Results 81 to 90 of about 1,898,806 (256)
SUBLINGUAL CAPTOPRIL - A PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION
, 1991 In this study we compared the pharmacokinetics and pharmacodynamics of captopril after sublingual and peroral administration. Single 25 mg doses of captopril were administered sublingually and perorally on two different occasions in a randomised cross ...
McElnay, James +6 more
core +2 more sources
Development of a sublingual allergy vaccine for grass pollinosis
, 2010 Franco Frati1,2, Silvia Scurati1, Paola Puccinelli1, Marie David3, Cecile Hilaire4, Maurizio Capecce4, Francesco Marcucci2, Cristoforo Incorvaia51Medical and Scientific Department, Stallergenes, Milan, Italy; 2University Department of Medical and ...
Silvia Scurati +3 more
core
Allergy, EarlyView.HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.
Varsha Dwivedi +12 more
wiley +1 more source
Route of Allergen Immunotherapy: A Global Look Into Physicians' Motivations
Allergy, EarlyView.Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.
Carmen Vidal +42 more
wiley +1 more source
Allergy, EarlyView.This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić +13 more
wiley +1 more source
Perioperative sublingual levodopa in Parkisnon's Disease: A useful alternative!
Indian Journal of Anaesthesia, 2017 Timely administration of dopamine agonists is of the essence in Parkinson's disease. The perioperative period especially for abdominal surgeries under general anaesthesia poses a challenge to oral drug administration.
Pritee H Bhirud, Jalpa Arvind Kate
doaj +1 more source
Sublingual immunotherapy: administration, dosages, use.
International journal of immunopathology and pharmacology, 2009 Allergen extracts for sublingual immunotherapy (SLIT) are currently marketed by several manufacturers, with administration schedules and amount of allergen(s) quite variable in the different products, although almost all are standardized biologically or immunologically.
Frati, F +7 more
openaire +2 more sources
The pharmacokinetics of clotiazepam after oral and sublingual administration to volunteers
, 1989 The single dose pharmacokinetics of 5 mg clotiazepam drops, oral tablets, and sublingual tablets were studied in a cross-over study in 6 healthy volunteers (median age 28 yr). The formulations had similar systemic availability.
M. Broggini +5 more
core +1 more source
Allergy, EarlyView.ABSTRACT Allergen immunotherapy (AIT) has been acknowledged as the only disease‐modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study results may vary substantially.
Roy Gerth van Wijk +10 more
wiley +1 more source
Frontiers in Immunology, 2017 The need for more effective influenza vaccines is highlighted by the emergence of novel influenza strains, which can lead to new pandemics. There is a growing population of susceptible subjects at risk for severe complications of influenza, such as the ...
Thomas Ebensen +12 more
doaj +1 more source