Results 11 to 20 of about 740 (185)

Association between Subretinal Drusenoid Deposits and Age-Related Macular Degeneration in Multimodal Retinal Imaging. [PDF]

open access: goldJ Clin Med, 2023
Multimodal retinal imaging enables the detection of subretinal drusenoid deposits (SDD) with significantly greater accuracy compared to fundus photography. The study aimed to analyze a relationship between the presence of SDD, the clinical picture of AMD, and disease progression in a 3 year follow-up.
Krytkowska E   +4 more
europepmc   +5 more sources

Subretinal Drusenoid Deposit Formation: Insights From Turing Patterns. [PDF]

open access: yesTransl Vis Sci Technol, 2022
The purpose of this study was to demonstrate that the organized formation of subretinal drusenoid deposits (SDDs) may be a Turing pattern.A Java-based computational model of an inferred reaction-diffusion system using paired partial differential equations was used to create topographic images.
Young BK, Shen LL, Del Priore LV.
europepmc   +5 more sources

Subretinal Drusenoid Deposits in a Patient With HELLP (Hemolysis, Elevated Liver Enzymes, Low Platelet) Syndrome. [PDF]

open access: diamondCureus
Subretinal drusenoid deposits (SDD) are findings that can be observed in age-related macular degeneration as well as in ischemic ocular diseases. These deposits are believed to be of prognostic importance, as they have been shown to be associated with choroidal neovascularization.
Durmaz Engin C, Karti O, Kandemir K.
europepmc   +5 more sources

Clinical and Multimodal Imaging Features of Subretinal Drusenoid Deposits

open access: goldJournal of Ophthalmic and Vision Research, 2021
Purpose: To describe the multimodal imaging (MMI) features of subretinal drusenoid deposits (SDD) in Indian population. Methods: Patients diagnosed to have SDD from January 2016 to December 2018 at our tertiary care center were recruited. The diagnosis of SDD was made on the basis of MMI consisting of a combination of color fundus photography (CFP ...
Devesh Kumawat   +2 more
openalex   +5 more sources

Association of subretinal drusenoid deposits and cardiovascular disease [PDF]

open access: goldScientific Reports
The presence of subretinal drusenoid deposits (SDDs) in patients with age-related macular degeneration (AMD) appears to be correlated with cardiovascular disease (CVD) and may serve as a useful tool for predicting certain forms of CVD. Here, we tested this hypothesis by examining whether patients with AMD with SDDs are more likely to have a ...
Natan Lishinsky-Fischer   +5 more
openalex   +4 more sources

Aberrant lipid accumulation and retinal pigment epithelium dysfunction in PRCD-deficient mice. [PDF]

open access: yesExp Eye Res
Progressive Rod-Cone Degeneration (PRCD) is a peripheral membrane protein predominantly expressed in photoreceptor outer segment (OS) disc membranes with an unknown function. Several mutations in Prcd are implicated in Retinitis pigmentosa (RP) in humans.
Motipally SI   +3 more
europepmc   +3 more sources

LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD<sup>+</sup> depletion. [PDF]

open access: yesCell Rep
Although dysregulated cholesterol metabolism predisposes aging tissues to inflammation and a plethora of diseases, the underlying molecular mechanism remains poorly defined. Here, we show that metabolic and genotoxic stresses, convergently acting through
Terao R   +12 more
europepmc   +3 more sources

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