Results 161 to 170 of about 47,670 (263)

Therapeutic Potential of Gene‐Modified MSC‐Exos in Insulin Resistance: Mitochondrial Crosstalk and miRNA Regulation

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT Insulin resistance (IR) is the key driver of type 2 diabetes mellitus, metabolic dysfunction‐associated steatotic liver disease, and cardiometabolic disorders. Mesenchymal stem cell‐derived exosomes (MSC‐Exos) as a potent cell‐free alternative can deliver miRNAs, proteins, and mitochondrial regulators to reactivate the IRS1/PI3K/Akt/GLUT4 axis.
Qinghua Jia   +6 more
wiley   +1 more source

Safety and tolerance of oral ketamine: A systematic review

open access: yesPsychiatry and Clinical Neurosciences, Volume 80, Issue 9, Page 730-739, September 2026.
Oral ketamine has gained increasing interest beyond anesthesia, particularly for treatment‐resistant depression, chronic pain, and pediatric procedural sedation. Despite expanding off‐label use, there is no standardized pharmaceutical formulation, and long‐term safety remains uncertain.
Nathalia Novaretti   +4 more
wiley   +1 more source

Safety of S‐acetyl glutathione as an novel food pursuant to Regulation (EU) 2015/2283

open access: yesEFSA Journal, Volume 24, Issue 9, September 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on S‐acetyl glutathione (SAG) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF consists of > 97% (w/w) SAG, which is an acetylated tripeptide (i.e.
EFSA Panel on Nutrition   +25 more
wiley   +1 more source

Assessment of Bioavailability and Related Bioactivity of Hydroxycinnamic Acids. [PDF]

open access: yesCurr Issues Mol Biol
Valkova E   +4 more
europepmc   +1 more source

Efficacy and safety of sublingual cilostazol and dexborneol for the treatment of acute ischaemic stroke: a randomised phase 2 trial in China. [PDF]

open access: yesEClinicalMedicine
Wang Y   +23 more
europepmc   +1 more source

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