Results 31 to 40 of about 18,035 (133)

Clinical and socioeconomic impact of different types and subtypes of seasonal influenza viruses in children during influenza seasons 2007/2008 and 2008/2009

BMC Infectious Diseases, 2011
Background There are few and debated data regarding possible differences in the clinical presentations of influenza A/H1N1, A/H3N2 and B viruses in children. This study evaluates the clinical presentation and socio-economic impact of laboratory-confirmed
Giacchino Raffaella, Bruzzese Eugenia, Cecinati Valerio, Da Dalt Liviana, Fossali Emilio, Valzano Antonia, Daleno Cristina, Molteni Claudio, Esposito Susanna, Giaquinto Carlo, Lackenby Angie, Principi Nicola   +11 more
doaj   +1 more source

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus‐Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System

PROTEOMICS, EarlyView.
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez, Melanie Dos Santos, Mikaël Attia, Killian De Geest, Ibrahim Hamid, Rodrigue Tesse, Ilham Fdillate, Marc Boschmans, Steven Van Borm, Mieke Steensels, Benedicte Lambrecht, Lionel Tafforeau, Caroline Demeret, Cyril Barbezange   +13 more
wiley   +1 more source

Targeting influenza A virus by splicing inhibitor herboxidiene reveals the importance of subtype-specific signatures around splice sites

Journal of Biomedical Science, 2023
Background The association between M segment splicing and pathogenicity remains ambiguous in human influenza A viruses. In this study, we aimed to investigate M splicing in various human influenza A viruses and characterize its physiological roles by ...
Yi-Ju Han, Kuo-Ming Lee, Guan-Hong Wu, Yu-Nong Gong, Avijit Dutta, Shin-Ru Shih   +5 more
doaj   +1 more source

Characterization of Canine Influenza Virus A (H3N2) Circulating in Dogs in China from 2016 to 2018

Viruses, 2021
Avian H3N2 influenza virus follows cross-host transmission and has spread among dogs in Asia since 2005. After 2015–2016, a new H3N2 subtype canine influenza epidemic occurred in dogs in North America and Asia.
Yuanguo Li, Xinghai Zhang, Yuxiu Liu, Ye Feng, Tiecheng Wang, Ye Ge, Yunyi Kong, Hongyu Sun, Haiyang Xiang, Bo Zhou, Shushan Fang, Qing Xia, Xinyu Hu, Weiyang Sun, Xuefeng Wang, Keyin Meng, Chaoxiang Lv, Entao Li, Xianzhu Xia, Hongbin He, Yuwei Gao, Ningyi Jin   +21 more
doaj   +1 more source

Recurring Temporal Association Between Influenza A Epidemics and Subsequent Influenza B Dominance in Post‐Pandemic Korea, 2022−2026

Journal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Post‐pandemic influenza dynamics have shown unusual patterns globally. We investigated the re‐emergence and recurrent seasonal dominance of influenza B in Korea across three post‐pandemic seasons (2022−2026). We analyzed 157 consecutive weeks of national sentinel surveillance data (K‐SenS, Korea Disease Control and Prevention Agency), covering
Yoon Lee, Yoonsun Yoon, Ji Eun Park, Won Keun Kim, Youn Young Choi, Yun‐Kyung Kim, Changmin Kang, Young Yoo, Young June Choe   +8 more
wiley   +1 more source

Antiviral activity of Siberian wild and cultivated plants

BIO Web of Conferences, 2020
The article presents data on the antiviral activity of ethanol and aqueous extracts isolated from the herb plants Dracocephalum nutans, Glechoma hederacea, Melissa officinalis, Berteroa incana, Aegopodium podagraria, and Veronica longifolia against the A/
Mazurkova Natalya, Protsenko Mariya, Lobanova Irina, Filippova Ekaterina, Vysochina Galina   +4 more
doaj   +1 more source

Anti‐idiotypic antibodies as molecular mimics of conserved influenza hemagglutinin epitopes

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Broadly neutralizing antibodies (bNAbs) provide insights for developing universal influenza vaccines through their ability to neutralize diverse viral strains. However, designing antigens that reliably elicit bNAb responses remains challenging due to the difficulty in targeting conserved epitopes with a single antigen.
Hiroshi Itou, Kaori Sano, Akira Ainai, Kazushige Otsuki, Toshikazu Inoue, Takuya Hemmi, Hideki Hasegawa, Tadaki Suzuki   +7 more
wiley   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Temporal patterns of influenza A subtypes and B lineages across age in a subtropical city, during pre-pandemic, pandemic, and post-pandemic seasons

BMC Infectious Diseases, 2019
Background Seasonal patterns of influenza A subtypes and B lineages in tropical/subtropical regions across age have remained to be explored. The impact of the 2009 H1N1 pandemic on seasonal influenza activity have not been well understood.
Linlin Zhou, Huiping Yang, Yu Kuang, Tianshu Li, Jianan Xu, Shuang Li, Ting Huang, Chuan Wang, Wanyi Li, Mingyuan Li, Shusen He, Ming Pan   +11 more
doaj   +1 more source