The tCAP(N3) reagent, featuring a stable and self‐activating precursor, enables site‐specific conjugation of native IgGs. This Fc‐affinity peptide approach selectively transfers an Ac‐Lys(N3)‐Gly‐Gly payload to Lys248, producing divalently azidated antibody while preserving its biological function.
Hiroko Kawakami +12 more
wiley +1 more source
Salivary proteomics of patients with type 2 diabetes identify potential biomarkers for diabetes and highlight significant role of immune response. [PDF]
Zhang Y +7 more
europepmc +1 more source
Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis
Mechanochemistry offers a sustainable, solvent‐free alternative to traditional synthesis, often enhanced by additives in a process known as additive‐assisted grinding. This review discusses how various additives, including liquids, ionic solids, and advanced materials like ionic liquids and piezoelectric compounds, improve reaction efficiency ...
Johanna Breinsperger +3 more
wiley +1 more source
A Multigene Perspective on the Phylogeny and Evolutionary Relationships of Class Spirotrichea (Ciliophora). [PDF]
Li B +5 more
europepmc +1 more source
Partially-supervised protein subclass discovery with simultaneous annotation of functional residues [PDF]
Benjamin Georgi +2 more
openalex +1 more source
Rank‐based estimation of propensity score weights via subclassification
Abstract Propensity score (PS) weighting estimators are widely used for causal effect estimation and enjoy desirable theoretical properties, such as consistency and potential efficiency under correct model specification. However, their performance can degrade in practice due to sensitivity to PS model misspecification.
Linbo Wang +3 more
wiley +1 more source
The potential role of IgG subclass in NF155-associated nodopathy for targeting therapy: a pediatric case report highlighting the efficacy of pulsed oral corticosteroids. [PDF]
Turčanová Koprušáková M +4 more
europepmc +1 more source
New Subclass of Meromorphic Functions Defined via Mittag–Leffler Function on Hilbert Space
Mohammad El-Ityan +5 more
openalex +1 more source
A Markov approach to credit rating migration conditional on economic states
Abstract We develop a model for credit rating migration that accounts for the impact of economic state fluctuations on default probabilities. The joint process for the economic state and the rating is modelled as a time‐homogeneous Markov chain. While the rating process itself possesses the Markov property only under restrictive conditions, methods ...
Michael Kalkbrener, Natalie Packham
wiley +1 more source

