Results 21 to 30 of about 1,898,806 (256)

Population pharmacokinetic analysis of apomorphine sublingual film or subcutaneous apomorphine in healthy subjects and patients with Parkinson’s disease

open access: yesClinical and Translational Science, 2021
Apomorphine is an on‐demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD). A joint parent‐metabolite population pharmacokinetic (PK) model characterized apomorphine and apomorphine‐sulfate following administration of apomorphine ...
Felix Agbo   +6 more
doaj   +1 more source

Sublingual Tablets and the Benefits of the Sublingual Route of Administration

open access: yesJournal of Pharmaceutical Research, 2017
Purpose : Sublingual drug delivery can be an alternative and better route when compared to oral drug delivery as sublingually administered dosage forms bypass hepatic metabolism. A rapid onset of pharmacological effect is often desired for some drugs, especially those used in the treatment of acute disorders. Sublingual tablets disintegrate rapidly and
Arshad Bashir Khan   +2 more
openaire   +1 more source

Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine [PDF]

open access: yes, 2013
Vaccine compositions that may be administered to a subject via the buccal and/or sublingual mucosa are provided. Methods for administration and preparation of such vaccine compositions are also provided.Board of Regents, University of Texas ...
Croyle, Maria A.   +2 more
core   +1 more source

Sublingual Vaccination with Live Influenza Virus Induces Better Protection Than Oral Immunization in Mice

open access: yesLife, 2022
Both sublingual (SL) and oral vaccine administration modalities are convenient, easy, and safe. Here, we have investigated the differences in vaccine efficacy that are induced by oral and sublingual immunization with live influenza virus (A/Hong Kong/1 ...
Jie Mao   +5 more
doaj   +1 more source

Effect of physicochemical properties on sublingual absorption

open access: yes, 2023
Oral mucosal administration of drugs such as sublingual, supralingual or buccal are the preferred route when a drug exhibits large first pass effect after oral delivery.
Sharma, Pramila   +2 more
core   +1 more source

The combination route versus sublingual and vaginal misoprostol for the termination of 13 to 24 week pregnancies: A randomized clinical trial

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2015
Objective: The goal of this study was to compare the effectiveness of misoprostol via sublingual and vaginal administration versus the combination route in the termination of 13 to 24 week pregnancies.
Fatemeh Rahimi-Sharbaf   +6 more
doaj   +1 more source

Evaluation of the sublingual route for administration of influenza H5N1 virosomes in combination with the bacterial second messenger c-di-GMP. [PDF]

open access: yesPLoS ONE, 2011
Avian influenza A H5N1 is a virus with pandemic potential. Mucosal vaccines are attractive as they have the potential to block viruses at the site of entry, thereby preventing both disease and further transmission.
Gabriel Kristian Pedersen   +6 more
doaj   +1 more source

Debut of Gastroesophageal Reflux Concomitant with Administration of Sublingual Immunotherapy [PDF]

open access: yes, 2017
Gastroesophageal reflux disease (GORD) is an often debilitating condition characterised by retrograde flow of content from stomach into the oesophagus, where the low pH of the stomach acid irritates the mucosa of the oesophagus.
Jacob Juel, Juel, J.
core   +1 more source

Anticancer Effects of Sublingual Type I IFN in Combination with Chemotherapy in Implantable and Spontaneous Tumor Models

open access: yesCells, 2021
Salivary gland tumors are a heterogeneous group of neoplasms representing less than 10% of all head and neck tumors. Among salivary gland tumors, salivary duct carcinoma (SDC) is a rare, but highly aggressive malignant tumor resembling ductal breast ...
Maria Ciccolella   +16 more
doaj   +1 more source

Sublingual Drug Delivery Systems- Faster Therapeutic Action Dosage Forms [PDF]

open access: yes, 2019
Sublingual means “under the tongue” refers to administrating substances through mouth such that the substance is absorbed rapidly via blood vessels under the tongue.
Sarath Chandra, T., Santosh Kumar, Rada
core   +1 more source

Home - About - Disclaimer - Privacy