Results 171 to 180 of about 14,956 (263)

Efficient Channel Attention-Gated Graph Transformer for Aero-Engine Remaining Useful Life Prediction. [PDF]

open access: yesACS Omega
Chen C   +7 more
europepmc   +1 more source

Untangling nutrient co‐regulation of ombrotrophic peatland development

open access: yesBoreas, EarlyView.
Multi‐method (FTIR, FT‐NIR and TGA) approaches characterizing the organic peat constituents at Holcroft Moss reveal a record of switches that reflect broadly hydroclimate variability governing the decomposition patterns. There are periods, however, where hydroclimate does not fully explain the variability observed and instead changes appear linked to ...
Richard C. Chiverrell   +6 more
wiley   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

open access: yesBrain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira   +19 more
wiley   +1 more source

Transcriptomic analysis reveals lipid metabolism and macrophage involvement associated with nintedanib treatment in a rat bleomycin model

open access: yesBritish Journal of Pharmacology, EarlyView.
In this study, nintedanib reduced lung fibrosis in a rat double‐hit bleomycin‐induced model. Transcriptomic analysis revealed two key gene signatures related to the effect of the molecule: one involving mesenchymal cells affecting known fibrotic pathways and another linking mainly macrophages to lipid metabolism.
Martina Bonatti   +14 more
wiley   +1 more source

Mesoscopic vascular alterations in Alzheimer's disease. [PDF]

open access: yesAlzheimers Dement
Hyman M   +16 more
europepmc   +1 more source

Single‐Cell Analysis Identified a Recurrent Malignant‐Associated Transcriptional State in Colorectal Cancer

open access: yesCancer Science, EarlyView.
Colorectal cancer (CRC) shows high molecular heterogeneity, yet single‐cell data from Japanese patients are limited. We performed scRNA‐seq on tumors and adjacent normal tissues from four Japanese CRC patients and identified a shared malignant cell cluster with high KCNQ1OT1 expression and reduced RASSF6 levels.
Sadahiro Iwabuchi   +15 more
wiley   +1 more source

NOL7 Inhibits Ovarian Cancer Progression and Suppresses Angiogenesis by Stabilizing GADD45A to Deactivate STAT3

open access: yesCancer Science, EarlyView.
NOL7 acts as a tumor‐suppressor in ovarian cancer. Overexpression of NOL7 up‐regulated GADD45A expression by stabilizing GADD45A mRNA in ovarian cancer cells. ABSTRACT Ovarian cancer is one of the most prevalent gynecologic malignancies worldwide. Dysregulated cell proliferation and angiogenesis are well‐recognized to be involved in the pathogenesis of
Xinyu Xu   +3 more
wiley   +1 more source

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