Results 1 to 10 of about 9,626,298 (215)

Genomic and antigenic evolution of influenza A(H3N2) after the COVID-19 era: a scoping review with focus on J and K subclades and implications for vaccine effectiveness

Germs
The objective of this scoping review is to systematically map and synthesize the available evidence on the post-pandemic genomic and antigenic evolution of influenza A(H3N2), with particular focus on emerging antigenic drift variants, including those later designated as subclade K (J.2.4.1), and their implications for vaccine effectiveness and public ...
Angelo Cianciulli, Emanuela Santoro, Salvatore Esposito, Savino Quaglierella, Antonietta Pacifico, Michele Nappa, Domenico Fornino, Roberta Manente, Mario Capunzo, Giovanni Boccia   +9 more
core   +3 more sources

Outpatients’ interim estimates of 2025–2026 seasonal influenza vaccine effectiveness in the Community of Madrid (SiVIRA-MAD Group Data)

Vaccine: X
Background: In June and July 2025, a rapid increase in the incidence of influenza A(H3N2) subclade K raised awareness about a possible vaccine mismatch.
Macarena Garrido-Estepa, Luis García-Comas, Mercedes Rumayor-Zarzuelo, Juan Carlos Sanz-Moreno, Ana Garrido-Buenache, Susana Jiménez-Bueno, Rodrigo Martínez-Arce, Marta Huerta-Cofiño, Alba Nieto-Julia, María Araceli Arce-Arnáez   +9 more
doaj   +1 more source

Genomic, antigenic and transmission dynamics of influenza A(H3N2) subclade K in Canada, early 2025/26 season

Abstract Influenza A(H3N2) subclade K virus was detected in Canada early in the 2025/26 influenza season, bearing an antigenic transition in the hemagglutinin (HA) glycoprotein. Analysis of 396 HA sequences from Canada showed antigenic divergence from 2025/26 influenza vaccine strains, consistent with partial mismatch.
George S. Long, Thomas W.A. Braukmann, Nicholas Waglechner, Patryk Aftanas, Alex Marchand-Austin, Julianne V. Kus, Shawn T. Clark, Kevin Katz, Maan Hasso, Finlay Maguire, Samir N. Patel, Samira Mubareka, Venkata R. Duvvuri   +12 more
openaire   +1 more source

A Novel Mastadenovirus from Nyctalus noctula Which Represents a Distinct Evolutionary Branch of Viruses from Bats in Europe

Viruses
Bats are natural hosts of a wide variety of viruses, including adenoviruses. European bats are known to carry mastadenoviruses categorized as species B (widespread in European Vespertilionidae bats) and whose taxonomy has not been clarified.
Anna S. Speranskaya, Alexander V. Dorokhin, Elena V. Korneenko, Ivan K. Chudinov, Andrei E. Samoilov, Sergei V. Kruskop   +5 more
doaj   +1 more source

Recent emergence of cephalosporin-resistant Salmonella Typhi in India due to the endemic clone acquiring IncFIB(K) plasmid encoding blaCTX-M-15 gene

Microbiology Spectrum
The emergence and spread of Salmonella Typhi (S. Typhi) resistant to third-generation cephalosporins is a serious global health concern. In this study, we genomically characterized 142 cephalosporin-resistant S.
Tharani Priya Thirumoorthy, Jobin John Jacob, Aravind Velmurugan, Monisha Priya Teekaraman, Bhavini Shah, Veena Iyer, Geeti Maheshwari, Urmi Trivedi, Anand Shah, Pooja Patel, Anushree Gaigawale, Yesudoss M, Pavithra Sathya Narayanan, Ankur Mutreja, Megan Carey, Jacob John, Gagandeep Kang, Balaji Veeraraghavan   +17 more
doaj   +1 more source

Bacteremic Group A Streptococcal Co-Infection in Two Adults with H3N2 Influenza in Japan, 2025–2026: A Case Series

International Medical Case Reports Journal
Masafumi SekiDivision of Infectious Diseases and Infection Control, Saitama Medical University International Medical Center, Hidaka City, Saitama, JapanCorrespondence: Masafumi Seki, Division of Infectious Diseases and Infection Control, Saitama Medical ...
Seki M
doaj  

Genetic Diversity and Population Structure of Hainan Indigenous Pig Breeds Revealed by Microsatellite and mtDNA D-Loop Analysis

Animals
This study investigated the genetic diversity and population structure of five Hainan indigenous pig breeds (147 individuals from 7 populations representing 5 breeds: 3 Duntou pig subpopulations (DT-DZ, DT-SJ, and DT-SG) and four additional breeds ...
Yushan Cui, Maosong Wu, Xiaolei Ding, Jiayu Yan, Jing Chen, Shidao Zhao, Lifan Zhang, Wei Wei, Jie Chen   +8 more
doaj   +1 more source

Transition from Quadrivalent to Trivalent Influenza Vaccination Compared with Continued Quadrivalent Vaccination for Preventing Severe Influenza Outcomes in Populations in Indonesia: Implications from the 2025–2026 Epidemiological Landscape

Acta Medica Indonesiana
Seasonal influenza remains a global public health challenge, with an estimated 1 billion infections and 290,000-650,000 respiratory deaths each year.
Sukamto Koesnoe, Cissy Kartasasmita
doaj   +2 more sources

Genomic dissection of the clonal background and global dissemination of hypervirulent Klebsiella pneumoniae CG23-KL57 lineage

Nature Communications
The emergence of multidrug-resistant and hypervirulent Klebsiella pneumoniae represents a growing threat to global public health. Here we investigate the genomic epidemiology and evolutionary dynamics of emerging K.
Shuangshuang Li, Yawen Yu, Siqi Liu, Menglu Zhang, Guoli Li, Qian Tong, Qingyang Sun, Huiqiong Jia, Zhiyu Wang, Yingying Kong, Yingying Zhang, João Pedro Rueda Furlan, Mohamed S. Draz, Ning Dong, Yongchang Xu, Zhi Ruan   +15 more
doaj   +1 more source

CIST: A clade-informed sequence transformer framework for predicting influenza virus antigenicity

Scientific Reports
Rapid antigenic evolution of influenza viruses complicates timely vaccine strain selection and renders prospective interpretation of serological assays—including neutralization (NT) and hemagglutination inhibition (HI)—increasingly challenging in the ...
Kang Hu, Yongshan Zhu, Qingchuan Zhang, Jian Li   +3 more
doaj   +1 more source