Results 121 to 130 of about 1,812,940 (257)

Sublingual Administration of Tacrolimus in Liver Transplant Patient with Intestinal Malabsorption

Indian Journal of Transplantation
Immunosuppressive therapy after liver transplantation typically combines a calcineurin inhibitor, an antimetabolite, and corticosteroids. Tacrolimus, due to its narrow therapeutic margin and variability in blood levels, requires therapeutic drug ...
Aritz Merchán Flores, Mercedes Arenere Mendoza, Irene Navarro Pardo, María Ángeles Allende Bandrés   +3 more
doaj   +1 more source

Comparison of exercise training and repeated hot water immersion on vascular function in overweight older adults

Experimental Physiology, EarlyView.
Abstract Recent studies suggest that heat exposure may benefit cardiovascular health, but in overweight and obese older adults, the chronic effects of heat therapy on artery function are still uncertain. We aimed to compare the effects of 12 weeks (3×/week, 40 min) of aerobic exercise (EXE) to hot water immersion (HWI) and an inactive control group ...
Juliene G. Costa, Joao Carlos Locatelli, Kristanti W. Wigati, Louise H. Naylor, Helen Jones, Andrew Haynes, Daniel J. Green   +6 more
wiley   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

SUBLINGUAL CAPTOPRIL - A PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION

, 1991
In this study we compared the pharmacokinetics and pharmacodynamics of captopril after sublingual and peroral administration. Single 25 mg doses of captopril were administered sublingually and perorally on two different occasions in a randomised cross ...
McElnay, James, Rusk, R., Scott, M.G., Nicholls, D.P., Elborn, J.S., Alfuraih, T.A., Mcmahon, J.   +6 more
core   +2 more sources

A cross-comparative pharmacokinetic study of Klimalanin (ingestion or sublingual intake)

Гинекология, 2013
Beta-alanine (Klimalanin) is generally used for the treatment and prevention of vasomotor disturbances (hot flushes) in menopausal period. This paper presents the results of a comparative analysis of the beta-alanine pharmacokinetics with a single ...
I S Yurghel, O A Limanova, T B Siling, I Yu Torshin, A N Gromov, A Yu Volkov, E Yu Egorova, O A Gromova   +7 more
doaj  

Microcirculatory depth of focus measurement shows reduction of tissue edema by albumin resuscitation in burn patients

Journal of Intensive Medicine
Background: Severe burns induce volume shifts via capillary leaks, eventually requiring massive fluid resuscitation and promoting tissue edema. Albumin may help to mitigate the edema, thereby improving perfusion.
Olcay Dilken, Annemieke Dijkstra, Göksel Güven, Bülent Ergin, Nicole Trommel, Margriet E. van Baar, Helma WC Hofland, Can Ince, Cornelis H. van der Vlies   +8 more
doaj   +1 more source

Nanomedicine for the Treatment of Pediatric Type 2 Diabetes: Progress, Challenges, and Translational Perspectives

Advanced Therapeutics, Volume 9, Issue 9, September 2026.
Overview of pharmaceutical nanocarriers in diabetes, illustrating applications of nanotechnology including enhanced drug and targeted drug delivery and nanosensors for glucose monitoring and diagnosis. ABSTRACT Pediatric type 2 diabetes mellitus (T2DM) is rapidly emerging as a critical global health concern, driven largely by rising childhood obesity ...
Nnamdi Ikemefuna Okafor, Bukosi Baloyi, Yahya E. Choonara   +2 more
wiley   +1 more source

175.KN.11 SUBLINGUAL GLAND

, 1964
a. Sublingual gland b. Submandibular gland c. Lingual nerve d. Hypoglossal nerve (XII) e. Glossopharyngeal nerve (IX) f. Geniohyoid muscle g. Hyoglossus muscle h. Styloglossus muscle i.
Brune, E.
core  

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, Volume 13, Issue 50, 7 September 2026.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Sublingual vaccination

, 2011
The sublingual route has been used for many years to deliver drugs and small molecules to the bloodstream. Surprisingly, the potential of this route for delivering vaccines has received very little if any attention until recently.
Holmgren, Jan,
core