Results 81 to 90 of about 1,812,940 (257)

Pharmacokinetics and pharmacodynamics of detomidine following sublingual administration to horses

open access: yes, 2011
Objective—To characterize pharmacokinetics and pharmacodynamics of detomidine gel administered sublingually in accordance with label instructions to establish appropriate withdrawal guidelines for horses before competition.
Scott D. Stanley   +1 more
core   +1 more source

Angiogenic biomarker concentrations and their relation to coronary atherosclerosis in women with a history of preeclampsia: Findings from the CPH‐PRECIOUS study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
This study demonstrates that women with prior preeclampsia had significantly higher concentrations of PlGF when CT‐assessed coronary atherosclerosis was present years following the index pregnancy, whereas no difference was found for concentrations of sFlt‐1.
Signe Højstrup Bessing   +11 more
wiley   +1 more source

Perioperative sublingual levodopa in Parkisnon's Disease: A useful alternative!

open access: yesIndian Journal of Anaesthesia, 2017
Timely administration of dopamine agonists is of the essence in Parkinson's disease. The perioperative period especially for abdominal surgeries under general anaesthesia poses a challenge to oral drug administration.
Pritee H Bhirud, Jalpa Arvind Kate
doaj   +1 more source

Sublingual immunotherapy: administration, dosages, use.

open access: yesInternational journal of immunopathology and pharmacology, 2009
Allergen extracts for sublingual immunotherapy (SLIT) are currently marketed by several manufacturers, with administration schedules and amount of allergen(s) quite variable in the different products, although almost all are standardized biologically or immunologically.
Frati, F   +7 more
openaire   +2 more sources

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Cutting-edge research frontiers in oral cavity vaccines for respiratory diseases: a roadmap for scientific advancement

open access: yesFrontiers in Cellular and Infection Microbiology
Intramuscular vaccines present limitations in eliciting robust mucosal immunity and preventing respiratory pathogens transmission. Sublingual vaccine administration offers promising advantages, including interconnected mucosal protection.
Erwan Sallard   +3 more
doaj   +1 more source

DEVELOPMENT, EVALUATION AND APPLICATION OF INSULIN SOLUTION AND FILM DOSAGE FORMS FOR SUBLINGUAL ADMINISTRATION [PDF]

open access: yes, 2020
The major barrier for sublingual absorption of large molecules like insulin is low permeability owing to the hydrophilic nature of insulin. One approach to overcome this barrier is to sublingually co-administer insulin with permeation enhancers (HPβCD ...
Paprikar, Anuja
core  

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Mucosal Administration of Cycle-Di-Nucleotide-Adjuvanted Virosomes Efficiently Induces Protection against Influenza H5N1 in Mice

open access: yesFrontiers in Immunology, 2017
The need for more effective influenza vaccines is highlighted by the emergence of novel influenza strains, which can lead to new pandemics. There is a growing population of susceptible subjects at risk for severe complications of influenza, such as the ...
Thomas Ebensen   +12 more
doaj   +1 more source

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