Results 51 to 60 of about 136,671,996 (217)

Estimating the impact of influenza vaccination and antigenic drift on influenza-related morbidity and mortality in England & Wales using hidden Markov models [PDF]

open access: yes
Influenza causes substantial morbidity and mortality in some influenza sea- sons, especially among the elderly. Influenza seasons dominated by circula- tion of influenza A/H3N2 virus tend to result in more morbidity and mor- tality than seasons ...
Mann, Andrea Gail
core   +1 more source

Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. [PDF]

open access: yes, 2011
Glycyrrhizin is known to exert antiviral and anti-inflammatory effects. Here, the effects of an approved parenteral glycyrrhizin preparation (Stronger Neo-Minophafen C) were investigated on highly pathogenic influenza A H5N1 virus replication, H5N1 ...
Michaelis, Martin   +20 more
core   +2 more sources

Antiviral activity of Siberian wild and cultivated plants

open access: yesBIO Web of Conferences, 2020
The article presents data on the antiviral activity of ethanol and aqueous extracts isolated from the herb plants Dracocephalum nutans, Glechoma hederacea, Melissa officinalis, Berteroa incana, Aegopodium podagraria, and Veronica longifolia against the A/
Mazurkova Natalya   +4 more
doaj   +1 more source

Temporal and Demographic Variations in Hospital‐Based Influenza A Virus Positivity Rates Before, During, and After the COVID‐19 Pandemic: A 6‐Year Single‐Center Study in Southwest China

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
ABSTRACT Objective To characterize the epidemiological dynamics of hospital‐based influenza A virus (IAV) test positivity rates (TPR) across the pre‐, during‐, and post‐COVID‐19 pandemic periods in Southwest China, while addressing biases introduced by evolving testing methodologies and healthcare‐seeking behaviors.
Hao Dang   +4 more
wiley   +1 more source

Mitochondria in Viral Infections: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Viral infections remodel mitochondrial function through direct viral regulation and infection‐induced changes in host cellular processes. These alterations affect OXPHOS, mitochondrial metabolism, calcium homeostasis, membrane potential, redox regulation, dynamics, and apoptosis, with distinct effects on viral replication and host antiviral responses ...
Ha Young Oh, Hye Jin Shin
wiley   +1 more source

Verification of the Combimatrix influenza detection assay for the detection of influenza A subtype during the 2007–2008 influenza season in Toronto, Canada

open access: yesVirology Journal, 2009
The increase in adamantine resistance in influenza A (H3N2) and the emergence of oseltamivir resistance in influenza A (H1N1) has necessitated the use of rapid methodologies to detect influenza subtype.
Blair Joanne   +5 more
doaj   +1 more source

A Mechanistic Viral Host Perturbation Score (VHPS) Reveals Shared and Virus‐Specific Transcriptional Programs Across Human Respiratory Infections

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 11, November 2026.
ABSTRACT Background Acute viral infections trigger overlapping but virus‐specific blood transcriptional responses; however, current analyses rarely quantify the mechanistic depth of activation across pathways, regulators, and immune cell compositions. Methods RNA‐seq data from GSE157240 were reanalyzed to infer transcription factor (TF) activity using ...
Sabri Saeed Sanabani
wiley   +1 more source

Temporal patterns of influenza A subtypes and B lineages across age in a subtropical city, during pre-pandemic, pandemic, and post-pandemic seasons

open access: yesBMC Infectious Diseases, 2019
Background Seasonal patterns of influenza A subtypes and B lineages in tropical/subtropical regions across age have remained to be explored. The impact of the 2009 H1N1 pandemic on seasonal influenza activity have not been well understood.
Linlin Zhou   +11 more
doaj   +1 more source

Surveillance of human influenza A (H3N2) virus from 1999 to 2009 in southern Italy

open access: yes, 2013
The aim of this study was to evaluate the presence of influenza virus co-infections in humans and changes in the genetic variability of A(H3N2) virus strains in southern Italy from 1999 to 2009.
Donatelli I   +19 more
core   +1 more source

Generation of replication-proficient Influenza Virus NS1 point mutants with interferon-hyperinducer phenotype [PDF]

open access: yes, 2014
The NS1 protein of influenza A viruses is the dedicated viral interferon (IFN)-antagonist. Viruses lacking NS1 protein expression cannot multiply in normal cells but are viable in cells deficient in their ability to produce or respond to IFN.
Fernández, Yolanda   +39 more
core   +2 more sources

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