ABSTRACT Insulin resistance (IR) is the key driver of type 2 diabetes mellitus, metabolic dysfunction‐associated steatotic liver disease, and cardiometabolic disorders. Mesenchymal stem cell‐derived exosomes (MSC‐Exos) as a potent cell‐free alternative can deliver miRNAs, proteins, and mitochondrial regulators to reactivate the IRS1/PI3K/Akt/GLUT4 axis.
Qinghua Jia +6 more
wiley +1 more source
Route-resolved priority risks of disinfection by-products in indoor pools: the underestimated role of buccal/sublingual exposure for the public and competitive swimmers. [PDF]
Genişoğlu M +3 more
europepmc +1 more source
Safety and tolerance of oral ketamine: A systematic review
Oral ketamine has gained increasing interest beyond anesthesia, particularly for treatment‐resistant depression, chronic pain, and pediatric procedural sedation. Despite expanding off‐label use, there is no standardized pharmaceutical formulation, and long‐term safety remains uncertain.
Nathalia Novaretti +4 more
wiley +1 more source
Near Total Resolution of Severe Refractory Chronic Cough With Low-Dose Sublingual Buprenorphine: Case Report. [PDF]
Streem DW, Benovic J, Anand A.
europepmc +1 more source
Safety of S‐acetyl glutathione as an novel food pursuant to Regulation (EU) 2015/2283
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on S‐acetyl glutathione (SAG) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF consists of > 97% (w/w) SAG, which is an acetylated tripeptide (i.e.
EFSA Panel on Nutrition +25 more
wiley +1 more source
Efficacy of Sublingual Misoprostol Versus Intravenous Tranexamic Acid in Reducing Blood Loss Among Full-Term Pregnant Women Undergoing Primary Lower Segment Caesarean Section: A Randomized Controlled Trial. [PDF]
Basavaraj N, B A, Pushpa K.
europepmc +1 more source
Assessment of Bioavailability and Related Bioactivity of Hydroxycinnamic Acids. [PDF]
Valkova E +4 more
europepmc +1 more source
Efficacy and safety of sublingual cilostazol and dexborneol for the treatment of acute ischaemic stroke: a randomised phase 2 trial in China. [PDF]
Wang Y +23 more
europepmc +1 more source

