Results 21 to 30 of about 9,028,692 (199)

Vaccine-Elicited Antibody Responses to Influenza A(H3N2) Subclade K.

open access: yesJAMA
Abstract Influenza H3N2 subclade K (J.2.4.1) is a genetic branch of H3N2 with 11 mutations in hemagglutinin and currently represents the dominant circulating influenza strain. We evaluated antibody responses to H3N2 subclade K before and after influenza vaccination in 46 healthy individuals.
Wang L   +16 more
europepmc   +3 more sources

Loss of hemagglutination ability by H3N2 influenza A virus, subclade K

open access: yes
Abstract Seasonal human H3N2 influenza viruses, subclade K (J.2.4.1), have been the predominant influenza A viruses in the Northern hemisphere influenza season of 2025/2026. Since 2024, the vaccine virus A/Darwin/6/21 has emerged in different antigenic variants.
Ruonan Liang   +8 more
openaire   +2 more sources

P-60 - THE ‘SUPER FLU’ THAT WASN’T: THE IMPACT OF THE H3N2 SUBCLADE K ON THE SCOTTISH POPULATION, 2025/26 [PDF]

open access: yesJ Public Health (Oxf)
Abstract Background Seasonal influenza remains unpredictable due to continual viral evolution, particularly within A(H3N2) lineages. Novel subclades can alter transmission, severity, and vaccine effectiveness (VE), underscoring the importance of pathogen-specific surveillance.
Mr Ebrahim Makhoul   +8 more
europepmc   +2 more sources

Subclade K influenza A (H3N2) viruses display partial immune escape with preserved cross-neutralisation in a UK population

open access: yes
ABSTRACT We examined whether the recent emergence of influenza A(H3N2) subclade K, associated with an unusually early influenza season in the Northern hemisphere, was accompanied by a reduction in human population immunity. Using virus neutralisation assays on pre-epidemic human sera collected in May 2025, we found evidence of moderate ...
Dee K   +19 more
europepmc   +2 more sources

Influenza vaccine effectiveness in school outbreaks during a A(H3N2) subclade K (J.2.4.1)-dominated season in Beijing, China, 2025-26

open access: yesInternational Journal of Infectious Diseases
: Objectives: Schools are high-risk settings for influenza transmission. During the 2025-26 Northern Hemisphere season, influenza A(H3N2) subclade K (J.2.4.1) rapidly emerged and became predominant, but vaccine effectiveness (VE) in school-associated ...
Ying Shen   +20 more
doaj   +2 more sources

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