Results 131 to 140 of about 318,757 (356)

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

open access: yesAdvanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu   +17 more
wiley   +1 more source

Subclasses of certain analytic functions

open access: yesHokkaido Mathematical Journal, 2003
Let \(A\) denote the class of functions \(f(z)=z+ \sum^\infty+ {n=2}a_nz^n\) which are analytic in the open unit disc \(E\) of the complex plane. Let \(H(\lambda,\mu)\) \((\text{Re} \lambda\geq 0\), \(\mu\geq 0)\) denote the subclass of \(A\) consisting of functions \(f(z)\) with \(f(z)\neq 0\) for \(z\neq 0\) and \[ \left|{z^2f'(z)\over\bigl(f(z)\bigr)
YANG, Dinggong, OWA, Shigeyoshi
openaire   +3 more sources

Arabidopsis TRB Proteins Form Two Closely Related Complexes to Mediate H3K4me3 Demethylation and Transcriptional Repression

open access: yesAdvanced Science, EarlyView.
This study reveals that Arabidopsis telomere repeat binding proteins (TRBs) form two closely related complexes. These complexes mediate H3K4me3 demethylation and transcriptional repression through a positive feedback loop and cooperate with PEAT and PRC2 complexes to regulate multiple histone modifications and gene expression across the genome ...
Qi Wang   +7 more
wiley   +1 more source

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

open access: yesAdvanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie   +8 more
wiley   +1 more source

On a subclass of ∞-regular languages

open access: yesTheoretical Computer Science, 1988
AbstractG-machines are considered as generators of sets of finite and infinite sequences, called G-languages. This paper focuses on the characterization of G-languages in terms of ∞-regular languages. It is shown that the class of G-languages is a proper subclass of the class of ∞-regular languages. It is also pointed out that the deterministic version
openaire   +2 more sources

The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset

open access: yesAdvanced Science, EarlyView.
The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng   +22 more
wiley   +1 more source

Super‐Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation

open access: yesAdvanced Science, EarlyView.
A novel chromatin‐labeling probe is developed to investigate chromatin mobility during differentiation. The silicon rhodamine–conjugated dCTP is efficiently delivered into iPSCs and NSCs using a synthetic transporter. Super‐resolution microscopy and single‐particle tracking show decreased chromatin mobility during differentiation.
Maruthi K. Pabba   +11 more
wiley   +1 more source

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