Results 121 to 130 of about 1,714 (199)

Genetic Risk and OCT-Based Phenotypic Associations in Age-Related Macular Degeneration

Ophthalmology Science
Purpose: The risk for developing age-related macular degeneration (AMD) is associated with multiple genetic variants. We aim to evaluate the association of AMD genetic risk variants with specific features of the disease detected by OCT.
Shlomit Jaskoll, Yahel Shwartz, MSc, Adi Kramer, MSc, Sarah Elbaz-Hayoun, PhD, Batya Rinsky, PhD, Michelle Grunin, PhD, Liran Tiosano, MD, Jaime Levy, MD, Brice Nguedia Vofo, MD, MBA, Itay Chowers, MD   +9 more
doaj   +1 more source

Subretinal drusenoid deposits as a biomarker of age-related macular degeneration progression via reduction of the choroidal vascularity index. [PDF]

Eye (Lond), 2023
Abdolrahimzadeh S, Di Pippo M, Sordi E, Cusato M, Lotery AJ.   +4 more
europepmc   +1 more source

Patients with Age-related Macular Degeneration Have Increased Susceptibility to Valvular Heart Disease

Ophthalmology Science
Purpose: Valvular heart disease (VHD) contributes significantly to cardiovascular-related morbidity worldwide. Aortic valve stenosis is the third most common cardiovascular disease in the Western world, after hypertension and coronary artery disease ...
Natan Lishinsky-Fischer, Itay Chowers, MD, PhD, Yahel Shwartz, MSc, Jaime Levy, MD   +3 more
doaj   +1 more source

Associations between Progression of Retinal Pigment Epithelial and Outer Retinal Atrophy and Choroidal Thickness: A 2-Year observation

Ophthalmology Science
Purpose: To evaluate the clinical course of retinal pigment epithelial and outer retinal atrophy (RORA) with best-corrected visual acuity (BCVA) and risk factors for rapid progression to explore the pathogenesis. Design: Retrospective observational study.
Norihiro Nagai, MD, PhD, Hajime Shinoda, MD, PhD, Hisashi Matsubara, MD, PhD, Hiroto Terasaki, MD, PhD, Takao Hirano, MD, PhD, Aki Kato, MD, PhD, Akiko Miki, MD, PhD, Hiromasa Hirai, MD, PhD, Fumiko Murao, MD, PhD, Hiroko Imaizumi, MD, PhD, Fumi Gomi, MD, PhD, Yoshinori Mitamura, MD, PhD, Nahoko Ogata, MD, PhD, Sentaro Kusuhara, MD, PhD, Tsutomu Yasukawa, MD, PhD, Toshinori Murata, MD, PhD, Taiji Sakamoto, MD, PhD, Mineo Kondo, MD, PhD, Yoko Ozawa, MD, PhD   +18 more
doaj   +1 more source

Spatially Resolved Association of Structural Biomarkers on Retinal Function in Non-Exudative Age-Related Macular Degeneration Over 4 Years [PDF]

PURPOSE. To longitudinally assess the impact of high-risk structural biomarkers for natural disease progression in non-exudative age-related macular degeneration (AMD) on spatially resolved mesopic and scotopic fundus-controlled perimetry testing ...
Ach, Thomas, Döngelci, Senem, Emde, Leon von der, Hasenauer, Jan, Holz, Frank G., Saßmannshausen, Marlene, Schmitz-Valckenberg, Steffen, Sloan, Kenneth R., Vaisband, Marc   +8 more
core   +1 more source

Rheumatic fever and long-term use of benzathine penicillin as possible risk factors for extensive macular atrophy with pseudodrusen in a Brazilian cohort

International Journal of Retina and Vitreous
Background Although there has been a large increase in the number of extensive macular atrophy with pseudodrusen (EMAP) cases, the basic aspects of this disease remain unknown.
Carlos Augusto Moreira-Neto, Rafaella Atherino Schmidt Andujar, John Chii Tyng Chao, Huber Vasconcelos, Fábio Eduardo Eberhardt Alves, Gabriela Doná Rodrigues, Bruno Hirt, Jayme Arana, Eduardo Cunha Souza, André Maia, Juliana Maria Ferraz Sallum, Carlos Augusto Moreira   +11 more
doaj   +1 more source

Functional clinical endpoints and their correlations in eyes with AMD with and without subretinal drusenoid deposits-a pilot study. [PDF]

Eye (Lond), 2022
Grewal MK, Chandra S, Gurudas S, Rasheed R, Sen P, Menon D, Bird A, Jeffery G, Sivaprasad S.   +8 more
europepmc   +1 more source

Phenotypic Heterogeneity and its influence on visual and morphological outcomes in age-related macular degeneration [PDF]

Age related macular degeneration (AMD) is a complex condition with significant heterogeneity in presentation, rate of progression and outcomes. The overarching aim of the studies in this thesis was to characterize the heterogeneity by conducting in-depth
Chandra, Shruti
core  

Intermediate age related macular degeneration - noninvasive multimodal analysis and longitudinal study [PDF]

Age-related Macular Degeneration (AMD) is an important cause of irreversible visual impairment, secondary to degenerative macular disorder. AMD can compromise central vision, essential for reading and for recognizing small details.
Rio Pedro Flores, Rita Maria
core  

Reticular Pseudodrusen Are Subretinal Drusenoid Deposits

Reticular Pseudodrusen Are Subretinal Drusenoid Deposits
Purpose: To characterize reticular pseudodrusen, a potential risk factor for late age-related macular degeneration. Design: Retrospective, observational case series. Participants: Fifty-eight eyes of 33 patients with pseudodrusen (20 female). Methods: Consecutive patients with reticular pseudodrusen, diagnosed by their typical appearance and ...
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