Results 1 to 10 of about 740 (185)

Influence of subretinal drusenoid deposit on retinal sensitivity in age-related macular degeneration [PDF]

Scientific Reports
This retrospective study aimed to assess the impact of subretinal drusenoid deposit (SDD), also known as reticular pseudodrusen, on retinal sensitivity (RS) in patients with intermediate age-related macular degeneration (iAMD) using microperimetry.
Soo Hyun Lim, Taffeta Ching Ning Yamaguchi, Rolf Herrmann, Eun Kyoung Lee, Kun Ho Bae, Un Chul Park, Kyu Hyoung Park, Chang Ki Yoon   +7 more
doaj   +6 more sources

Subretinal drusenoid deposits: An update

Taiwan Journal of Ophthalmology, 2022
A wide spectrum of phenotypic manifestations characterizes age-related macular degeneration (AMD). Drusen is considered the hallmark of AMD and is located underneath the retinal pigment epithelium (RPE). In contrast, subretinal drusenoid deposits (SDDs),
Manuel Monge, Adriana Araya, Lihteh Wu
doaj   +4 more sources

Lysolipids are prominent in subretinal drusenoid deposits, a high-risk phenotype in age-related macular degeneration [PDF]

Frontiers in Ophthalmology, 2023
IntroductionAge related macular degeneration (AMD) causes legal blindness worldwide, with few therapeutic targets in early disease and no treatments for 80% of cases.
David M. G. Anderson, Ankita Kotnala, Ankita Kotnala, Lukasz G. Migas, N. Heath Patterson, Léonore E. M. Tideman, Dongfeng Cao, Bibek Adhikari, Jeffrey D. Messinger, Thomas Ach, Sara Tortorella, Raf Van de Plas, Raf Van de Plas, Christine A. Curcio, Kevin L. Schey   +14 more
doaj   +5 more sources

Photoreceptor perturbation around subretinal drusenoid deposits as revealed by adaptive optics scanning laser ophthalmoscopy [PDF]

American Journal of Ophthalmology, 2014
PURPOSE: To describe the microscopic structure of photoreceptors impacted by subretinal drusenoid deposits, also called pseudodrusen, an extracellular lesion associated with age-related macular degeneration (AMD), using adaptive optics scanning laser ...
Clark, M. E., Curcio, C. A., Girkin, C. A., Owsley, C., Rivero, E. B., Spaide, R. F., Wang, X., Witherspoon, C. D., Zhang, Y.   +8 more
core   +7 more sources

Biometrics, Impact, and Significance of Basal Linear Deposit and Subretinal Drusenoid Deposit in Age-Related Macular Degeneration. [PDF]

Invest Ophthalmol Vis Sci, 2021
Basal linear deposit (BLinD) is a thin layer of soft drusen material. To elucidate the biology of extracellular deposits conferring age-related macular degeneration (AMD) progression risk and inform multimodal clinical imaging based on optical coherence tomography (OCT), we examined lipid content and regional prevalence of BLinD, soft drusen, pre-BLinD,
Chen L, Messinger JD, Kar D, Duncan JL, Curcio CA.   +4 more
europepmc   +6 more sources

Scotopic thresholds on dark-adapted chromatic perimetry in healthy aging and age-related macular degeneration [PDF]

Scientific Reports, 2021
To evaluate the effect of aging, intra- and intersession repeatability and regional scotopic sensitivities in healthy and age-related macular degeneration (AMD) eyes. Intra- and intersession agreement and effect of age was measured in healthy individuals.
Manjot Kaur Grewal, Shruti Chandra, Alan Bird, Glen Jeffery, Sobha Sivaprasad   +4 more
doaj   +2 more sources

Chorioretinal thickness and retinal pigment epithelial degeneration of fellow eyes in patients with unilateral neovascular age-related macular degeneration with subretinal drusenoid deposits [PDF]

BMC Ophthalmology, 2022
Background We sought to investigate the chorioretinal thickness and retinal pigment epithelial (RPE) degenerative features of eyes with early age-related macular degeneration (AMD) and subretinal drusenoid deposits (SDDs) according to the presence of ...
Dongwan Kang, Eun Gyu Yoon, Ki Tae Nam, Cheolmin Yun   +3 more
doaj   +2 more sources

Predictive value of different baseline optical coherence tomography biomarkers for visual acuity changes in neovascular age-related macular degeneration. [PDF]

Int J Retina Vitreous
BACKGROUND: To evaluate baseline optical coherence tomography (OCT) biomarkers in treatment-naïve patients with neovascular age-related macular degeneration (nAMD) and their correlation with visual acuity changes following intravitreal aflibercept ...
Riazi-Esfahani H, Faghihi H, Bazvand F, Mehrabi Bahar M, Khojasteh H, Husein Ahmed A, Faghihi S, Fakhraie A, Zamani MH, Ghasemi S, Asadi Khameneh E, Khalili Pour E.   +11 more
europepmc   +3 more sources

CHOROIDAL THICKNESS AND VASCULARITY VARY WITH DISEASE SEVERITY AND SUBRETINAL DRUSENOID DEPOSIT PRESENCE IN NONADVANCED AGE-RELATED MACULAR DEGENERATION. [PDF]

Retina, 2020
Keenan TD, Klein B, Agrón E, Chew EY, Cukras CA, Wong WT.   +5 more
europepmc   +3 more sources

Spotlight on reticular pseudodrusen [PDF]

Clinical Ophthalmology, 2017
Alessandro Rabiolo,1 Riccardo Sacconi,1,2 Maria Vittoria Cicinelli,1 Lea Querques,1,3 Francesco Bandello,1 Giuseppe Querques1 1Department of Ophthalmology, University Vita-Salute, IRCCS San Raffaele, Milan, 2Eye Clinic, Department of Neurological and ...
Rabiolo A, Sacconi R, Cicinelli MV, Querques L, Bandello F, Querques G   +5 more
doaj   +4 more sources