and sub-chronic effects of four cytostatic drugs-5-fluorouracil (5-FU), cisplatin (CisPt), etoposide (ET) and imatinib mesylate (IM)-on zebrafish (Danio rerio) were investigated. Acute tests were carried out in a static system in accordance with the OECD guideline 203 for adult fish and the draft guideline for fish embryos (FET test) in order
Róbert Kovács, Katalin Bakos, Béla Urbányi, Judit Kövesi, Gyöngyi Gazsi, Andrea Csepeli, Ádám János Appl, Dóra Bencsik, Zsolt Csenki, Ákos Horváth   +9 more
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Acute and Sub-Chronic Toxicity ofD-Allose in Rats

Bioscience, Biotechnology, and Biochemistry, 2010
We examined the acute and sub-chronic toxicity of D-allose in rats. In the acute toxicity test, the calculated LD(50) value was 20.5 g/kg. In the sub-chronic toxicity test, no difference was found among the four groups in most of the serum chemical and hematological test results. These results suggest that D-allose is not toxic to rats.
Yusuke, Iga, Kazunori, Nakamichi, Yoko, Shirai, Tatsuhiro, Matsuo   +3 more
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Acute toxicity and sub-chronic toxicity of steroidal saponins from Dioscorea zingiberensis C.H.Wright in rodents

Journal of Ethnopharmacology, 2009
Steroidal saponins from Dioscorea zingiberensis are widely used in China for curing cardiovascular diseases. However, there was little toxicological information available on them.The study evaluated potential toxicity of the steroidal saponins and analyzed the metabolites in rats.For the acute study, the steroidal saponins were administered to kunming ...
Yuan, Qin, Xiaohua, Wu, Wen, Huang, Guohua, Gong, Dan, Li, Yang, He, Yinlan, Zhao   +6 more
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Toxicity assessment due to sub-chronic exposure to individual and mixtures of four toxic heavy metals

Journal of Hazardous Materials, 2015
Humans are exposed to a cocktail of heavy metal toxicants in the environment. Though heavy metals are deleterious, there is a paucity of information on toxicity of low dose mixtures. In this study, lead (Pb) (0.01mg/L), mercury (Hg) (0.001mg/L), cadmium (Cd) (0.005mg/L) and arsenic (As) (0.01mg/L) were administered individually and as mixtures to 10 ...
Samuel J, Cobbina, Yao, Chen, Zhaoxiang, Zhou, Xueshan, Wu, Ting, Zhao, Zhen, Zhang, Weiwei, Feng, Wei, Wang, Qian, Li, Xiangyang, Wu, Liuqing, Yang   +10 more
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Pathology of sub-chronic cadmium and chlorpyrifos toxicity in broilers

Indian Journal of Veterinary Pathology, 2016
The present study was conducted to evaluate the toxic effects of cadmium and chlorpyrifos and their interaction on liver and kidney of broiler chicken. Twenty four birds were divided into four groups. Group-I was kept as control. Group-II, III and IV birds were administered with cadmium (50 mg/L in drinking water), chlorpyrifos (4 mg/kg body weight ...
R. Singh, A.K. Srivastava, N.K. Gangwar, D.K. Giri, Renu Singh, Rahul Kumar   +5 more
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Sub‐acute versus sub‐chronic oral toxicity study in rats: Comparative study of 82 compounds

Journal of Applied Toxicology, 1984
AbstractToxicity data of 82 compounds, tested in both a sub‐acute and a sub‐chronic study, were evaluated to find out whether it is possible to substitute a sub‐acute for a sub‐chronic study without losing quantitative information. The no‐effect level (NEL) and the minimal‐effect level (MEL) were used as the basis for comparison.
R A, Woutersen, H P, Til, V J, Feron
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Sub-chronic Toxicity of Defoamer Used in Seawater Desalination.

Biomedical and environmental sciences : BES, 2019
To explore the possible long-term health effects of the defoamer used in seawater desalination by sub-chronic toxicity testing.Blood analysis, internal organ assessment, and histopathological examination were carried out in rats exposed to low, medium, and high (0.5, 1.0, and 2.0 g/kg BW, respectively) doses of defoamer for 90 days through oral ...
Lian, Duan, Chong Hua, Zhang, Wen, Gu, Hong, Zhi, Jian, Kong, Shao Ping, Zhang, Yi Min, Li, Kai, Lu   +7 more
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The Sub-acute and Chronic Toxicity of 1,1-Dimethylhydrazine Vapor

American Industrial Hygiene Association Journal, 1960
(1960). The Sub-acute and Chronic Toxicity of 1,1-Dimethylhydrazine Vapor. American Industrial Hygiene Association Journal: Vol. 21, No. 3, pp. 207-210.
W E, RINEHART, E, DONATI, E A, GREENE
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Acute and (sub)chronic toxicity of the neonicotinoid imidacloprid on Chironomus riparius

Chemosphere, 2018
Impacts of neonicotinoids on non-target insects, including aquatic species, may significantly influence ecosystem structure and functioning. The present study investigated the sensitivity of Chironomus riparius to imidacloprid exposures during 24-h, 10- and 28-days by assessing larval survival, growth, emergence and oxidative stress-related parameters.
Naveen Njattuvetty Chandran, Dana Fojtova, Lucie Blahova, Eliska Rozmankova, Ludek Blaha   +4 more
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