Gradients of striatal function in antipsychotic-free first-episode psychosis and schizotypy
Both psychotic illness and subclinical psychosis-like experiences (PLEs) have been associated with cortico-striatal dysfunction. This work has largely relied on a discrete parcellation of the striatum into distinct functional areas, but recent evidence ...
Marianne Oldehinkel +18 more
doaj +1 more source
BackgroundThe clinical high-risk for psychosis (CHR) paradigm is one of the best studied preventive paradigms in psychiatry. However, most studies have been conducted in high-income countries. It is unclear if knowledge from such countries applies to low
Alexandre Andrade Loch +13 more
doaj +1 more source
Background: Hearing deterioration in hypothyroid subject was documented by Kemp. Cristiane et al. reported delayed waves latency in subclinical hypothyroid subjects.
Indira Jha +4 more
doaj +1 more source
Positive and negative subclinical symptoms and MCCB performance in non-psychiatric controls
Considerable data support the phenomenological and temporal continuity between subclinical psychosis and psychotic disorders. In recent years, neurocognitive deficits have increasingly been recognized as a core feature of psychotic illness but there are ...
Cole Korponay +3 more
doaj +1 more source
Psychotic-Like Experiences: A Challenge in Definition and Assessment
Assuming a continuum between psychotic experiences and psychotic symptoms aligned between healthy individuals and patients with non-psychotic and psychotic disorders, recent research has focused on subclinical psychotic experiences.
Barbara Hinterbuchinger +1 more
doaj +1 more source
Psychotic symptoms in young adults exposed to childhood trauma - A 20 year follow-up study [PDF]
Childhood adversity has been shown to increase the risk of psychotic symptoms in adult life. However, there are no previous studies looking at the association between experiencing a natural disaster during childhood and the development of psychotic ...
Alexander McFarlane +46 more
core +2 more sources
Can obsessions drive you mad? Longitudinal evidence that obsessive-compulsive symptoms worsen the outcome of early psychotic experiences [PDF]
Although there is substantial comorbidity between psychotic disorder and obsessive-compulsive disorder (OCD), little is known about how these clinical phenotypes, and their subclinical extended phenotypes, covary and impact on each other over time.
Association +66 more
core +2 more sources
SA9. Associations of Subclinical Psychosis Spectrum Characteristics, Childhood Depressive Symptoms, and Schizophrenia Polygenic Risk Score: Analyses From the Philadelphia Neurodevelopmental Cohort [PDF]
Owrutsky Z, Ahmed A.
europepmc +2 more sources
Negative cognition, affect, metacognition and dimensions of paranoia in people at ultra-high risk of psychosis: a multi-level modelling analysis [PDF]
Background: Paranoia is one of the commonest symptoms of psychosis but has rarely been studied in a population at risk of developing psychosis. Based on existing theoretical models, including the proposed distinction between ‘poor me’ and ‘bad me ...
Bentall, R.P. +10 more
core +2 more sources
Introduction Adolescents presenting with a first psychotic episode often have a long history of pediatric treatment. However, there is insufficient evidence of children’s subclinical characteristics in non-psychiatric settings. To address this issue, we
Y. Hamasaki +7 more
doaj +1 more source

