Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
États-Unis. Library of Congress. Subject Cataloging Division. Introduction à la huitième édition de Library of Congress Subject Headings; version française établie conjointement à la Bibliothèque de l’Université Laval et à la Bibliothèque nationale du Québec. Québec, Université Laval, Bibliothèque; Montréal, Bibliothèque nationale du Québec, 1979. XI, 208 p. [PDF]
, 1980 Monique Arnoldi
openalex +1 more source
Special Libraries, February 1951 [PDF]
, 1951 Volume 42, Issue 2https://scholarworks.sjsu.edu/sla_sl_1951/1001/thumbnail ...
Special Libraries Association
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Chapter 2 - A Discussion of Methods, pp. 31-44 [PDF]
, 1944 The Catherwood Library and ILR School at Cornell are pleased to again make available an extremely important index of major labor union publications, long out of print. It is Lloyd G. Reynolds and Charles C.
Killingsworth, Charles C +1 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Improving and expanding Medical Subject Headings (MeSH) during times of social change
The International Journal of Information, Diversity, & InclusionIn the summer of 2020, the Latinx Caucus of the Medical Library Association focused on addressing bias in medical subject heading terminologies by establishing the Hispanic/Latinx Inclusive Terminologies Project. Two project teams were formed.
Aidy Weeks +2 more
doaj +1 more source