Results 71 to 80 of about 1,739 (160)

CH25H Promotes Autophagy and Regulates the Malignant Progression of Laryngeal Squamous Cell Carcinoma Through the PI3K‐AKT Pathway

open access: yesCancer Medicine, Volume 13, Issue 20, October 2024.
ABSTRACT Background Laryngeal squamous cell carcinoma (LSCC) is a type of cancer of the respiratory tract that often presents with subtle symptoms at the early stage and is susceptible to recurrence and metastasis. Materials and Methods To find out key regulatory genes involved in LSCC development, we downloaded LSCC‐related sequencing datasets for ...
Zhenfei Xiang   +6 more
wiley   +1 more source

MiR-125b Suppression Inhibits Apoptosis and Negatively Regulates Sema4D in Avian Leukosis Virus-Transformed Cells

open access: yesViruses, 2019
Subgroup J avian leukosis virus (ALV-J), an oncogenic retrovirus, causes hemangiomas and myeloid tumors in chickens. We previously showed that miR-125b is down-regulated in ALV-J-induced tumors.
Chaoqi Ren   +20 more
doaj   +1 more source

DETEKSI DINI PENYAKIT TUMOR SEL DARAH MYELOSIT LEUKOSIS MELALUI PEMERIKSAAN ULAS DARAH

open access: yesJurnal Ilmu Pertanian Indonesia, 2007
Myelocytes blood cell tumor in chicken is a disease caused by retrovirus, avian leukosis virus subgroup J (ALV-J). The virus has the same group as human retrovirus (HIV) which caused AIDS, but the avian type possesses oncogenic properties, that could ...
Dewi Ratih Agungpriyono   +3 more
doaj  

Epitope Mapping of a Monoclonal Antibody against the Gp85 of Avian Leukosis Virus Subgroup J

open access: yesJournal of Veterinary Medical Science, 2012
Avian leukosis virus subgroup J poses a great threat to the poultry industry in China. To reduce the economic losses, a quick method for detection of ALV-J antigen is required for diagnosis and identification of the congenitally transmitting hens. In this study, we report the production and evaluation of one monoclonal antibody (MAb) suitable for ...
SUN, Miao   +5 more
openaire   +3 more sources

Plus-strand RNA viruses hijack Musashi homolog 1 to shield viral RNA from cytoplasmic ribonuclease degradation

open access: yesJournal of Virology
A successful strategy employed by RNA viruses to achieve replication is to evade host cell RNase degradation. However, the mechanisms through which plus-strand RNA viruses effectively shield viral RNA from cellular ribonuclease degradation remain unclear.
Defang Zhou   +13 more
doaj   +1 more source

Difference in pathogenicity of 2 strains of avian leukosis virus subgroup J in broiler chicken

open access: yesPoultry Science, 2019
Avian leukosis virus subgroup J has been found to infect many types of chickens with various genetic backgrounds. The ALV-J strain NX0101, which was isolated from broiler breeders in 2001, mainly induces the formation of myeloid cell tumors. However, strain HN10PY01, which was recently isolated from laying hens, mainly induces the formation of myeloid ...
Guihua Zhang   +8 more
openaire   +2 more sources

Avian leukosis virus p15 interacts with interferon regulatory factor 7 to antagonize the cGAS-STING signaling pathway and promote viral replication

open access: yesJournal of Virology
Cyclic GMP-AMP synthase (cGAS) recognizes viral DNA within the cytoplasm and initiates innate antiviral response through the cGAS-STING pathway. However, viruses have evolved diverse strategies to counteract the cGAS-STING signaling pathway.
Zhouhao Cui   +6 more
doaj   +1 more source

Characterization of avian leukosis virus subgroup J isolated between 1999 and 2013 in China

open access: yesPoultry Science, 2018
Avian leukosis virus subgroup J (ALV-J) has successively infected white feather chickens, layer hens, cultivated yellow chickens, and indigenous chickens; infection rates and tumorigenicity have attracted increasingly extensive attention in China. To clarify the correlation of the epidemiological phenomenon of ALV-J with the evolution of envelope ...
Jianliang, Li   +6 more
openaire   +2 more sources

Aberrant expression of liver microRNA in chickens infected with subgroup J avian leukosis virus

open access: yesVirus Research, 2012
Subgroup J avian leukosis virus (ALV-J) is an oncogenic retrovirus primarily causing myeloid leukosis (ML) in broilers. Although ALV is well under control in a few countries including the USA, poultry industry in many parts of the world continues suffering from serious economic loss due to sporadic or widespread ALV infection, especially ALV-J ...
Hongmei, Li   +10 more
openaire   +2 more sources

Metabolomics analysis of CEF cells infected with avian leukosis virus subgroup J based on UHPLC-QE-MS

open access: yesPoultry Science
: Avian leukosis virus subgroup J (ALV-J) is a retrovirus that can cause immunosuppression and tumors in chicken. However, relative pathogenesis is still not clear.
Menglu Xu   +6 more
doaj   +1 more source

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