Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Subject: Collective Bargaining and Labor Relations [PDF]
Compiled by Susan LaCette.thesescb.pdf: 4909 downloads, before Oct.
LaCette, Susan
core +1 more source
Prevention of Influenza Episodes With Colostrum Compared With Vaccination in Healthy and High-Risk Cardiovascular Subjects [PDF]
M R Cesarone +13 more
openalex +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The subject-in-situ generalization revisited [PDF]
The goal of this paper is to re-examine the status of the condition in (1) proposed in Alexiadou and Anagnostopoulou (2001; henceforth A&A 2001), in view of recent developments in syntactic theory.
Alexiadou, Artemis +1 more
core
Evaluation of the immunogenicity and impact on the latent HIV‐1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy‐treated subjects [PDF]
Gemma Hancock +15 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Using the example of German feminist debates, this paper examines the applicability of intersectional approaches to analyzing the relationship between antifeminism, racism, and sexism, as well as the far-right co-optation of critiques of sexism, using ...
Judith Goetz
doaj +1 more source
Population Pharmacokinetic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using a Michaelis–Menten Approximation of a Target-Mediated Drug Disposition Model—Support for a Biologics License Application Submission: Part I [PDF]
Jean-Marie Martinez +5 more
openalex +1 more source

