Results 111 to 120 of about 1,714 (199)

Spotlight on reticular pseudodrusen [PDF]

, 2017
Age-related macular degeneration (AMD) is a leading cause of vision loss in patients >50 years old. The hallmark of the disease is represented by the accumulation of extracellular material between retinal pigment epithelium and the inner collagenous ...
Bandello, Francesco, Cicinelli, Maria Vittoria, Querques, Giuseppe, Querques, Lea, Rabiolo, Alessandro, Sacconi, Riccardo   +5 more
core   +2 more sources

Subretinal Drusenoid Deposits and the Loss of Rod Function in Intermediate Age-Related Macular Degeneration

Investigative Opthalmology & Visual Science, 2018
To compare static rod function obtained with and without photobleach in control and intermediate age-related macular degeneration (iAMD) participants with and without subretinal drusenoid deposits (SDD).In this cross-sectional study, retinal sensitivities within the central 24° retina were obtained twice using a dark-adapted chromatic perimeter, both ...
Rose, Tan, Robyn H, Guymer, Chi D, Luu
openaire   +2 more sources

Adaptive Optics-Transscleral Flood Illumination Imaging of Retinal Pigment Epithelium in Dry Age-Related Macular Degeneration

Cells
Adaptive optics-transscleral flood illumination (AO-TFI) is a novel imaging technique with potential for detecting retinal pigment epithelium (RPE) changes in dry age-related macular degeneration (AMD).
Laura Kowalczuk, Rémy Dornier, Aurélie Navarro, Fanny Jeunet, Christophe Moser, Francine Behar-Cohen, Irmela Mantel   +6 more
doaj   +1 more source

Aberrant Lipid Accumulation and Retinal Pigment Epithelium Dysfunction in Prcd-deficient mice [PDF]

Progressive Rod-Cone Degeneration (PRCD) is a peripheral membrane protein predominantly expressed in photoreceptor outer segment (OS) disc membranes with an unknown function. Several mutations in Prcd are implicated in Retinitis pigmentosa (RP) in humans.
Motipally, Sree Indrani
core   +2 more sources

Topographic and quantitative correlation of structure and function using deep learning in subclinical biomarkers of intermediate age-related macular degeneration

Scientific Reports
To examine the morphological impact of deep learning (DL)-quantified biomarkers on point-wise sensitivity (PWS) using microperimetry (MP) and optical coherence tomography (OCT) in intermediate AMD (iAMD).
Klaudia Birner, Gregor S. Reiter, Irene Steiner, Gábor Deák, Hamza Mohamed, Simon Schürer-Waldheim, Markus Gumpinger, Hrvoje Bogunović, Ursula Schmidt-Erfurth   +8 more
doaj   +1 more source

ReticularNet: Automated Pixel-Level Segmentation of Reticular Pseudodrusen on Near-Infrared Reflectance Images by Deep Learning

Ophthalmology Science
Objective: Reticular pseudodrusen (RPD) represent an important biomarker in age-related macular degeneration (AMD) but are difficult to grade and often assessed only for presence or absence, without quantitative or spatial analysis of RPD burden.
Souvick Mukherjee, PhD, Dylan Wu, Leon von der Emde, MD, Emily Vance, MPH, Marco Ji, MD, Mehdi Emamverdi, MD, Tharindu De Silva, PhD, Alisa T. Thavikulwat, MD, Jayashree Kalpathy-Cramer, PhD, Amitha Domalpally, MD, PhD, Catherine A. Cukras, MD, PhD, Tiarnán D.L. Keenan, BM BCh, PhD   +11 more
doaj   +1 more source

Subretinal Drusenoid Deposits Associated With Complement-Mediated IgA Nephropathy [PDF]

JAMA Ophthalmology, 2014
David R, Lally, Caroline, Baumal
openaire   +2 more sources

In Vivo Correlation Between Macular Pigment Optical Volume and Retinal Layers Thickness [PDF]

Purpose. This study aims to investigate the potential in vivo relationship between macular pigment (MP) and retinal layers thickness in healthy subjects and dry, non-advanced age-related macular degeneration (AMD). Methods.
Airaldi, Matteo, Bertoni, Alice, Casaluci, Marco, Cozzi, Mariano, Green-Gomez, Marina, Invernizzi, Alessandro, Nolan, John M, Romano, Francesco, Ruggi, Giada, Staurenghi, Giovanni   +9 more
core   +1 more source

Fluorescence Lifetime and Spectral Characteristics of Subretinal Drusenoid Deposits and Their Predictive Value for Progression of Age-Related Macular Degeneration. [PDF]

Invest Ophthalmol Vis Sci, 2022
Weber S, Simon R, Schwanengel LS, Curcio CA, Augsten R, Meller D, Hammer M.   +6 more
europepmc   +1 more source

An evidence-based approach to the routine use of optical coherence tomography

, 2019
Optical coherence tomography is an imaging technology that has revolutionised the detection, assessment and management of ocular disease. It is now a mainstream technology in clinical practice and is performed by non-specialised personnel in some ...
Kalloniatis, M , Katalinic, P, Ly, A , Phu, J   +3 more
core   +1 more source