Results 181 to 190 of about 14,956 (263)

Fetal Fraction Signatures: A Quality Control Tool to Detect Potentially Confounding Situations in NonInvasive Prenatal Diagnosis of Monogenic Conditions

open access: yesClinical Genetics, EarlyView.
Noninvasive prenatal diagnosis for monogenic diseases (NIPD‐M) to detect inherited mutations is performed in parallel with fetal fraction signatures, to detect various anomalies that may compromise diagnosis. An extra regression analysis may be necessary to resolve mosaic situations. ABSTRACT Noninvasive prenatal diagnosis relies on the analysis of the
Jean‐Louis Blouin   +2 more
wiley   +1 more source

Mass drug administration of praziquantel lowers the susceptibility of school-aged children to <i>Schistosoma mansoni</i> in endemic areas. [PDF]

open access: yesFront Immunol
Nono JK   +8 more
europepmc   +1 more source

Hierarchical Differentiable Fluid Simulation

open access: yesComputer Graphics Forum, EarlyView.
We introduce a two‐step algorithm that significantly reduces memory usage for solving control problems using differentiable fluid simulation techniques: our method first optimizes for bulk forces at reduced resolution, then refines local details over sub‐domains while maintaining differentiability. In trading runtime for memory, it enables optimization
Xiangyu Kong   +4 more
wiley   +1 more source

Addressing environmental misperceptions for nature recovery

open access: yesConservation Biology, EarlyView.
Abstract A poorly understood and systemic challenge to global conservation agreements is shifting baseline syndrome (SBS), wherein people misperceive the extent to which nature has changed. This can diminish societal expectations for nature recovery. We broadened the conceptual framing of SBS beyond the more common elements of nature loss to include ...
Shuo Gao   +3 more
wiley   +1 more source

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis

open access: yesCell Proliferation, EarlyView.
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu   +16 more
wiley   +1 more source

Craniofacial integration and modularity in untreated cleft lip and palate. [PDF]

open access: yesClin Oral Investig
Sumardi S   +4 more
europepmc   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

open access: yesCell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma   +20 more
wiley   +1 more source

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