Results 201 to 210 of about 1,812,940 (257)

Dextromoramide pharmacokinetics following sublingual administration

Palliative Medicine, 1996
The extent of absorption and other pharmacokinetic parameters of dextromoramide following sublingual administration were assessed in five patients receiving chronic opioid analgesia. The use of the standard 5 mg tablet formulation was associated with negligible absorption in two patients, a prolonged time to peak concentration in the other three and ...
Jones, Terry E., Morris, Raymond G., Saccoia, N. C., Thorne, David   +3 more
exaly   +3 more sources

Sublingual and buccal drug administration in medical emergencies

Medicina Clínica (English Edition)
Drug administration is crucial to achieve effective therapeutic drug outcomes. In medical emergencies, it is particularly convenient to use drugs that could be administered as an alternative to traditional routes (as oral or intravenous routes), that are not always suitable in these situations. Thus, sublingual and buccal routes offer an alternative to
Joan Ramon, Roma, Pedro, Castro Rebollo, Carla, Bastida   +2 more
exaly   +3 more sources

Sublingual administration improves systemic exposure of tacrolimus in kidney transplant recipients: comparison with oral administration

European Journal of Clinical Investigation, 2016
Tacrolimus (TCR) is an immunosuppressive drug used by oral administration. Intravenous (IV) TCR administration is required under conditions of gastrointestinal diseases or abdominal surgery at the onset of paralytic ileus.
Tarantino Giovanni, Massimo Sabbatini, Michele Santangelo   +2 more
exaly   +2 more sources

Furosemide: Sublingual Administration

Hospital Pharmacy, 2008
Off-Label Drug Uses — This Hospital Pharmacy feature is extracted from Off-Label DrugFacts, a quarterly publication available from Wolters Kluwer Health. Off-Label DrugFacts is a practitioner-oriented resource for information about specific FDA-unapproved drug uses.
Joyce Generali, Dennis J. Cada
openaire   +1 more source

Pharmacokinetic aspects of the sublingual administration of vincamine

Biopharmaceutics & Drug Disposition, 1990
AbstractThe sublingual absorption of vincamine used as tracer occurs in two successive absorption steps: true sublingual absorption and absorption in the gastrointestinal tract of the drug dissolved in the saliva and not absorbed through the buccal mucosa. This is confirmed by a pharmacokinetic study and simulation. These two successive absorptions can
J M, Aiache, M C, Delatte, P P, Leblanc, J P, Kantelip, R, Gomeni, J L, Steimer   +5 more
openaire   +2 more sources

Hypoxemia following the administration of sublingual nitroglycerin

The American Journal of Medicine, 1978
Nitroglycerin, 0.6 mg sublingually, was given to 27 nonasthmatic subjects with varying degrees of airways dysfunction to determine the effect on arterial oxygenation. In six normal subjects, the partial pressure of oxygen in arterial blood (Pao2) transiently decreased by 9 mm Hg (p less than 0.05) and in eight subjects with only small airways ...
C A, Hales, D, Westphal
openaire   +2 more sources

Ocular hypotensive effect of sublingual administration of timolol

International Ophthalmology, 1997
A randomized clinical, trial to assess ocular hypotensive effect of sublingual administration of timolol was performed.Seventeen (9 male, 8 female; age range 45 to 68 years) with bilateral ocular hypertension were selected for the study. Each patient was evaluated with regard to IOP, arterial blood pressure and heart rate before and after each of the ...
QUARANTA, Luciano, PASQUINI L., CASSAMALI M., HAURANIEH N., GANDOLFO, Enrico, QUARANTA C. A.   +5 more
openaire   +3 more sources

The sublingual administration of curare.

California medicine, 2003
A new method of administering d-tubocurarine transmucosally by sublingual pellets (and also by rectal suppository) was used in 100 patients. In therapeutic dosage of 6 to 12 mg., it was found to be non-toxic and very effective in relieving pain due to acute and chronic muscle spasm.
W B, NEFF, H, MAYER
openaire   +1 more source

Sublingual Administration of Desmopressin

American Journal of Diseases of Children, 1987
A 3-month-old child with bilateral cleft lip and palate and holoprosencephaly was hospitalized after he developed diabetes insipidus presumably due to hypothalamic dysfunction. He was initially treated with subcutaneous vasopressin injection but was switched to therapy with desmopressin acetate (DDAVP) before discharge.
M S, Kappy, E, Sonderer
openaire   +2 more sources

Symptomatic bradycardia following the administration of sublingual nitroglycerin

The American Journal of Emergency Medicine, 1993
A case of severe bradycardia with junctional escape immediately following sublingual nitroglycerin is described. Bradycardia is a rare, but well-documented, complication of nitroglycerin and is often reported in the setting of myocardial ischemia or infarction.
R, Buckley, R, Roberts
openaire   +2 more sources