Results 101 to 110 of about 1,898,806 (256)

Establishing Time Course of Testosterone Using Saliva After a Sublingual Administration: A Pilot Study

, 2017
Sublingual administration of 0.05 mg of testosterone has been found to be a safe and effective method to induce higher testosterone levels in females.
Strenth, Chance
core  

Subcutaneous Allergen Immunotherapy With Thermosensitive Hydrogel and Recombinant Birch Pollen Allergen Variant, a Randomised Controlled Trial

Clinical &Experimental Allergy, EarlyView.
A Phase 1, randomised, placebo‐controlled, dose‐escalation trial was performed with 30 birch pollen allergic subjects treated with DM‐101PX, that contains a recombinant hypoallergenic variant of Bet v 1 formulated with poloxamer 338 thermosensitive hydrogel.
Anna Nilson, Patricia Couroux, Jaana Haka, Silja Halme, Pekka Mattila, R. J. Joost van Neerven, Rolien Pels‐Rijcken, Janneke Ruinemans‐Koerts, Yvonne Schmidt‐Hieltjes, Anne Marie Salapatek, Kati Sallinen, Kristiina Takkinen, Daphne Tsitoura, Dirk‐Jan Opstelten, Juha Rouvinen   +14 more
wiley   +1 more source

A Phase I Pharmacokinetic and Bioavailability Study of a Sublingual Fentanyl Wafer in Healthy Volunteers

, 2012
Background: The sublingual administration of opioids is a simple and noninvasive method that provides rapid analgesia. In this phase I study we investigated the pharmacokinetics and bioavailability of a fentanyl wafer in healthy volunteers. The principal
Bruce Sunderland (677942), Stephen Lim (149062), Stephan Schug (16942933), Michael Paech (23361046), Yandi Liu (8981615)   +4 more
core   +2 more sources

Serum Estradiol Concentrations With Estradiol 0.06% Gel in Transgender and Gender‐Diverse Adults

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Transgender and gender‐diverse individuals undergoing estradiol therapy for gender affirmation are typically treated with oral or transdermal estradiol, with transdermal estradiol recommended for those aged > 45 years. There are limited data evaluating estradiol gel in gender‐affirming hormone therapy regimens. We aimed to assess the
Raquel A. Maggacis, Ada S. Cheung, Brendan J. Nolan   +2 more
wiley   +1 more source

Introduction to pharmacology, and routes of drugs administration and absorption [PDF]

, 2017
This eChapter has an introduction to pharmacology and drug nomenclature followed by a detailed discussion of routes of administration starting with oral administration (with absorption from the gastrointestinal tract, and first pass liver metabolism ...
Doggrell, Sheila
core  

A 3D atlas of the trigeminal nerve and its relevance for comparative studies of the masticatory apparatus in rodents

Journal of Anatomy, EarlyView.
The trigeminal nerve of the rat (Rattus norvegicus) and its relationship with different masticatory muscles. dig, digastric nerve; ep, external pterygoid nerve; ip, internal pterygoid nerve; maadm, branch of the masseteric nerve for the anterior deep masseter; mapdm, branches of the masseteric nerve for the posterior deep masseter; masm, branch of the ...
Lionel Hautier, Marcos Angelo Alves, Léa Da Cunha, Benoit Moison, Ludovic Besson, Pierre‐Henri Fabre   +5 more
wiley   +1 more source

Individualized Oral Health Care for Dysphagic, Care‐Dependent Patients With Acquired Brain Injury: An Exploratory Predefined Subgroup Analysis of a Cluster Nonrandomized Controlled Trial

Journal of Oral Rehabilitation, EarlyView.
This graphical abstract summarizes an exploratory predefined subgroup analysis of dysphagic, care‐dependent adults with acquired brain injury undergoing inpatient neurorehabilitation. Three wards implemented standard oral care, while three wards implemented the structured individualized MOHIT protocol.
Mohit Kothari
wiley   +1 more source

Deposition of a model substance, Tc E-HIDA, in the oral cavity after administration of lozenges, chewing gum and sublingual tablets

, 1990
The deposition and clearance of a model substance, Tc E-HIDA, in the oral cavity/upper oesophagus and in the stomach after administration of lozenges, chewing gum and sublingual tablets has been followed by gamma scintigraphy in a group of healthy male ...
Frier, M., Rasmussen, S.N., Wilding, I.R., Melia, C.D., Davis, S.S., Andersen, C., Christrup, Lona Louring, Washington, N.   +7 more
core   +1 more source

Pharmacokinetics of Buccally Administered Cannabidiol and Oral Carprofen During Single‐ and Repeated‐Dose Administration in Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Cannabidiol (CBD) is increasingly used as an adjunct treatment for chronic pain in dogs, but information on repeated‐dose pharmacokinetics and potential interactions with commonly used analgesics remains limited. This study evaluated the pharmacokinetics of buccally administered CBD, its major metabolites, and orally administered carprofen in ...
Tilen Vake, Katerina Tomsič, Žiga Žgank, Mihaela Klasić, Janja Babič, Zlatka Bajc, Jožica Dolenc, Gabrijela Tavčar Kalcher, Odon Planinšek, Tomaž Snoj   +9 more
wiley   +1 more source

SUBLINGUAL BUPRENORPHINE VS MIDAZOLAM FOR PREMEDICATION IN CHILDREN

Journal of Research in Medical Sciences, 2000
Background. Preanesthetic medication may reduce the risks of adverse psychological and physiological sequel of induction in children. Administration of premedication by sublingual route may provide the best compromise because of relatively rapid ...
V.A HASANI, A AMANNI, S JALALI MOTLAGH
doaj