Influence of subretinal drusenoid deposit on retinal sensitivity in age-related macular degeneration [PDF]
Scientific ReportsThis retrospective study aimed to assess the impact of subretinal drusenoid deposit (SDD), also known as reticular pseudodrusen, on retinal sensitivity (RS) in patients with intermediate age-related macular degeneration (iAMD) using microperimetry.
Soo Hyun Lim +7 more
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Subretinal Drusenoid Deposit Formation: Insights From Turing Patterns. [PDF]
Transl Vis Sci Technol, 2022 The purpose of this study was to demonstrate that the organized formation of subretinal drusenoid deposits (SDDs) may be a Turing pattern.A Java-based computational model of an inferred reaction-diffusion system using paired partial differential equations was used to create topographic images.
Young BK, Shen LL, Del Priore LV.
europepmc +5 more sources
Subretinal drusenoid deposits: An update
Taiwan Journal of Ophthalmology, 2022 A wide spectrum of phenotypic manifestations characterizes age-related macular degeneration (AMD). Drusen is considered the hallmark of AMD and is located underneath the retinal pigment epithelium (RPE). In contrast, subretinal drusenoid deposits (SDDs),
Manuel Monge, Adriana Araya, Lihteh Wu
doaj +3 more sources
Biometrics, Impact, and Significance of Basal Linear Deposit and Subretinal Drusenoid Deposit in Age-Related Macular Degeneration. [PDF]
Invest Ophthalmol Vis Sci, 2021 Basal linear deposit (BLinD) is a thin layer of soft drusen material. To elucidate the biology of extracellular deposits conferring age-related macular degeneration (AMD) progression risk and inform multimodal clinical imaging based on optical coherence tomography (OCT), we examined lipid content and regional prevalence of BLinD, soft drusen, pre-BLinD,
Chen L +4 more
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SUBRETINAL DRUSENOID DEPOSIT IN AGE-RELATED MACULAR DEGENERATION: Histologic Insights Into Initiation, Progression to Atrophy, and Imaging. [PDF]
Retina, 2020 Purpose: To clarify the role of subretinal drusenoid deposits (SDD; pseudodrusen) in the progression of age-related macular degeneration through high-resolution histology. Methods: In 33 eyes of 32 donors (early age-related macular degeneration, n = 15; geographic atrophy, n = 9 ...
Chen L +5 more
europepmc +4 more sources
Association between Subretinal Drusenoid Deposits and Age-Related Macular Degeneration in Multimodal Retinal Imaging. [PDF]
J Clin Med, 2023 Multimodal retinal imaging enables the detection of subretinal drusenoid deposits (SDD) with significantly greater accuracy compared to fundus photography. The study aimed to analyze a relationship between the presence of SDD, the clinical picture of AMD, and disease progression in a 3 year follow-up.
Krytkowska E +4 more
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Subretinal Drusenoid Deposits in a Patient With HELLP (Hemolysis, Elevated Liver Enzymes, Low Platelet) Syndrome. [PDF]
CureusSubretinal drusenoid deposits (SDD) are findings that can be observed in age-related macular degeneration as well as in ischemic ocular diseases. These deposits are believed to be of prognostic importance, as they have been shown to be associated with choroidal neovascularization.
Durmaz Engin C, Karti O, Kandemir K.
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Ophthalmology Science, 2023 Purpose: We evaluate the impact of test target location in assessing rod-mediated dark adaptation (RMDA) along the transition from normal aging to intermediate age-related macular degeneration (AMD).
Cynthia Owsley, PhD, MSPH +5 more
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Basic science observations link subretinal drusenoid deposit formation to retinal pigment epithelial hypoxia. [PDF]
Eye (Lond)Digsby K, Zhang Q, Miller JML.
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Frontiers in Ophthalmology, 2023 IntroductionAge related macular degeneration (AMD) causes legal blindness worldwide, with few therapeutic targets in early disease and no treatments for 80% of cases.
David M. G. Anderson +14 more
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