Results 171 to 180 of about 13,052,428 (347)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Italian clinical practice GRADE-based guidelines on the diagnosis and treatment of overweight and obesity, endorsed by the Italian National Institute of Health. [PDF]

Eat Weight Disord
Barazzoni R, Buscemi S, Busetto L, Sbraccia P, Bo S, Cereda E, Chianelli M, Chiappetta S, Dalle Grave R, de Caro W, Docimo G, Galloro G, Iannone P, Leonetti F, Lisso F, Manca MC, Medea G, Merli M, Moretti AM, Navarra G, Pagotto U, Paolini B, Papa G, Perrotta N, Pession A, Pilone V, Provenzano V, Rizzo CR, Santomauro M, Segura Garcia C, Spandonaro F, Sukkar S, Todisco P, Tuccinardi D, Vania A, Vanzi V, Williams R, Zani I, Ragghianti B, Silverii GA, Belluzzi A, Masulli M, Redini M, Monami M.   +43 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects.

Proceedings of the National Academy of Sciences of the United States of America, 1986
P. T. Fox, M. Raichle
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Social evaluation of skilfulness in Tonkean macaques (Macaca tonkeana) and brown capuchins (Sapajus apella). [PDF]

Anim Cogn
Hirel M, Marziliano M, Meunier H, Rakoczy H, Fischer J, Keupp S.   +5 more
europepmc   +1 more source

Nomadic Subjects : Embodiment and Sexual Difference in Contemporary Feminist Theory

, 1994
R. Braidotti
semanticscholar   +1 more source

The visual word form area: spatial and temporal characterization of an initial stage of reading in normal subjects and posterior split-brain patients.

Brain : a journal of neurology, 2000
L. Cohen, S. Dehaene, L. Naccache, S. Lehéricy, G. Dehaene-Lambertz, M. Hénaff, F. Michèl   +6 more
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Physiological foundation modeling for subclinical disease assessment: a prospective pilot. [PDF]

JAMIA Open
Yuan W, Xu S, Dionisi S, von Herrmann K, Frederick-Dyer K, Cheung-Flynn J, Kennedy C, Flynn CR, Lipnick S.   +8 more
europepmc   +1 more source