Results 111 to 120 of about 5,905,131 (283)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Using the example of German feminist debates, this paper examines the applicability of intersectional approaches to analyzing the relationship between antifeminism, racism, and sexism, as well as the far-right co-optation of critiques of sexism, using ...
Judith Goetz
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
University Archives Subject File Collection
Contents of the subject file as of 2/15/2012. From the file Dueling, University Archives Subject File Collection, Special Collections Research Center, Earl Gregg Swem Library, College of William and ...
College of William and Mary
core
Secondary PGCE PE students’ perceptions of their subject knowledge [PDF]
PE teachers in England are required to teach a wide range of physical activities in order to fulfil the requirements of the National Curriculum for Physical Education (NCPE).
Katene, W, Capel, S
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Subject Access; Preparing for the Future
This volume contains the proceedings of a special conference held in Florence, August 2009. The theoretical and methodological aspects of rethinking semantic access to information and knowledge are explored.
IFLA Subject Analysis and Access Section
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
University Archives Subject Files, Students--Famous [PDF]
Materials from : UA Subject File Collection: Series 1, Cabinet 4, Drawer 4: Speakers Forum - Students in local ...
College of William and Mary
core

