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Journal of Allergy and Clinical Immunology, 2001 Recent claims have been made that sublingual immunotherapy (SLIT) may be a viable alternative to injection immunotherapy (SIT). Animal studies show that when allergens are administered topically, they are handled differently, and IgE responses can be reduced.
Frew, Anthony J., Smith, Helen E.
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Anaphylaxis to sublingual immunotherapy
Allergy: European Journal of Allergy and Clinical Immunology, 2006E H, Dunsky +3 more
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Current Opinion in Otolaryngology & Head & Neck Surgery, 2008
Sublingual immunotherapy is an established treatment option for allergic rhinitis in many European countries, but it is not approved in the United States and is considered investigational. Sublingual immunotherapy has received increasing attention in the United States as an alternative to subcutaneous immunotherapy for the treatment of allergic ...
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Sublingual immunotherapy is an established treatment option for allergic rhinitis in many European countries, but it is not approved in the United States and is considered investigational. Sublingual immunotherapy has received increasing attention in the United States as an alternative to subcutaneous immunotherapy for the treatment of allergic ...
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Otolaryngologic Clinics of North America, 2011
Sublingual immunotherapy (SLIT) has been shown to be safe and efficacious in treating allergic rhinitis. It has been used in Europe for more than 20 years, and interest in the United States is increasing. SLIT has been shown to elicit immunologic changes similar to subcutaneous injection immunotherapy.
Sandra Y, Lin, Bryan, Leatherman
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Sublingual immunotherapy (SLIT) has been shown to be safe and efficacious in treating allergic rhinitis. It has been used in Europe for more than 20 years, and interest in the United States is increasing. SLIT has been shown to elicit immunologic changes similar to subcutaneous injection immunotherapy.
Sandra Y, Lin, Bryan, Leatherman
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Sublingual immunotherapy: an update
Current Opinion in Allergy and Clinical Immunology, 2004Sublingual immunotherapy is now officially accepted as a viable alternative to the traditional subcutaneous route, and it is widely used especially in European countries. Despite the large amount of experimental evidence on the safety and efficacy of the method, some concerns still exist, and several aspects need to be clarified: magnitude of the ...
PASSALACQUA, GIOVANNI +2 more
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Sublingual and oral immunotherapy
Immunology and Allergy Clinics of North America, 2004Sublingual immunotherapy (SLIT) is a viable alternative to the subcutaneous route for the treatment of respiratory allergy, whereas the pure oral route has been abandoned because of its lack of efficacy. The main distinctive feature of SLIT is its optimal safety profile, which has been demonstrated in adults and children.
CANONICA, GIORGIO +3 more
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Adherence to Sublingual Immunotherapy
Current Allergy and Asthma Reports, 2016Adherence is a major issue in any medical treatment. Allergen immunotherapy (AIT) is particularly affected by a poor adherence because a flawed application prevents the immunological effects that underlie the clinical outcome of the treatment. Sublingual immunotherapy (SLIT) was introduced in the 1990s, and the early studies suggested that adherence ...
Incorvaia, Cristoforo +3 more
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Current Opinion in Allergy & Clinical Immunology, 2013
It is likely that approval of allergen preparations for sublingual immunotherapy (SLIT) will soon occur in the United States. This article reviews experience with SLIT in this country, concentrating on the large, multicenter trials that will provide the evidence of safety and efficacy necessary to obtain that approval.Large multicenter trials have been
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It is likely that approval of allergen preparations for sublingual immunotherapy (SLIT) will soon occur in the United States. This article reviews experience with SLIT in this country, concentrating on the large, multicenter trials that will provide the evidence of safety and efficacy necessary to obtain that approval.Large multicenter trials have been
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Update on sublingual immunotherapy
Annals of Allergy, Asthma & Immunology, 2006To obtain a current understanding of the mechanisms, clinical indications, efficacy, and safety of sublingual immunotherapy (SLIT) for the treatment of children and adults with allergic rhinitis, asthma, and allergic conjunctivitis.A MEDLINE and Index Medicus search for peer-reviewed articles on SLIT was performed.Since the approval of SLIT by the ...
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Predictors of Completion of Sublingual Immunotherapy
The Laryngoscope, 2020ObjectivesSublingual immunotherapy (SLIT) has emerged as an effective treatment alternative to subcutaneous immunotherapy (SCIT) given its improved safety profile and more convenient dosing. However, SLIT still relies on daily dosing for many years to optimize effectiveness.
Nanki Hura +4 more
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