Results 71 to 80 of about 1,898,806 (256)

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Efficacy and Safety of Cannabis Derivates and Their Synthetic Analogs. Overview of Systematic Reviews

Phytotherapy Research, EarlyView.
ABSTRACT The use of medicinal products derived from cannabis and its synthetic analogues has grown in recent years for various health conditions, which led to an increase in systematic reviews (SR) on the topic. The objective of this overview was to identify, synthesize, and critically appraise the evidence from SR on the benefits and harms of cannabis
Rafael Leite Pacheco, Daniela Fortunato Rêgo, Carolina de Oliveira Cruz Latorraca, Marco Aurelio de Carvalho Nascimento, André Bastos Daher, Rachel Riera   +5 more
wiley   +1 more source

Investigating the Analgesic Effect of Sublingual Glycerol Trinitrate (GTN) Spray as an Alternative Treatment in Renal Colic Pain: A Triple-Blinded Randomized Controlled Trial

Acta Medica Iranica
Renal colic, a severe pain caused by renal and urethral calculi, causes millions of patients to visit the emergency department (ED) worldwide each year.
Paria Sadat Ramezany, Mohammed Ali Shadram, Ahmad Reza Dehpour, Razieh Mohammad Jafari, Morteza Saeedi, Mehrad Aghili, Javad Seyedhosseini   +6 more
doaj   +1 more source

FORMULATION AND EVALUATION OF SUBLINGUAL TABLET FOR NARATRIPTA [PDF]

, 2014
Naratriptan is used for the treatment of migraine. Formulation and Evaluation of sublingual tablets of Naratriptan for pre and post Compression parameters was undertaken.  The tablets were prepared by direct compression method using super disintegrates.
Upadhyay, Umesh, Makwana, Priti, Brahmbhatt, Hiral, Brahmbhatt, Hardik, Patel, Krishna, Jain, Hitesh, Chauhan, Nimisha   +6 more
core   +1 more source

Network mapping of MRI‐defined anatomical invasion phenotypes for prognostic stratification in oral tongue squamous cell carcinoma

VIEW, EarlyView.
Abstract The AJCC/UICC clinical T staging for oral tongue squamous cell carcinoma (OTSCC) primarily relies on radiological depth of invasion (rDOI) and may not capture complex oral structure invasion (OSI). Therefore, we developed a magnetic resonance imaging (MRI)‐based risk stratification system integrating rDOI and OSI and explored the association ...
Jie Pan, Sisi Huang, Fei Xie, Hui Xie, Zhiying Liang, Guangying Ruan, Shuqi Li, Chao Luo, Fengze Wu, Haojiang Li, Lizhi Liu, Wenjie Huang   +11 more
wiley   +1 more source

Comparison of sublingual and vaginal misoprostol for second-trimester pregnancy terminations.

Journal of Family and Reproductive Health, 2014
Objective: Comparing sublingual and vaginal misoprostol in second trimester pregnancy termination. Materials and methods: In this study 268 women at 12-24 weeks of gestation candidate for pregnancy termination were enrolled.
Forozan Milani, Seyede Hajar Sharami, Saeedeh Arjmandi   +2 more
doaj  

Comparison of sequential vaginal and sublingual misoprostol after a vaginal loading dose for second-trimester abortion

Taiwanese Journal of Obstetrics & Gynecology, 2017
Objective: To evaluate the effects of sequential vaginal and sublingual misoprostol after a vaginal loading dose for second-trimester abortion. Materials and methods: From January 2006 to December 2011, 173 women received an 800-μg vaginal loading dose ...
Ming-Chao Huang, Ching-Hung Hsieh, Jian-Pei Huang, Hsiu-Ting Tsai, Maw-Sheng Lee   +4 more
doaj   +1 more source

A comparison of sublingual with vaginal administration of misoprostol for induction of labor at term [PDF]

, 2017
Background: To compare the efficacy and safety of sublingual route of misoprostol with vaginal route of administration.Methods: This study was conducted at Department of Obstetrics and Gynecology, Medical College, Baroda, Gujarat, India.
Purvi K. Patel, Patel, Purvi K., Monika D. Akare, Akare, Monika D.   +3 more
core   +1 more source

Critical constraints to ecological buffering in a rapidly changing Arctic: A long‐term seabird study

Journal of Animal Ecology, EarlyView.
Drawing on two decades of research in East Greenland, this study shows that little auks, key seabird indicators of Arctic ecosystem health, can adapt to rapid environmental change through behavioural flexibility. However, increasing storms and mercury pollution are pushing resilience to its limits, providing an early warning of broader Arctic ...
David Grémillet, Françoise Amélineau, Ann M. A. Harding, Jérôme Fort   +3 more
wiley   +1 more source

Kinetics of Antibody Responses and Effector Cell Sensitivity After High Dose Birch Extract Nasal Challenge

Allergy, EarlyView.
High‐dose birch‐extract nasal challenge induced synchronous peaks at 4 weeks in serum specific IgE (sIgE) and basophil sensitivity. Mast cell sensitivity via tSPT and sIgG1 and sIgG4 responses peaked later, at 6–8 weeks. Preseasonal allergen exposure attenuated seasonal sIgE increase and prevented further rise in tSPT sensitivity.
N. J. Campion, S. Villazala‐Merino, C. Morgenstern, L. Nemec, V. Stanek, A. Tu, M. Zghaebi, J. Toth, R. Fröschl, T. Perkmann, M. Bastl, K. Gangl, S. Schneider, H. Breiteneder, R. Ristl, M. Focke‐Tejkl, R. Valenta, V. Niederberger‐Leppin, J. Eckl‐Dorna   +18 more
wiley   +1 more source