Results 21 to 30 of about 1,714 (199)

Assessing the prevalence of extensive macular atrophy with pseudodrusen-like appearance in patients with rheumatic fever-associated valvular heart disease: a cross-sectional study [PDF]

International Journal of Retina and Vitreous
Background Extensive macular atrophy with pseudodrusen-like appearance (EMAP) is a rare retinal disorder characterized by bilateral macular atrophy and subretinal drusenoid deposits (SDDs), typically occurring earlier and progressing faster than age ...
Antonio S. F. Cassavia Junior, Victor Bellanda, Leticia O. Audi, Gabriel Castilho S. Barbosa, Renata A. M. Caravelas, Gustavo J. Volpe, Henrique T. Moreira, Andre Schmidt, Rodrigo Jorge   +8 more
doaj   +2 more sources

Association between Subretinal Drusenoid Deposits and Age-Related Macular Degeneration in Multimodal Retinal Imaging. [PDF]

J Clin Med, 2023
Multimodal retinal imaging enables the detection of subretinal drusenoid deposits (SDD) with significantly greater accuracy compared to fundus photography. The study aimed to analyze a relationship between the presence of SDD, the clinical picture of AMD, and disease progression in a 3 year follow-up.
Krytkowska E, Olejnik-Wojciechowska J, Grabowicz A, Safranow K, Machalińska A.   +4 more
europepmc   +3 more sources

Internal Carotid Artery Stenosis and Ipsilateral Subretinal Drusenoid Deposits. [PDF]

Invest Ophthalmol Vis Sci
Subretinal drusenoid deposits (SDDs) in age-related macular degeneration (AMD) are strongly associated with vasculopathies such as myocardial infarction and ischemic stroke. This study evaluates ischemic stroke subjects for SDDs to determine whether ocular hypoperfusion from internal carotid artery (ICA) stenosis is associated with ipsilateral SDDs.A ...
Mordechaev E, Jo JJ, Mordechaev S, Govindaiah A, Fei Y, Tai K, Tong Y, Bhuiyan A, Weinberger J, Deobhakta A, Dhamoon M, Rosen RB, Lema GMC, Smith RT.   +13 more
europepmc   +3 more sources

Spatial Dissociation of Subretinal Drusenoid Deposits and Impaired Scotopic and Mesopic Sensitivity in AMD. [PDF]

Invest Ophthalmol Vis Sci, 2022
Subretinal drusenoid deposits (SDD) first appear in the rod-rich perifovea and can extend to the cone-rich fovea. To refine the spatial relationship of visual dysfunction with SDD burden, we determined the topography of mesopic and scotopic light sensitivity in participants with non-neovascular AMD with and without SDD.Thirty-three subjects were ...
Zhang Y, Sadda SR, Sarraf D, Swain TA, Clark ME, Sloan KR, Warriner WE, Owsley C, Curcio CA.   +8 more
europepmc   +3 more sources

Prevalence and determinants of subretinal drusenoid deposits in patients' first-degree relatives. [PDF]

Graefes Arch Clin Exp Ophthalmol, 2023
Abstract Purpose Subretinal drusenoid deposits (SDDs) are distinct extracellular alteration anterior to the retinal pigment epithelium (RPE). Given their commonly uniform phenotype, a hereditary predisposition seems likely. Hence, we aim to investigate prevalence and determinants in patients’ first-degree relatives.
Mauschitz MM, Hochbein BJ, Klinkhammer H, Saßmannshausen M, Terheyden JH, Krawitz P, Finger RP.   +6 more
europepmc   +4 more sources

Subretinal Drusenoid Deposit Formation: Insights From Turing Patterns

Translational Vision Science & Technology, 2022
The purpose of this study was to demonstrate that the organized formation of subretinal drusenoid deposits (SDDs) may be a Turing pattern.A Java-based computational model of an inferred reaction-diffusion system using paired partial differential equations was used to create topographic images.
Young, Benjamin K, Shen, Liangbo L, Del Priore, Lucian V   +2 more
openaire   +4 more sources

Progressive Photoreceptor Dysfunction and Age-Related Macular Degeneration-Like Features in rp1l1 Mutant Zebrafish

Cells, 2020
Photoreceptor disease results in irreparable vision loss and blindness, which has a dramatic impact on quality of life. Pathogenic mutations in RP1L1 lead to photoreceptor degenerations such as occult macular dystrophy and retinitis pigmentosa.
Nicole C. L. Noel, Nathan J. Nadolski, Jennifer C. Hocking, Ian M. MacDonald, W. Ted Allison   +4 more
doaj   +1 more source

Age-related macular degeneration eyes presenting with cuticular drusen and reticular pseudodrusen

Scientific Reports, 2022
This study aimed to describe the clinical characteristics of age-related macular degeneration (AMD) eyes with both cuticular drusen (CD) and reticular pseudodrusen (RPD).
Je Moon Yoon, Dong Hoon Shin, Mingui Kong, Don-Il Ham   +3 more
doaj   +1 more source

Biologically Guided Optimization of Test Target Location for Rod-mediated Dark Adaptation in Age-related Macular Degeneration

Ophthalmology Science, 2023
Purpose: We evaluate the impact of test target location in assessing rod-mediated dark adaptation (RMDA) along the transition from normal aging to intermediate age-related macular degeneration (AMD).
Cynthia Owsley, PhD, MSPH, Thomas A. Swain, MPH, Gerald McGwin, Jr., PhD, MS, Mark E. Clark, MEng, Deepayan Kar, MS, Christine A. Curcio, PhD   +5 more
doaj   +1 more source

Progressive chorioretinal involvement in a patient with light-chain (AL) amyloidosis: a case report

BMC Ophthalmology, 2020
Background To report an unusual case of light-chain (AL) amyloidosis with progressive bilateral chorioretinal abnormalities documented with short-wavelength autofluorescence, SD-OCT, fluorescein and indocyanine green angiography.
Edouard Augstburger, José-Alain Sahel, Isabelle Audo   +2 more
doaj   +1 more source