Results 101 to 110 of about 7,822,595 (348)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Dyplomy ormiańskie w zbiorach Działu Rękopisów Zakładu Narodoweg o im. Ossolińskich

Lehahayer, 2015
In the Wrocław collections of the Zakład Narodowy im. Ossolińskich [The National Ossoliński Institution] there are 3270 diplomas among which only seventeen may be classified as documents which are associated with Armenians in any way.
Konrad Rzemieniecki
doaj  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Indonesian state educational universities’ bibliometric dataset

Data in Brief, 2019
This data article presents an important bibliometric dataset of ten Indonesian leading educational universities. These ten Indonesian leading educational universities are Universitas Pendidikan Indonesia (UPI), Universitas Negeri Malang (UM), Universitas
Lantip Diat Prasojo, Reni Fatmasari, Eti Nurhayati, Ahmad Darmadji, Fitri Ayu Kusumaningrum, Yuli Andriansyah   +5 more
doaj  

The Phanariots and Their Subjects in Official Documents (1700–1830) [PDF]

, 2023
Constanța Vintilă
openalex   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Analyse de l’activité tutorale dans un organisme privé de formation à distance selon le modèle d’Engeström : tensions et écarts au prescrit

Distances et Médiations des Savoirs, 2016
This study explores e-tutors’ real work. It refers to the Activity Theory developed by Engeström (1987). It is based upon several types of data: ethnographic data, an instructional document, a questionnaire and individual interviews.
Melissa Dir, Stéphane Simonian
doaj   +1 more source

G20210A Prothrombin Gene Polymorphism and Prothrombin Activity in Subjects With or Without Angiographically Documented Coronary Artery Disease [PDF]

, 2001
Carla Russo, Domenico Girelli, Oliviero Olivieri, Patrizia Guarini, Franco Manzato, Francesca Pizzolo, Barbara Zaia, Alessandro Mazzucco, Roberto Corrocher   +8 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source