Results 11 to 20 of about 24,424 (216)

Phytochemical composition, acute and subacute toxicity profile of Persea amaricana seed oil in albino Wistar rats [PDF]

Toxicology Reports
Objective: This study investigated the phytochemical composition and toxicity profile of Persea americana seed oil (PASO) in albino Wistar rats. Methods: Chromatography-mass spectrometry (GC-MS) was used to analyse the chemical constituents of PASO.
Emeka Joshua Iweala, Finian Uchenna Okore, Benedict Chukwuebuka Okoro, Omoremime Elizabeth Dania, Doris Nnenna Amuji, Eziuche Amadike Ugbogu   +5 more
doaj   +2 more sources

Repeated Systemic Toxicity Tests: A Call for Proper Understanding of Tests Durations Nomenclature [PDF]

Asia Pacific Journal of Medical Toxicology, 2022
Background: Testing of substances such as drugs, food, cosmetics, and chemicals meant for human utilization requires necessary guidelines to be followed.
Earnest Erhirhie, Goodies Moke
doaj   +1 more source

Investigation of Chemical Composition of Oriental plane (Platanus orientalis L.) Hydrosol and its Effects on Tissue Damage Markers and Plasma Enzymes in Short-term Consumption [PDF]

Trends in Pharmaceutical Sciences, 2020
Oriental plane hydrosol (distillate), as a remedy for weight gain and asthma treatment is popular in ethnomedicine. Phytochemicals of medicinal plants could have side effects or serious damages.
Reza Heidari, Akbar Raeisi, Ardalan Pasdaran, Azadeh Hamedi   +3 more
doaj   +1 more source

The subacute toxicity of 1,1-dimethylhydrazine [PDF]

Toxicology and Applied Pharmacology, 1969
Abstract Daily injections of 70, 50, 30, or 10 mg UDMH/kg resulted in the death of 9, 6, 5, and 0 rats, respectively, in each group of 10. All deaths occurred within the first 3 days. Animals surviving the first 3 days began to gain weight even though daily dosing was continued.
Cornish, Herbert H., Hartung, Rolf
openaire   +3 more sources

Phytochemical component and toxicological evaluation of purple sweet potato leaf extract in male Sprague–Dawley rats

Frontiers in Pharmacology, 2023
This study assessed the toxicity of lutein-rich purple sweet potato leaf (PSPL) extract in male Sprague–Dawley rats.Methods and study design: A total of 54 adult male Sprague–Dawley rats were used.
Ahmad Safiyyu’d-din Bin Hisamuddin, Ahmad Safiyyu’d-din Bin Hisamuddin, Ruth Naomi, Ruth Naomi, Khairul Aiman Bin Manan, Hasnah Bahari, Muhammad Dain Yazid, Fezah Othman, Hashim Embong, Siti Hadizah Jumidil, Mohd Khairi Hussain, Zainul Amiruddin Zakaria   +11 more
doaj   +1 more source

Phytochemical Identification, Acute, and Sub-Acute Oral Toxicity Studies of the Foliar Extract of Withania frutescens

Molecules, 2020
Withania frutescens (W. frutescens) is a medicinal plant widely used to treat several diseases. This work aims to study phytochemical composition as well as acute and subacute toxicity of W. frutescens hydroethanolic extract in mice.
Abdelfattah EL Moussaoui, Mohammed Bourhia, Fatima Zahra Jawhari, Hamza Mechchate, Meryem Slighoua, Ahmed Bari, Riaz Ullah, Hafiz Majid Mahmood, Syed Saeed Ali, Samir Ibenmoussa, Dalila Bousta, Amina Bari   +11 more
doaj   +1 more source

Phytochemical and toxicological evaluation of Zephyranthes citrina

Frontiers in Pharmacology, 2022
Drugs obtained from medicinal plants have always played a pivotal role in the field of medicine and to identify novel compounds. Safety profiling of plant extracts is of utmost importance during the discovery of new biologically active compounds and the ...
Muhammad Haseeb Ur Rehman, Uzma Saleem, Bashir Ahmad, Memoona Rashid   +3 more
doaj   +1 more source

Subacute toxicity of ricazol as injection

Российский паразитологический журнал, 2016
Subacute toxicity of Ricazol as injection, containing in 1 ml 100 mg Rico-bendazole is studied. The preparation in doses of 125 and 50 mg/kg at daily intro-duction during 7 days didn't cause deviations in behavior, consumption of forage and water ...
E. V. Abramova, I. A. Arkhipov, A. V. Balyshev, E. V. Glukhareva, S. V. Novikova   +4 more
doaj   +1 more source

The Study on Acute·Subacute Toxicity of Juglandis Semen Herbal-acupuncture(JsD).

Journal of Pharmacopuncture, 2001
Objective: This study was purposed to investigate the acute·subacute toxicity of Herbal acupuncture with Juglandis Semen(JsD) in mice and rats. Methods: Balb/c mice were injected intraperitoneally with JsD for LD50 and acute toxicity test.
Kang Kye-Sung, Kwon Gi Rok
doaj   +1 more source

The Study on Acute and Subacute Toxicity and Sarcoma-180 Anti-cancer Effects of Armeniacae amarum semen Herbal-Acupuncture(Haeng-In)

Journal of Pharmacopuncture, 2002
Objective: The purpose of this study was to investigate acute and subacute toxicity and sarcoma-180 anti-cancer effects of Herbal acupuncture with Anneniacae amarum semen (Haeng-in) in mice and rats.
Ok, Kim , Ki-Rok, Kwon
doaj   +1 more source