Results 61 to 70 of about 1,812,940 (257)

Current status of sublingual immunotherapy in the United States

World Allergy Organization Journal, 2014
Sublingual immunotherapy (SLIT) use in the United States to date has been limited, despite common use and demonstrated efficacy elsewhere in the world.
Shelby Elenburg, Michael S. Blaiss
doaj   +1 more source

Rectal and sublingual administration of tacrolimus: a single-dose pharmacokinetic study in healthy volunteers

, 2014
Aims: The immunosuppressant tacrolimus is usually administered orally. When this is not feasible, other routes of administration may be useful. Previous research suggested that tacrolimus may be applied sublingually or rectally.
Stifft, Frank, Christiaans, Maarten, Vanmolkot, F., Scheffers, I., Vanmolkot, Floris, Stifft, F., Neef, C., Scheffers, Ingrid, Ingrid Scheffers, Van Bortel, Lucas, Cees Neef, Floris Vanmolkot, Neef, Cees, van Bortel, L., Maarten Christiaans, Christiaans, M., Frank Stifft, Luc van Bortel   +17 more
core   +1 more source

Bioactive Gold Plasmonic Interfaces Meet Artificial Intelligence: Advancing Saliva‐Based Surface‐Enhanced Raman Spectroscopy Diagnostics

Small, EarlyView.
ABSTRACT Bioactive gold plasmonic nanostructures are enabling non‐invasive saliva diagnostics by amplifying weak Raman signals and converting complex biofluid chemistry into information‐rich spectral fingerprints. This Review examines saliva‐based Raman and surface‐enhanced Raman spectroscopy (SERS) integrated with artificial intelligence (AI) from a ...
Ajitesh Dhal, Ana Elena Aviña, Nguyen Le Thanh Hang, Pei‐Wen Peng, Cheng‐Jen Chang, Tzu‐Sen Yang   +5 more
wiley   +1 more source

Transition between subcutaneous and sublingual allergen immunotherapy: Recommendations of the Brazilian Association of Allergy and Immunology (ASBAI)

Journal of Allergy and Clinical Immunology: Global
The use of allergen immunotherapy (AIT) in Brazil has specific regional conditions owing to the pattern of allergen sensitization, as well as to genetic, socioeconomic, and cultural characteristics.
Fernando Monteiro Aarestrup, MD, PhD, Ernesto Akio Taketomi, MD, PhD, Clóvis Eduardo Santos Galvão, MD, PhD, Gil Bardini Alves, MD, MSc, Geórgia Véras de Araújo Gueiros Lira, MD, PhD, Marcos Reis Gonçalves, MD, MSc, Mariana Graça Couto Miziara, MD, Sidney Souteban Maranhão Casado, MD, Veridiana Aun Rufino Pereira, MD, PhD, Dirceu Solé, MD, PhD, Ekaterini Simoes Goudouris, MD, PhD, Fabio Chigres Kuschnir, MD, PhD   +11 more
doaj   +1 more source

Craving and personal functioning as mediators of extended‐release buprenorphine efficacy: A four‐way decomposition analysis from a randomised trial

Addiction, EarlyView.
Abstract Aims To investigate whether the treatment effect of extended‐release buprenorphine (BUP‐XR) on opioid‐free days in opioid use disorder (OUD) is mediated by reductions in opioid craving and improvements in personal functioning. Design and setting Exploratory causal mediation analysis using VanderWeele's four‐way decomposition framework in a 24 ...
John Marsden, Mike Kelleher, Fiona Cowden, Edward Day, Jonathan Dewhurst, Rachel Evans, Eilish Gilvarry, Natalie Lowry, Luke Mitcheson, Robert Murray, Sophie Quarshie, Zoë Hoare   +11 more
wiley   +1 more source

Clinical applications of wearable devices for individuals with at‐risk substance use and substance use disorders: A systematic review

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Managing substance use disorders (SUDs) is limited by the lack of longitudinal clinical data during active use and recovery. Wearable devices may help address this gap by capturing physiological and behavioral data in real‐world settings.
Alexandra Sas, Matthew E. Sloan, Yaoyi Xing, Ethan Kim, Dhvani Mehta, Anna Mouzenian, Lena C. Quilty, Jeffrey D. Wardell, Shannon Lange, Daniel Felsky, Victor M. Tang   +10 more
wiley   +1 more source

Opportunities to harmonize postpartum hemorrhage recommendations

International Journal of Gynecology &Obstetrics, EarlyView.
George Justus Hofmeyr, N. F. Moran, S. R. Fawcus, A. D. Weeks, S. Arulkumaran   +4 more
wiley   +1 more source

Kinetics of Antibody Responses and Effector Cell Sensitivity After High Dose Birch Extract Nasal Challenge

Allergy, EarlyView.
High‐dose birch‐extract nasal challenge induced synchronous peaks at 4 weeks in serum specific IgE (sIgE) and basophil sensitivity. Mast cell sensitivity via tSPT and sIgG1 and sIgG4 responses peaked later, at 6–8 weeks. Preseasonal allergen exposure attenuated seasonal sIgE increase and prevented further rise in tSPT sensitivity.
N. J. Campion, S. Villazala‐Merino, C. Morgenstern, L. Nemec, V. Stanek, A. Tu, M. Zghaebi, J. Toth, R. Fröschl, T. Perkmann, M. Bastl, K. Gangl, S. Schneider, H. Breiteneder, R. Ristl, M. Focke‐Tejkl, R. Valenta, V. Niederberger‐Leppin, J. Eckl‐Dorna   +18 more
wiley   +1 more source

Investigating the Analgesic Effect of Sublingual Glycerol Trinitrate (GTN) Spray as an Alternative Treatment in Renal Colic Pain: A Triple-Blinded Randomized Controlled Trial

Acta Medica Iranica
Renal colic, a severe pain caused by renal and urethral calculi, causes millions of patients to visit the emergency department (ED) worldwide each year.
Paria Sadat Ramezany, Mohammed Ali Shadram, Ahmad Reza Dehpour, Razieh Mohammad Jafari, Morteza Saeedi, Mehrad Aghili, Javad Seyedhosseini   +6 more
doaj   +1 more source

Preventive Application of House Dust Mite‐Sublingual Immunotherapy Induces Blocking Antibodies in Sensitized Preschool Children

Allergy, EarlyView.
HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.
Varsha Dwivedi, Klara Schmidthaler, Hilal Demir, Justyna Sieber, René Gaupmann, Livia Mia Gona‐Höpler, Christina Bannert, Saskia Gruber, Eleonora Dehlink, Thomas Eiwegger, Alexandra Graf, Barbara Bohle, Zsolt Szépfalusi   +12 more
wiley   +1 more source