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NHE1 gene associated with avian leukosis virus subgroup J infection in chicken

Molecular Biology Reports, 2014
As a kind of binding protein, the type 1 Na(+)/H(+) exchanger (NHE1) is a receptor for the highly pathogenic Avian leukosis viruses-J subgroup (ALV-J) in chicken. In order to investigate the potential effect of chicken NHE1 gene on leukosis, we compared its expression between ALV-J-affected and -unaffected chicken, screened variations across the whole ...
Biao, Chen   +6 more
openaire   +2 more sources

Differential expression of microRNAs in avian leukosis virus subgroup J-induced tumors

Veterinary Microbiology, 2013
Avian leukosis virus subgroup J (ALV-J) has become pandemic and induced serious clinical outbreaks in chickens in China. In particular, ALV-J induced various clinical tumors in infected chickens, which caused enormous economic losses to poultry.
Qi, Wang   +7 more
openaire   +2 more sources

Recombinant invasive Lactobacillus plantarum expressing the J subgroup avian leukosis virus Gp85 protein induces protection against avian leukosis in chickens

Applied Microbiology and Biotechnology, 2021
Avian leukosis, caused by avian leukosis virus (ALV), is an infectious tumor disease and severely hinders the development of the poultry industry. The use of Lactobacillus plantarum (L. plantarum) could effectively alleviate viremia in the early period of J subgroup ALV (ALV-J) infection. In this study, an invasive L.
Jing Liu   +9 more
openaire   +2 more sources

[Cross-species Transmission of Avian Leukosis Virus Subgroup J].

Bing du xue bao = Chinese journal of virology, 2016
Avian leukosis virus subgroup J (ALV-J) is an avian retrovirus that can induce myelocytomas. A high-frequency mutation in gene envelope endows ALV-J with the potential for cross-species transmission. We wished to ascertain if the ALV-J can spread across species under selection pressure in susceptible and resistant hosts.
Yanwei, Shen   +5 more
openaire   +1 more source

Avian leukosis virus subgroup J: a rapidly evolving group of oncogenic retroviruses

Research in Veterinary Science, 1999
A strain of avian leukosis virus (ALV) belonging to a new envelope subgroup J was isolated in the UK in 1988 from meat-type chickens. The disease caused by the members of this subgroup has since spread very rapidly worldwide and has become one of the major problems facing the broiler meat industry. Molecular characterisation of HPRS -103, the prototype
openaire   +2 more sources

Efficacy of an autophagy-targeted DNA vaccine against avian leukosis virus subgroup J

Vaccine, 2017
Infection with the avian leukosis virus subgroup J (ALV-J) can lead to neoplastic disease in chickens, inflicting significant economic losses to the poultry industry. Recent reports have identified inhibitory effects of ALV-J on autophagy, a process involving in innate and adaptive immunity.
Dai, Zhenkai   +9 more
openaire   +3 more sources

Geese not susceptible to virulent subgroup J avian leukosis virus isolated from chickens

Avian Pathology, 2019
To determine whether geese are susceptible to infection by avian leukosis virus (ALV), 702 serum samples from domestic and foreign goose breeds were screened for p27 antigen as well as being inoculated into DF-1 cell cultures to isolate ALV. Although 5.7% of samples were positive for p27 antigen, reactivity appeared to be non-specific because no ALV ...
Xiaohui, Mu   +5 more
openaire   +2 more sources

Genetic mutations of avian leukosis virus subgroup J strains extended their host range

Journal of General Virology, 2014
The genetic diversity of avian leukosis virus subgroup J (ALV-J) is determined not only by the env gene, but also by its 3′ UTR and 3′ LTR. They all play important roles in extending the host range and tumour development. In the present study, one ALV-J strain (ZB110604-6) from Black-Bone Silky Fowl (BSF) and three ALV-J strains (ZB110604-3/4/5) from ...
Yanwei, Shen   +7 more
openaire   +2 more sources

Detection of subgroup J avian leukosis virus infection in Australian meat‐type chickens

Australian Veterinary Journal, 2004
Objective To determine the extent of avian leukosis virus subgroup J (ALV‐J) infection in Australian broiler breeder flocks, using virus isolation and molecular biological detection. Any resultant ALV‐J viral isolates to be characterised by neutralisation cross testing in order to determine antigenic relationships to overseas isolates of ALV‐J.
T J, Bagust, S P, Fenton, M R, Reddy
openaire   +2 more sources

A novel multi-variant epitope ensemble vaccine against avian leukosis virus subgroup J

Vaccine, 2017
The hypervariable antigenicity and immunosuppressive features of avian leukosis virus subgroup J (ALV-J) has led to great challenges to develop effective vaccines. Epitope vaccine will be a perspective trend. Previously, we identified a variant antigenic neutralizing epitope in hypervariable region 1 (hr1) of ALV-J, N-LRDFIA/E/TKWKS/GDDL/HLIRPYVNQS-C ...
Xiaoyu, Wang   +6 more
openaire   +2 more sources

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