Results 31 to 40 of about 24,424 (216)

Study of PEG-Filstim sub-acute toxicity

Фармацевтичний журнал, 2018
Febrile neutropenia caused by cytostatic therapy in the treatment of oncological diseases is a frequent complication, which results in enforced reduction in chemotherapy doses and lower effectiveness of the treatment.
V. L. Karbovskyi, I. A. Shevchuk, O. V. Kurkina, T. Ye. Makovska   +3 more
doaj   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

The Study on Acute and Subacute Toxicity and Anti-Cancer Effects of cultivated wild ginseng Herbal acupuncture

Journal of Pharmacopuncture, 2003
Objectives : The purpose of this study was to investigate acute and subacute toxicity and sarcoma-180 anti-cancer effects of herbal acupuncture with cultivated wild ginseng (distilled) in mice and rats.
Ki-Rok, Kwon, A-La, Cho, Sun-Gu, Lee
doaj   +1 more source

Subacute toxicity of isoliquiritigenin-zein phosphatidylcholine nanoparticles on biochemical, hematological, and histopathological parameters in Sprague-Dawley rats [PDF]

Exploration of Drug Science
Aim: Isoliquiritigenin (ISL) is a natural flavonoid found in many natural plants, which exhibits numerous pharmacological properties including anti-inflammatory, antioxidant, antitumor, and antiviral activities.
Ke Yang, Kumar Ganesan, Fei Gao, Chunguang Xie, Jianping Chen   +4 more
doaj   +1 more source

Subacute and Chronic Toxicities of Ascorbyl Palmitates

Experimental Biology and Medicine, 1946
SummaryWhen l-ascorbyl palmitate and d-isoascorbyl palmitate were fed subacutely for 9 months in concentrations of 2% and 5% of the diet, only the 5% levels were toxic. The growth rates of rats on the 5% levels were significantly retarded and bladder stones were produced in 2 animals on the 5% 1-ascorbyl palmitate. d-Isoascorbie acid in a concentration
O G, FITZHUGH, A A, NELSON
openaire   +2 more sources

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Phytochemical Profiling and Toxicity Assessment of Aqueous Extract From Bitter Apricot Kernels Cultivated in Morocco

Scientifica
Apricot kernels contain amygdalin, a cyanogenic glycoside that degrades to cyanide upon chewing or crushing, posing a potential toxicity risk to humans.
Mohamed Amine El-Hajjaji, Ghizlane Nouioura, Kawtar Fikri-Benbrahim, Najoua Soulo, Mohammed El Ouassete, Badiaa Lyoussi, Zineb Benziane Ouaritini   +6 more
doaj   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Toxicological Study of Ocimum sanctum Linn Leaves: Hematological, Biochemical, and Histopathological Studies

Journal of Toxicology, 2014
The present study was aimed to study the acute and subacute toxicity studies with orally administered 50% ethanolic leaves extract of Ocimum sanctum Linn (OSE).
M. K. Gautam, R. K. Goel
doaj   +1 more source

Sunscreen‐Inspired Nano‐Pesticide for UV‐Shielding and Laccase‐Responsive Delivery of Mancozeb With Enhanced Fungicidal Efficacy and Ecological Safety

Advanced Science, EarlyView.
The sunscreen‐inspired nano‐pesticide, MCB@URFSL, provides UV‐shielding, enhanced rainfastness, and laccase‐responsive delivery for improved fungicidal efficacy and high ecological safety. ABSTRACT Fungicides are a crucial tool for protecting crops and ensuring consistent food supply.
Jin Yan, Xin Ye, Linping He, Cheng Hong, Xu‐Huan Zhao, Gizachew Mulugeta Manahelohe, Xiao‐Tong Feng, Yu‐Cheng Gu, Qiang Bian, Min Wu, Ming‐Zhi Zhang   +10 more
wiley   +1 more source