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Allergen immunotherapy (AIT) is a potentially disease-modifying therapy that is effective for the treatment of allergic rhinitis/conjunctivitis, allergic asthma and stinging insect hypersensitivity.
Boursiquot JN +3 more
europepmc +4 more sources
Diverse Mechanisms of Allergen Specific Immunotherapy
Allergen immunotherapy (AIT) is widely used to establish a tolerant immune response and it is currently the only disease modifying treatment. There are different routes to administer the allergen, including subcutaneous, sublingual, intralymphatic ...
Lacin Cevhertas, Mübeccel Akdis
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Intralymphatic immunotherapy [PDF]
Gold Standard allergen-specific immunotherapy is associated with low efficacy because it requires either many subcutaneous injections of allergen or even more numerous sublingual allergen administrations to achieve amelioration of symptoms ...
Gabriela Senti, Thomas M Kündig
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Preclinical evaluation of alternatives to oral immunotherapy for food allergies
The increasing food allergy incidence has led to significant interest in developing therapies for allergic diseases. Oral allergen-specific immunotherapy (OIT) is a recently FDA-approved therapeutic to treat peanut allergies.
Brandi T. Johnson-Weaver
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Modulation of immune response by nanoparticle-based immunotherapy against food allergens
The increasing prevalence of food allergies worldwide and the subsequent life-threatening anaphylactic reactions often have sparse treatment options, providing only symptomatic relief.
Sivadas Swathi Krishna +7 more
doaj +1 more source
A review of the mechanisms and biomarkers of allergen immunotherapy
Allergen immunotherapy has been shown to be successful in numerous clinical trials, even leading to complete relief of allergic symptoms. However, the molecular mechanisms behind these outcomes remain unclear, substantially hindering introduction of more
Mateusz Wilk +5 more
doaj +1 more source
Allergen-specific immunotherapy (AIT) involves administering allergen extracts. It is used to desensitize allergic patients. Herbal allergen extracts that are optimum in efficacy and fewest in side effects are still challenging to produce.
Soheila Asoudeh Moghanloo +4 more
doaj +1 more source
Background: In the 1990s, the Japanese Society of Allergology (JSA) standardized Japanese cedar pollen allergen vaccines. In the present study, the task force for house dust mite (HDM) allergen standardization of the Committee for Allergens and ...
Toshiro Takai +8 more
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A case of food and aeroallergen sublingual immunotherapy inducing eosinophilic esophagitis
Eosinophilic esophagitis (EoE) has been reported secondary to aeroallergen sublingual immunotherapy (SLIT) and food allergen oral immunotherapy. Gastrointestinal symptoms with food allergen SLIT are uncommon, with no prior reports of cases of food ...
Maureen Bauer, MD +2 more
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ASIT – A SOLUTION IN ALLERGY TREATMENT
This article discusses the place and role of an allergen-specific immunotherapy in the treatment of allergic diseases. It provides an action mechanism, indications for use, contraindications, and side effects of an allergen-specific immunotherapy.
S. V. TSAREV
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