Results 71 to 80 of about 136,671,996 (217)

Molecular epidemiological characterization of influenza A（H3N2） virus in Fengxian District， Shanghai， in the surveillance year of 2023

Shanghai yufang yixue
ObjectiveTo understand the epidemiological distribution and gene evolutionary variation of influenza A (H3N2) viruses in Fengxian District, Shanghai, in the surveillance year of 2023, and to provide a reference basis for influenza prevention and control ...
ZHAO Hongwei, TAO Lixin, XIE Xiaohong, HU Yi, ZHAO Xue, LIU Meihua, ZHANG Qingyuan, LU Lijie, LIU Chen’an, WU Mei   +9 more
doaj   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Column charts showing antibody titers against H1N1pdm09 subtype and H3N2 subtype influenza A virus NS1 proteins in serum specimens obtained from narcoleptic patients.

, 2013
The relative antibody levels against N1N1pdm09 and H3N2 virus NS1 proteins were determined as the last serum dilution showing a positive signal in Western blot analysis. Blue columns show antibody titers against H1N1pdm09 subtype, and yellow columns show
Päivi Olsen (5655913), Turkka Kirjavainen (175086), Markku Partinen (175013), Ritva Syrjänen (443486), Arja Vuorela (443487), Christer Hublin (175027), Outi Saarenpää-Heikkilä (175017), Hanna Nohynek (328056), Krister Melén (443483), Janne Tynell (443484), Ilkka Julkunen (175083), Maarit Sillanpää (443485), Terhi Kilpi (328062), Sari-Leena Himanen (328060), Jorma Ilonen (198952), Outi Vaarala (328058)   +15 more
core   +1 more source

Vaccination against seasonal influenza A/H3N2 virus reduces the induction of heterosubtypic immunity against influenza A/H5N1 virus infection in ferrets

, 2011
Infection with seasonal influenza viruses induces a certain extent of protective immunity against potentially pandemic viruses of novel subtypes, also known as heterosubtypic immunity.
Amerongen, G. (Geert) van, R. A. M. Fouchier, Bodewes, R. (Rogier), Osterhaus, A.D.M.E. (Albert), Fouchier, R.A.M. (Ron), J. H. C. M. Kreijtz, G. F. Rimmelzwaan, Kuiken, T. (Thijs), R. J. Verburgh, G. van Amerongen, Geelhoed-Mieras, M.M. (Martina), Trierum, S.E. (Stella), M. M. Geelhoed-Mieras, Kreijtz, J.H.C.M. (Joost), T. Kuiken, S. E. van Trierum, Verburgh, R.J. (Joyce), A. D. M. E. Osterhaus, Rimmelzwaan, G.F. (Guus), R. Bodewes, Mieras, Tiny, Verburgh, Joyce, Amerongen, Geert, Fouchier, Ron; id_orcid, Kuiken, Thijs, Bodewes, Rogier, Trierum, Stella, Kreijtz, Joost, Rimmelzwaan, Guus, Osterhaus, Ab   +29 more
core   +2 more sources

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Characteristics of Seasonal Influenza Virus Activity in a Subtropical City in China, 2013–2019

, 2020
Background: To optimize seasonal influenza vaccination programs in regions with potentially complicated seasonal patterns, the epidemiological characteristics of seasonal influenza activity in a subtropical city of China were explored.
Jianhua Liu, Zhibing Peng, Zhongjie Li, Aiqin Zhu, Luzhao Feng, Jianxing Yu, Chuchu Ye, Ying Qin, Liping Wang, Yaming Zheng   +9 more
core   +1 more source

Subtype cross-reactive, infection-enhancing antibody responses to influenza A viruses [PDF]

, 2009
Antibody-dependent enhancement of the uptake of influenza A virus by Fc receptor-bearing cells was analyzed by using virus strains of the three human influenza A virus subtypes, A/PR/8/34 (H1N1), A/Japan/305/57 (H2N2), and A/Port Chalmers/1/73 (H3N2 ...
Webster, Robert G., Tamura, Manabu, Ennis, Francis A.   +2 more
core  

Prior immunity to seasonal influenza A(H3N2) virus confers varying levels of cross-protection against challenge with clade 2.3.4.4b A(H5N1), A(H7N9), or A(H9N2) virus in a ferret model

Microbiology Spectrum
Evaluating how prior immunity to seasonal influenza viruses influences subsequent zoonotic influenza A virus (IAV) infection in animal models is critical for pandemic preparedness.
Xiangjie Sun, Jessica A. Belser, Zhu-Nan Li, Feng Liu, Nicole Brock, Joanna A. Pulit-Penaloza, Troy J. Kieran, Claudia Pappas, Hui Zeng, Jessie C. Chang, Paul J. Carney, Brandon L. Bradley-Ferrell, James Stevens, Min Z. Levine, Terrence M. Tumpey, Taronna R. Maines   +15 more
doaj   +1 more source

Swine Influenza (H3N2) Infection in a Child and Possible Community Transmission, Canada

Emerging Infectious Diseases, 2007
An influenza A virus (H3N2) of probable swine origin, designated A/Canada/1158/2006, was isolated from a 7-month-old hospitalized child who lived on a communal farm in Canada. The child recovered uneventfully.
Joan L. Robinson, Bonita E. Lee, Jagdish Patel, Nathalie Bastien, Karen Grimsrud, Robert F. Seal, Robin King, Frank Marshall, Yan Li   +8 more
doaj   +1 more source

Some Exposure for Influenza Hemagglutinin Interface Antibodies

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Influenza viruses are a constant threat to human health. Current vaccines often confer low to moderate protection against infection with seasonal viruses and little‐to‐no protection against pandemic viruses. Improved vaccines are needed. These vaccines will need to reliably elicit antibodies to conserved sites that are broadly protective.
Kevin R. McCarthy
wiley   +1 more source