Results 61 to 70 of about 1,739 (160)

Vertical transmission of avian leukosis virus subgroup J (ALV-J) from hens infected through artificial insemination with ALV-J infected semen

BMC Veterinary Research, 2017
Background Avian leukosis virus (ALV) is one of the main causes of tumour development within the poultry industry in China. The subgroup J avian leukosis viruses (ALV-J), which induce erythroblastosis and myelocytomatosis, have the greatest pathogenicity
Yang Li, Shuai Cui, Weihua Li, Yixin Wang, Zhizhong Cui, Peng Zhao, Shuang Chang   +6 more
doaj   +1 more source

New developments in biotechnology applied to animals: An assessment of the adequacy and sufficiency of current EFSA guidance for animal risk assessment

EFSA Journal, Volume 23, Issue 8, August 2025.
Abstract EFSA was requested by the European Commission to provide a scientific opinion on new developments in biotechnology, including new genomic techniques, as applied to animals for food, feed and other agricultural uses. A horizon‐scanning exercise identified a variety of animals obtained with new genomic techniques, with the potential to reach the
EFSA Panel on Genetically Modified Organisms (GMO), Josep Casacuberta, Francisco Barro, Albert Braeuning, Ruud de Maagd, Michelle M. Epstein, Thomas Frenzel, Jean‐Luc Gallois, Frits Koning, Antoine Messéan, F. Javier Moreno, Fabien Nogué, Alan H. Schulman, Christoph Tebbe, Eve Veromann, Leslie Firbank, Debora Glandorf, Mette S. Herskin, Simon Geoffrey Lillico, Robin Ornsrud, Anna Troedsson‐Wargelius, Michele Ardizzone, Paolo Lenzi, Ana M. Camargo, Nikoletta Papadopoulou, Reinhilde Schoonjans, Marika Vitali, Giovanni Savoini   +27 more
wiley   +1 more source

Extracellular RNA in viral–host interactions: Thinking outside the cell

WIREs RNA, Volume 10, Issue 4, July/August 2019., 2019
In normal physiology, host microRNAs (miRNAs) exported in extracellular vesicles (EVs) are involved in cell‐to‐cell communication and in maintaining homeostasis. Upon viral infection, the miRNA cargo of the EVs can be altered and enriched for specific (viral or host) miRNAs which influence immune responses in the recipient cell and alter the ...
Sarah Ressel, Adelina Rosca, Katrina Gordon, Amy H. Buck   +3 more
wiley   +1 more source

ACSL1 Inhibits ALV-J Replication by IFN-Ⅰ Signaling and PI3K/Akt Pathway

Frontiers in Immunology, 2021
J subgroup avian leukosis virus (ALV-J) infection causes serious immunosuppression problems, leading to hematopoietic malignancy tumors in chicken.
Qihong Zhang, Qihong Zhang, Qihong Zhang, Tingting Xie, Tingting Xie, Tingting Xie, Guodong Mo, Guodong Mo, Guodong Mo, Zihao Zhang, Zihao Zhang, Zihao Zhang, Ling Lin, Ling Lin, Ling Lin, Xiquan Zhang, Xiquan Zhang, Xiquan Zhang   +17 more
doaj   +1 more source

Rodent models of tumours of the central nervous system

Molecular Oncology, Volume 18, Issue 12, Page 2842-2870, December 2024.
We describe the evolution of experimental systems, illustrated here in a timeline to show changing popularity over time. Starting with chemical and viral carcinogenesis, systems then developed into increasingly sophisticated genetically modified animal models.
Sebastian Brandner
wiley   +1 more source

Molecular Detection and Genetic Characterization of Avian Leukosis Virus From Field Outbreaks in Bangladesh

Veterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Histopathological examination of the liver from an avian leukosis virus (ALV)‐infected chicken reveals tissue alterations. Molecular detection confirms the presence of ALV in the liver samples. Evolutionary origin analysis traces the identified ALV strain. Mutational analysis and structural examination of the ALV envelope (Env) protein provide insights
Md. Golzar Hossain, Riman Pathan, SM Nazmul Hasan, Anandha Mozumder, Moslema Jahan Mou, Marjana Akter, Chandan Sikder, Riyan Al Islam Reshad, Roni Mia, Sukumar Saha, Tofazzal Islam, Sharmin Akter   +11 more
wiley   +1 more source

The follicle promotes the evolution of variants of avian leukosis virus subgroup J in vertical transmission

Biochemical and Biophysical Research Communications, 2020
Avian leukosis virus (ALV) is one of the main causative agent of tumor development, which brings enormous economic losses to the poultry industry worldwide. ALV can be transmitted horizontally and vertically, and the latter often give rise to more adverse pathogenicity.
Xintao Gao, Qiuchen Li, Lichun Fang, Haozhi Song, Zhizhong Cui, Fanfeng Meng, Zhifang Zhang   +6 more
openaire   +2 more sources

Integrative RNA-seq and ChIP-seq analysis unveils metabolic regulation as a conserved antiviral mechanism of chicken p53

Microbiology Spectrum
The tumor suppressor p53, primarily functioning as a transcription factor, has exhibited antiviral capabilities against various viruses in chickens, including infectious bursal disease virus (IBDV), avian leukosis virus subgroup J (ALV-J), and avian ...
Lu Cui, Xuefeng Li, Zhijie Chen, Zheyi Liu, Yu Zhang, Zongxi Han, Shengwang Liu, Hai Li   +7 more
doaj   +1 more source

CCL4 participates in the reprogramming of glucose metabolism induced by ALV-J infection in chicken macrophages

Frontiers in Microbiology, 2023
Interferon and chemokine-mediated immune responses are two general antiviral programs of the innate immune system in response to viral infections and have recently emerged as important players in systemic metabolism.
Huixian Wu, Huixian Wu, Gul Zaib, Gul Zaib, Gul Zaib, Huan Luo, Wang Guo, Ting Wu, Shutong Zhu, Chenjun Wang, Wenxian Chai, Qi Xu, Qi Xu, Hengmi Cui, Hengmi Cui, Xuming Hu, Xuming Hu, Xuming Hu   +17 more
doaj   +1 more source

Isolation, Molecular Characterisation, and Pathogenicity Analysis of a Novel Recombinant ALV‐J Strain Isolated From Chinese Hetian Chickens

Veterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Reduced mortality: The isolated LY2021J strain of ALV‐J from Hetian chickens showed lower mortality despite causing severe dysplasia. Genetic similarity: LY2021J exhibited high genetic similarity to the Chinese Heilongjiang strain JS14NT01, particularly in the gp85 and pol genes, suggesting a possible common origin.
Tianyu Lei, Liyun Zhuang, Tingting Dai, Qun Niu, Yinli Bao, Weiming Lin, Cuiqin Huang, Xintian Zheng   +7 more
wiley   +1 more source