Results 81 to 90 of about 4,807,056 (291)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Does integrated science education improve scientific literacy?

JETEN, 2014
In Flanders, a choice has been made for the integrated school subject ‘Natural Sciences’, in ‘science for all’ secondary school trajectories, and for the three separate subjects biology, physics and chemistry, in trajectories for the future scientist and
Laura Tamassia, Renaat Frans
doaj  

Eco-Conscious Packaging: Exploring Sugarcane Bagasse-Based Tableware Manufacturing in India [PDF]

E3S Web of Conferences
This research study presents a solution to combat plastic pollution by creating biodegradable tableware from bagasse, a byproduct of the sugar industry, as an eco-friendly alternative to conventional plastics.
Khoisnam Nikita, Sandhu Harpinder Singh, Awatade Sudarshan C., Subba Ranjit, Dulal Jaya Prakash   +4 more
doaj   +1 more source

In search of dimensions of subject from the standpoint of Ranganathan [PDF]

, 2013
This paper highlights a new interpretation of dynamic state of subject from the viewpoint of Ranganathan’s theory. Ranganathan introduced following three concepts in order to describe the state of subject, viz.
Sen, B. K., Dutta, Bidyarthi, Sen, B K, Majumder, Krishnapada   +3 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Exploring young people's visual perceptions of nature on urban school grounds: Insights from a visitor‐employed photography walk for environmental education

People and Nature
Urban growth and densification increasingly limit children's and young people's access to natural environments. Since they spend a considerable amount of time within school grounds and their immediate surroundings during their childhood, daily encounters
Johanna Trummer, Lucas Weinberg, Jerylee Wilkes‐Allemann, Karin Oberauer, Lars Keller   +4 more
doaj   +1 more source

Annual Subject Index

, 2006
Annual Subject ...
Index, Subject
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Annual Subject Index

, 2005
Annual Subject ...
Index, Subject
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source