Results 81 to 90 of about 604,007 (352)

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

Commentary [Decompressive craniectomy in patients with cerebral infarction due to malignant vasospasm after aneurysmal subarachnoid hemorrhage] [PDF]

, 2012
Commentary: article "Decompressive craniectomy in patients with cerebral infarction due to malignant vasospasm after aneurysmal subarachnoid hemorrhage" on page 251 http://www.ncbi.nlm.nih.gov/pmc/articles ...
Archavlis, Eleftherios
core  

Brain macrophages in human cortical contusions as indicator of survival period [PDF]

, 1986
The aim of this study was to establish a morphologic time scheme with which cases of cerebral contusion with unknown survival periods can be dated. Our study of 275 cases was limited to qualitative and quantitative changes in macrophages.
Adams, Adams, Adrian, Baggenstoss, Carmichael, Clopper, del Rio-Hortega, Edelmann, Eisenmenger, Gedigk, Gedigk, Gerhard Berghaus, Gerhard Raff, Hallermann, Hammes, Howarth, Jacob, Kennady, Konigsmark, Krauland, Környey, Link, Manfred Oehmichen, Meesen, Müller, Oehmichen, Oehmichen, Oehmichen, Oehmichen, Russell, Sachs, Schröder, Schröder, Schröder, Spielmeyer, Strassmann, Wolfgang Eisenmenger   +36 more
core   +1 more source

Hydrocephalus after Subarachnoid Hemorrhage: Pathophysiology, Diagnosis, and Treatment

BioMed Research International, 2017
Hydrocephalus (HCP) is a common complication in patients with subarachnoid hemorrhage. In this review, we summarize the advanced research on HCP and discuss the understanding of the molecular originators of HCP and the development of diagnoses and ...
Sheng Chen, Jinqi Luo, C. Reis, A. Manaenko, Jianmin Zhang   +4 more
semanticscholar   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Subarachnoid Hemorrhage after Surgery of the Medulla Oblongata Hemangioblastoma: A Case Report

Brain Science Advances, 2016
Objectives To discuss the bleeding mechanisms after removing a medulla oblongata hemangioblastoma. Methods A 42-year-old male patient was diagnosed with a medulla oblongata hemangioblastoma.
Xiang Yang, Yuekang Zhang, Xuesong Liu, Maojun Chen   +3 more
doaj   +1 more source

Persistent primitive hypoglossal artery presenting with perimesencephalic nonaneurysmal subarachnoid hemorrhage: A case report and review of literature

Interdisciplinary Neurosurgery, 2020
Background: Persistent primitive hypoglossal artery (PPHA) is a rare remnant of the congenital carotid-basilar artery anastomosis, sometimes associated with subarachnoid hemorrhage (SAH), and aneurysms are the more common cause.
Hui Shen, Qing Mei, Junyan Shen, Fuzheng Zhang   +3 more
doaj   +1 more source

Contribution of Matrix Metalloproteinase-9 to Cerebral Edema and Functional Outcome following Experimental Subarachnoid Hemorrhage [PDF]

, 2011
Background: Cerebral edema is an important risk factor for death and poor outcome following subarachnoid hemorrhage (SAH). However, underlying mechanisms are still poorly understood.
Bauer AT, Broderick JP, Burggraf D, Claassen J, Clark AW, Doczi T, Dzwonek J, Feiler S, Fukuda S, Gasche Y, Guo Z, Jadhav V, Karsten Schöller, Mandal M, Mun-Bryce S, Nikolaus Plesnila, Rosenberg GA, Rosenberg GA, Rosenberg GA, Rosenberg GA, Schöller K, Sehba FA, Serge C. Thal, Sergej Feiler, Stanley JR, Stefan Zausinger, Thal SC, Vu TH, Wang X, Zausinger S   +29 more
core   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Pseudo-subarachnoid hemorrhage

The American Journal of Emergency Medicine, 2008
The computed tomographic (CT) finding of pseudo-subarachnoid hemorrhage (SAH) mimics that of SAH. In brain swelling due to acute hypoxic anoxic encephalopathy, the increased attenuation in the basal cisterns and subarachnoid spaces on CT scans is a characteristic finding of acute SAH.
Je Sung, You, Saehwan, Park, Yoo Seok, Park, Sung Pil, Chung   +3 more
openaire   +3 more sources