Antiviral Resistance Associated With Multiple Mutations Occurring in Seasonal Influenza A(H3N2) Virus in a Patient Treated With Oseltamivir. [PDF]
ABSTRACT Our case highlights the importance of early diagnosis in respiratory illness and timely detection of drug resistance so that antiviral treatment can be initiated and modified, particularly for high‐risk groups. Vaccination and early, carefully dosed antiviral treatment are key to mitigating severe influenza cases, especially in ...
Hussain S +9 more
europepmc +2 more sources
Influenza Vaccine Effectiveness Against Mild and Severe Outcomes: A Comparison Study in Portugal. [PDF]
ABSTRACT Background Influenza vaccination is an effective public health intervention to lessen influenza effect on healthcare and has been recommended to prevent severe outcomes. Previous studies present higher influenza vaccine effectiveness (IVE) estimates against primary care medically attended (outpatients) compared to hospitalised cases ...
Mourao F +5 more
europepmc +2 more sources
Community Incidence of Influenza Virus Infections During Postpandemic Seasons in China, 2022–2025: A Serial Prospective Cohort Study [PDF]
ABSTRACT Background Following unprecedented disruption of influenza circulation during COVID‐19, concerns arose about postpandemic immunity debt. Community influenza epidemiological and burden data are scarce in mainland China. We estimated influenza incidence in Yancheng (2022–2025) and evaluated protection conferred by preexisting antibodies ...
Zhang H +23 more
europepmc +2 more sources
Influenza Vaccination Effectiveness in Preventing Hospitalization of Adults With Underlying Medical Conditions: A Multicentre Case-Control Study. [PDF]
ABSTRACT Background Seasonal influenza, especially in persons with underlying medical conditions, is a substantial global burden. Influenza vaccination effectiveness (VE) varies annually, requiring continuous evaluation due to evolving viruses and vaccination coverages. Our aim was to investigate influenza VE in preventing hospitalization for confirmed
Toledo D +12 more
europepmc +2 more sources
Prior immunity to seasonal influenza A(H3N2) virus confers varying levels of cross-protection against challenge with clade 2.3.4.4b A(H5N1), A(H7N9), or A(H9N2) virus in a ferret model [PDF]
Evaluating how prior immunity to seasonal influenza viruses influences subsequent zoonotic influenza A virus (IAV) infection in animal models is critical for pandemic preparedness.
Xiangjie Sun +15 more
doaj +2 more sources
Avian-to-mammal transmission and mammalian adaptation of avian influenza virus (AIV) are threats to public health and of great concern. The H3 subtype of influenza virus has low pathogenicity and is widely distributed in humans, canines, equines and ...
Qiucheng Yao +7 more
doaj +1 more source
Estimating Influenza-associated Mortality in Korea: The 2009-2016 Seasons [PDF]
Objectives Estimating influenza-associated mortality is important since seasonal influenza affects persons of all ages, causing severe illness or death.
Kwan Hong, Sangho Sohn, Byung Chul Chun
doaj +1 more source
Evaluation of Next-Generation H3 Influenza Vaccines in Ferrets Pre-Immune to Historical H3N2 Viruses
Each person has a unique immune history to past influenza virus infections. Exposure to influenza viruses early in life establishes memory B cell populations that influence future immune responses to influenza vaccination.
James D. Allen, Ted M. Ross, Ted M. Ross
doaj +1 more source
Phylogenetic Analysis of HA and NA Genes of Swine Influenza Viruses in Serbia in 2016-2018
Pigs are very important for the epidemiology of influenza A viruses, being commonly infected with the lineages of most adapted H1N1, H3N2, H1N2 swine subtypes.
Maksimović Zorić Jelena +9 more
doaj +1 more source
Generation of a Reassortant Influenza A Subtype H3N2 Virus Expressing Gaussia Luciferase
Reporter influenza A viruses (IAVs) carrying fluorescent or luminescent genes provide a powerful tool for both basic and translational research. Most reporter IAVs are based on the backbone of either subtype H1N1 viruses, A/Puerto Rico/8/1934 (PR8) or A ...
Lin Wang +6 more
doaj +1 more source

