Results 1 to 10 of about 232,592 (214)

Unbiased plasma proteomics discovery of biomarkers for improved detection of subclinical atherosclerosis

EBioMedicine, 2022
Summary: Background: Imaging of subclinical atherosclerosis improves cardiovascular risk prediction on top of traditional risk factors. However, cardiovascular imaging is not universally available.
Estefanía Núñez, Valentín Fuster, María Gómez-Serrano, José Manuel Valdivielso, Juan Miguel Fernández-Alvira, Diego Martínez-López, José Manuel Rodríguez, Elena Bonzon-Kulichenko, Enrique Calvo, Alvaro Alfayate, Marcelino Bermudez-Lopez, Joan Carles Escola-Gil, Leticia Fernández-Friera, Isabel Cerro-Pardo, José María Mendiguren, Fátima Sánchez-Cabo, Javier Sanz, José María Ordovás, Luis Miguel Blanco-Colio, José Manuel García-Ruiz, Borja Ibáñez, Enrique Lara-Pezzi, Antonio Fernández-Ortiz, José Luis Martín-Ventura, Jesús Vázquez   +24 more
doaj   +3 more sources

Variants of PCSK9 Gene Are Associated with Subclinical Atherosclerosis and Cardiometabolic Parameters in Mexicans. The GEA Project

Diagnostics, 2021
Background: Coronary artery disease (CAD) is a chronic, inflammatory, and complex disease associated with vascular risk factors. Nowadays, the coronary artery calcium (CAC) is a specific marker of the presence and extent of atherosclerosis. Additionally,
Erasmo Zamarrón-Licona, José Manuel Rodríguez-Pérez, Rosalinda Posadas-Sánchez, Gilberto Vargas-Alarcón, Manuel Alfonso Baños-González, Verónica Marusa Borgonio-Cuadra, Nonanzit Pérez-Hernández   +6 more
doaj   +1 more source

Association of subclinical atherosclerosis and cognitive decline: a community-based cross-sectional study

BMJ Open, 2022
Background and aims Growing burden of dementia was considered as a global public health priority as its epidemic scale rises with the world’s population increases in age. In the absence of effective treatment, early identification of decline in cognitive
Yao Lu, Rong Hua, Wuxiang Xie, Chenglong Li, Hongyu Wang, Yidan Zhu, Yanjun Ma, Baoliang Zhong   +7 more
doaj   +1 more source

High serum Bhlhe40 levels are associated with subclinical atherosclerosis in patients with type 2 diabetes mellitus: A cross-sectional study

Diabetes & Vascular Disease Research, 2023
Background Our previous studies have shown that the basic helix-loop-helix family member e40 (Bhlhe40) plays a critical role in regulating calcification and senescence of vascular smooth muscle cells induced by high glucose.
Hui Xu, Qun-Yan Xiang, Shuang Li, You-Shuo Liu   +3 more
doaj   +1 more source

Sex Modifies the Association of Fibroblast Growth Factor 21 With Subclinical Carotid Atherosclerosis

Frontiers in Cardiovascular Medicine, 2021
Background and Aims: Fibroblast growth factor 21 (FGF21), an emerging metabolic hepatokine, is associated with atherosclerosis. An interaction with sex has been described in various populations.
Yingjie Chee, Grace Lx Toh, Chien Joo Lim, Liuh Ling Goh, Rinkoo Dalan, Rinkoo Dalan   +5 more
doaj   +1 more source

Associations Between the Macular Microvasculatures and Subclinical Atherosclerosis in Patients With Type 2 Diabetes: An Optical Coherence Tomography Angiography Study

Frontiers in Medicine, 2022
ObjectiveTo investigate the associations between the macular microvasculature assessed by optical coherence tomography angiography (OCTA) and subclinical atherosclerosis in patients with type 2 diabetes.MethodsWe included patients with type 2 diabetes ...
Jooyoung Yoon, Hyo Joo Kang, Joo Yong Lee, Joo Yong Lee, June-Gone Kim, June-Gone Kim, Young Hee Yoon, Young Hee Yoon, Chang Hee Jung, Chang Hee Jung, Yoon Jeon Kim, Yoon Jeon Kim   +11 more
doaj   +1 more source

Klotho as a biomarker of subclinical atherosclerosis in patients with moderate to severe chronic kidney disease

Scientific Reports, 2021
Chronic kidney disease (CKD) has been associated with a higher risk of cardiovascular disease (CVD). CKD patients present a decrease in the levels of the protein Klotho that accompanies the decrease in kidney function.
Javier Donate-Correa, Carla M. Ferri, Ernesto Martín-Núñez, Nayra Pérez-Delgado, Ainhoa González-Luis, Carmen Mora-Fernández, Juan F. Navarro-González   +6 more
doaj   +1 more source

Subclinical atherosclerosis, cardiovascular health, and disease risk: is there a case for the Cardiovascular Health Index in the primary prevention population?

BMC Public Health, 2018
Background Current primary prevention guidelines for cardiovascular disease (CVD) prioritize risk identification, risk stratification using clinical and risk scores, and risk reduction with lifestyle interventions and pharmacotherapy.
Sarah S. Singh, Courtney S. Pilkerton, Carl D. Shrader, Stephanie J. Frisbee   +3 more
doaj   +1 more source

Metabolic health phenotype better predicts subclinical atherosclerosis than body mass index-based obesity phenotype in the non-alcoholic fatty liver disease population

Frontiers in Nutrition, 2023
BackgroundNon-alcoholic fatty liver disease (NAFLD), especially lean NAFLD is associated with an increased risk of atherosclerotic cardiovascular disease (CVD).
Yaqin Wang, Ting Yuan, Shuwen Deng, Xiaoling Zhu, Yuling Deng, Xuelian Liu, Lei Liu, Changfa Wang   +7 more
doaj   +1 more source

HIV Infection Itself May Not Be Associated With Subclinical Coronary Artery Disease Among African Americans Without Cardiovascular Symptoms

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe key objectives of this study were to examine whether HIV infection itself is associated with subclinical coronary atherosclerosis and the potential contributions of cocaine use and antiretroviral therapies (ARTs) to subclinical coronary ...
Hong Lai, Richard Moore, David D. Celentano, Gary Gerstenblith, Glenn Treisman, Jeanne C. Keruly, Thomas Kickler, Ji Li, Shaoguang Chen, Shenghan Lai, Elliot K. Fishman   +10 more
doaj   +1 more source