Results 41 to 50 of about 1,783 (192)

DYNAMISM OF DOT SUBRETINAL DRUSENOID DEPOSITS IN AGE-RELATED MACULAR DEGENERATION DEMONSTRATED WITH ADAPTIVE OPTICS IMAGING. [PDF]

open access: greenRetina, 2018
Zhang Y   +8 more
europepmc   +3 more sources

Subretinal Drusenoid Deposit Formation: Insights From Turing Patterns

open access: yesTranslational Vision Science & Technology, 2022
The purpose of this study was to demonstrate that the organized formation of subretinal drusenoid deposits (SDDs) may be a Turing pattern.A Java-based computational model of an inferred reaction-diffusion system using paired partial differential equations was used to create topographic images.
Young, Benjamin K   +2 more
openaire   +4 more sources

Progressive Photoreceptor Dysfunction and Age-Related Macular Degeneration-Like Features in rp1l1 Mutant Zebrafish

open access: yesCells, 2020
Photoreceptor disease results in irreparable vision loss and blindness, which has a dramatic impact on quality of life. Pathogenic mutations in RP1L1 lead to photoreceptor degenerations such as occult macular dystrophy and retinitis pigmentosa.
Nicole C. L. Noel   +4 more
doaj   +1 more source

Age-related macular degeneration eyes presenting with cuticular drusen and reticular pseudodrusen

open access: yesScientific Reports, 2022
This study aimed to describe the clinical characteristics of age-related macular degeneration (AMD) eyes with both cuticular drusen (CD) and reticular pseudodrusen (RPD).
Je Moon Yoon   +3 more
doaj   +1 more source

Biologically Guided Optimization of Test Target Location for Rod-mediated Dark Adaptation in Age-related Macular Degeneration

open access: yesOphthalmology Science, 2023
Purpose: We evaluate the impact of test target location in assessing rod-mediated dark adaptation (RMDA) along the transition from normal aging to intermediate age-related macular degeneration (AMD).
Cynthia Owsley, PhD, MSPH   +5 more
doaj   +1 more source

Progressive chorioretinal involvement in a patient with light-chain (AL) amyloidosis: a case report

open access: yesBMC Ophthalmology, 2020
Background To report an unusual case of light-chain (AL) amyloidosis with progressive bilateral chorioretinal abnormalities documented with short-wavelength autofluorescence, SD-OCT, fluorescein and indocyanine green angiography.
Edouard Augstburger   +2 more
doaj   +1 more source

Epidemiology of geographic atrophy and its precursor features of intermediate age‐related macular degeneration

open access: yesActa Ophthalmologica, Volume 101, Issue 8, Page 839-856, December 2023., 2023
Abstract Globally age‐related macular degeneration (AMD) is a leading cause of blindness with a significant impact on quality of life. Geographic atrophy (GA) is the atrophic late form of AMD and its prevalence increases markedly with age with around 1 in 5 persons aged 85 and above having GA in at least one eye.
Stela Vujosevic   +2 more
wiley   +1 more source

Drusenoid pigment epithelial detachments and age-related macular degeneration [PDF]

open access: yes, 2020
Patients with age-related macular degeneration (AMD) and serous or drusenoid pigment epithelial detachments (PEDs) have a high risk of progression to geographic atrophy, choroidal neovascularization, and a loss of visual function. The abundance of lipids
Tvenning, Arnt-Ole
core   +1 more source

Multimodal imaging and deep learning in geographic atrophy secondary to age‐related macular degeneration

open access: yesActa Ophthalmologica, Volume 101, Issue 8, Page 881-890, December 2023., 2023
Abstract Geographic atrophy (GA) secondary to age‐related macular degeneration is among the most common causes of irreversible vision loss in industrialized countries. Recently, two therapies have been approved by the US FDA. However, given the nature of their treatment effect, which primarily involves a relative decrease in disease progression ...
Maximilian Pfau   +5 more
wiley   +1 more source

Reticular Pseudodrusen and Its Importance in AMD

open access: yesDelhi Journal of Ophthalmology, 2020
This article aims to provide an insight into the pathophysiology and clinical features of the emerging entity called reticular pseudodrusen (RPD). The diagnosis of RPD requires multimodal imaging and it is important to distinguish them from other types ...
Prachi Abhishek Dave   +4 more
doaj   +1 more source

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