Results 281 to 290 of about 318,757 (356)

Immunoglobulin class and IgG subclass distribution of anticardiolipin antibodies in patients with systemic lupus erythematosus and associated disorders

, 1992
S. Loizou, C COFINER, Anthony P. Weetman, Mark Walport   +3 more
openalex   +2 more sources

Phenotype characterization of heart failure with preserved ejection fraction in medical device and surgical trials

ESC Heart Failure, EarlyView.
This systematic review identified 24 clinical trials of medical device and surgical interventions for HFpEF, with 16 demonstrating at least safety and feasibility, but little evidence of long‐term benefit. Phenotype‐based responses suggest that certain interventions may benefit specific HFpEF subgroups, yet most trials suffered from heterogeneous ...
Kurdo Araz, Francesco Fioretti, Sara Ladak, Mohammed Obaidan, Javed Butler, Aamir Hameed   +5 more
wiley   +1 more source

Cost-Effective Method for Full-Length Sequencing of Monoclonal Antibodies from Hybridoma Cells. [PDF]

Antibodies (Basel)
Döring S, Tscheuschner G, Flemig S, Weller MG, Konthur Z.   +4 more
europepmc   +1 more source

The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches

ESC Heart Failure, EarlyView.
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori, Sergio Davinelli, Armando Ferrera, Alessandro Medoro, Carlo Barsali, Allegra Battistoni, Maurizio Volterrani, Massimo Volpe, Luciano Saso, Speranza Rubattu   +9 more
wiley   +1 more source

Genetic Diversity Evaluation of 70 Chewing Cane Germplasm Resources Based on Phenotypic Traits. [PDF]

Plants (Basel)
Xie J, Liu Z, Chang H, Zhang C, Liang Q, Wang Z, Cheng Y, Wang Q, Wu J.   +8 more
europepmc   +1 more source

Global patterns of polypharmacy after acute heart failure hospitalization: Prevalence and outcomes from the REPORT‐HF registry

European Journal of Heart Failure, EarlyView.
Global patterns of polypharmacy after acute heart failure hospitalization. GDMT, guideline‐directed medical therapy; HF, heart failure. Aims Polypharmacy, defined as the concurrent use of ≥5 medications, is prevalent among older adults with heart failure (HF).
Wan Ting Tay, Tiew‐Hwa Katherine Teng, Wouter Ouwerkerk, John G.F. Cleland, Sean P. Collins, Christiane E. Angermann, Kenneth Dickstein, Ulf Dahlstrom, Anja Schweizer, Achim Obergfell, Kai‐Hang Yiu, Mathieu Ghadanfar, Mahmoud Hassanein, Qing‐Wen Ren, Wen‐Li Gu, Georg Ertl, Sergio V. Perrone, Gerasimos Filippatos, Carolyn S.P. Lam, Jasper Tromp   +19 more
wiley   +1 more source

Clinical, Electrophysiologic, and Pathologic Features of Anti-Contactin-Associated Protein 1 Autoimmune Nodopathy. [PDF]

Neurology
Tashiro T, Ogata H, Fukami Y, Maimaitijiang G, Hayashida H, Deguchi K, Hamada Y, Ito Y, Kanai M, Katsumoto A, Kishi R, Koga M, Kurokawa T, Machida A, Mihara M, Miyaue N, Mori Y, Naba I, Nakae Y, Nakamura A, Nishimura H, Okamoto T, Saji E, Satake R, Sekiguchi K, Shibuya M, Shimoda M, Shimohata T, Takeda Y, Taneda K, Tezuka T, Togo M, Uehara T, Yamaguchi K, Yoshikura N, Yamasaki R, Kira JI, Koike H, Katsuno M, Isobe N.   +39 more
europepmc   +1 more source

1,3‐Diazetidin‐2‐Ones: Synthetic Approaches and Therapeutic Promise within the Aza‐β‐Lactam Family

European Journal of Organic Chemistry, EarlyView.
This review explores the synthesis, reactivity, and therapeutic potential of 1,3‐diazetidin‐2‐ones—an underexplored class of aza‐β‐lactams. Emphasis is placed on synthetic challenges, emerging methodologies, and their promise as β‐lactamase‐resistant scaffolds in medicinal chemistry. 1,3‐diazetidin‐2‐ones, overlooked members of the aza‐β‐lactam family,
Jozef Kristek, Jiří Pospíšil
wiley   +1 more source

Anti-SARS-CoV-2 Spike IgA2 Induces Inflammation by Human Macrophages. [PDF]

Eur J Immunol
Mes L, Veth J, Van Coillie J, Keijser JBD, Mantel E, van der Mast R, Rispens T, Vidarsson G, van Egmond M, den Dunnen J, Chen HJ.   +10 more
europepmc   +1 more source

AI‐based localization of the epileptogenic zone using intracranial EEG

Epilepsia Open, EarlyView.
Abstract Artificial intelligence (AI) is rapidly transforming our lives. Machine learning (ML) enables computers to learn from data and make decisions without explicit instructions. Deep learning (DL), a subset of ML, uses multiple layers of neural networks to recognize complex patterns in large datasets through end‐to‐end learning.
Atsuro Daida, Yipeng Zhang, Sotaro Kanai, Richard Staba, Vwani Roychowdhury, Hiroki Nariai   +5 more
wiley   +1 more source