Results 201 to 210 of about 1,898,806 (256)

Pharmacokinetic aspects of the sublingual administration of vincamine

Biopharmaceutics & Drug Disposition, 1990
AbstractThe sublingual absorption of vincamine used as tracer occurs in two successive absorption steps: true sublingual absorption and absorption in the gastrointestinal tract of the drug dissolved in the saliva and not absorbed through the buccal mucosa. This is confirmed by a pharmacokinetic study and simulation. These two successive absorptions can
J M, Aiache, M C, Delatte, P P, Leblanc, J P, Kantelip, R, Gomeni, J L, Steimer   +5 more
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Hypoxemia following the administration of sublingual nitroglycerin

The American Journal of Medicine, 1978
Nitroglycerin, 0.6 mg sublingually, was given to 27 nonasthmatic subjects with varying degrees of airways dysfunction to determine the effect on arterial oxygenation. In six normal subjects, the partial pressure of oxygen in arterial blood (Pao2) transiently decreased by 9 mm Hg (p less than 0.05) and in eight subjects with only small airways ...
C A, Hales, D, Westphal
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Ocular hypotensive effect of sublingual administration of timolol

International Ophthalmology, 1997
A randomized clinical, trial to assess ocular hypotensive effect of sublingual administration of timolol was performed.Seventeen (9 male, 8 female; age range 45 to 68 years) with bilateral ocular hypertension were selected for the study. Each patient was evaluated with regard to IOP, arterial blood pressure and heart rate before and after each of the ...
QUARANTA, Luciano, PASQUINI L., CASSAMALI M., HAURANIEH N., GANDOLFO, Enrico, QUARANTA C. A.   +5 more
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The sublingual administration of curare.

California medicine, 2003
A new method of administering d-tubocurarine transmucosally by sublingual pellets (and also by rectal suppository) was used in 100 patients. In therapeutic dosage of 6 to 12 mg., it was found to be non-toxic and very effective in relieving pain due to acute and chronic muscle spasm.
W B, NEFF, H, MAYER
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Sublingual Administration of Desmopressin

American Journal of Diseases of Children, 1987
A 3-month-old child with bilateral cleft lip and palate and holoprosencephaly was hospitalized after he developed diabetes insipidus presumably due to hypothalamic dysfunction. He was initially treated with subcutaneous vasopressin injection but was switched to therapy with desmopressin acetate (DDAVP) before discharge.
M S, Kappy, E, Sonderer
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Symptomatic bradycardia following the administration of sublingual nitroglycerin

The American Journal of Emergency Medicine, 1993
A case of severe bradycardia with junctional escape immediately following sublingual nitroglycerin is described. Bradycardia is a rare, but well-documented, complication of nitroglycerin and is often reported in the setting of myocardial ischemia or infarction.
R, Buckley, R, Roberts
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Arterial hypoxemia following the administration of sublingual nitroglycerin

American Heart Journal, 1978
The effect of nitroglycerin on arterial blood gases and cardiovascular hemodynamics were studied in patients with coronary artery disease. In 13 premedicated patients blood gases and cardiovascular hemodynamics were studied before and 10 minutes after sublingual nitroglycerin (0.6 mg).
E A, Kopman, G R, Weygandt, S, Bauer, T B, Ferguson   +3 more
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Myocardial Infarction following Administration of Sublingual Ergotamine

Chest, 1982
Ergotamine is commonly used in the treatment of migraine headache. Since migraine may be associated with variant angina, some patients with migraine may develop coronary ischemia following therapy with ergotamine. We describe a young woman with migraine who had two myocardial infarctions following low dose sublingual ergotamine.
L S, Klein, R J, Simpson, R, Stern, J C, Hayward, J R, Foster   +4 more
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Alprazolam Kinetics Following Sublingual and Oral Administration

Journal of Clinical Psychopharmacology, 1987
Thirteen healthy volunteers received 1 mg of alprazolam, as the commercially available oral tablet, by sublingual and oral routes on two occasions in random sequence. Plasma alprazolam concentrations during 48 hours after each dose were measured by electron-capture gas-liquid chromatography.
J M, Scavone, D J, Greenblatt, R I, Shader   +2 more
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Sublingual administration of warfarin: a novel form of delivery

Vascular Medicine, 2008
Abstract Current therapy for venous thromboembolism (VTE) includes the initiation of short acting parenteral agents, heparin, low-molecular-weight heparin, or fondaparinux, with subsequent conversion to oral warfarin therapy for the duration of anticoagulation. We present two patients who required long-term anticoagulation for VTE but
Susan, Batke-Hastings, Teresa L, Carman
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