Results 81 to 90 of about 1,783 (192)

SUBRETINAL DRUSENOID DEPOSIT IN AGE-RELATED MACULAR DEGENERATION

Retina, 2020
Purpose: To clarify the role of subretinal drusenoid deposits (SDD; pseudodrusen) in the progression of age-related macular degeneration through high-resolution histology. Methods: In 33 eyes of 32 donors (early age-related macular degeneration, n = 15; geographic atrophy, n = 9 ...
Ling, Chen, Jeffrey D, Messinger, Yuhua, Zhang, Richard F, Spaide, K Bailey, Freund, Christine A, Curcio   +5 more
openaire   +3 more sources

Retinal Pigment Epithelium Degeneration Associated With Subretinal Drusenoid Deposits in Age-Related Macular Degeneration. [PDF]

Am J Ophthalmol, 2017
To test whether increased light transmission (hypertransmission) through subretinal drusenoid deposits (SDD) into the choroid in age-related macular degeneration (AMD) represented retinal pigment epithelium (RPE) degeneration.Cross-sectional study.Nineteen eyes of 12 patients with early- to intermediate-stage AMD and 18 eyes of 12 normal subjects were ...
Xu X, Liu X, Wang X, Clark ME, McGwin G, Owsley C, Curcio CA, Zhang Y.   +7 more
europepmc   +4 more sources

Macular Atrophy of the Retinal Pigment Epithelium in Patients with Neovascular Age-Related Macular Degeneration: What is the Link? Part I: A Review of Disease Characterization and Morphological Associations

Ophthalmology and Therapy, 2019
Introduction The purpose of this review was to explore the potential link between macular atrophy (MA) of the retinal pigment epithelium in patients with neovascular age-related macular degeneration (nAMD) with the disease characteristics and ...
Mania Horani, Sajjad Mahmood, Tariq M. Aslam   +2 more
doaj   +1 more source

Drusen characteristics of type 2 macular neovascularization in age-related macular degeneration

BMC Ophthalmology, 2020
Background Type 2 macular neovascularization (MNV) is supposed to be a rare condition in age-related macular degeneration (AMD). The main purpose of this study was to assess accompanying factors of type 2 MNV in AMD.
Daniel Ahmed, Martin Stattin, Anna-Maria Haas, Alexandra Graf, Katharina Krepler, Siamak Ansari-Shahrezaei   +5 more
doaj   +1 more source

Posterior Microphthalmia, Peripheral Pigmentary Retinal Changes, Yellow Lesions, and Cleft Lip: A Case Report and Literature Review

Case Reports in Ophthalmological Medicine, 2019
Purpose. Posterior microphthalmia is a sporadic or inherited developmental ocular anomaly that may occur isolated or in association with multiple ocular and systemic anomalies.
Nasser G. Alsaedi, Khalid Alrubaie
doaj   +1 more source

Risk factors associated with reticular pseudodrusen versus large soft drusen [PDF]

, 2014
PURPOSE: To investigate genetic, environmental, and systemic risk factors in prospectively identified subjects with the age-related macular degeneration (AMD) phenotypes of (1) reticular pseudodrusen without large soft drusen and (2) large soft drusen ...
Boddu, S., Freund, K. B., Lee, M. D., Marmor, M., Marsiglia, M., Smith, R. T.   +5 more
core   +3 more sources

Deep Learning‐Based Detection of Reticular Pseudodrusen in Age‐Related Macular Degeneration

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Reticular pseudodrusen (RPD) signify a critical phenotype driving vision loss in age‐related macular degeneration (AMD). This study sought to develop and externally test a deep learning (DL) model to detect RPD on optical coherence tomography (OCT) scans with expert‐level performance.
Himeesh Kumar, Yelena Bagdasarova, Scott Song, Doron G. Hickey, Amy C. Cohn, Mali Okada, Robert P. Finger, Jan H. Terheyden, Ruth E. Hogg, Pierre‐Henry Gabrielle, Louis Arnould, Maxime Jannaud, Xavier Hadoux, Peter van Wijngaarden, Carla J. Abbott, Lauren A. B. Hodgson, Roy Schwartz, Adnan Tufail, Emily Y. Chew, Cecilia S. Lee, Erica L. Fletcher, Melanie Bahlo, Brendan R. E. Ansell, Alice Pébay, Robyn H. Guymer, Aaron Y. Lee, Zhichao Wu   +26 more
wiley   +1 more source

Ten‐Year Incidence, Risk Factors and Progression Rate of Macular Atrophy in Neovascular Age‐Related Macular Degeneration

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the 10‐year cumulative incidence, progression rates, and risk factors for macular atrophy (MA) in neovascular age‐related macular degeneration (nAMD) patients receiving long‐term anti‐vascular endothelial growth factor (VEGF) therapy.
Francesco Romano, Marco Casaluci, Antonio Valastro, Matteo Airaldi, Paolo Milella, Francesco Pozzo Giuffrida, Elisa Cozzi, Andrea Aretti, Kelvin YC Teo, Chui Ming Gemmy Cheung, Marco Nassisi, Francesco Viola, Giovanni Staurenghi, Alessandro Invernizzi   +13 more
wiley   +1 more source

Visual Function Assessment in Geographic Atrophy: A Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Geographic atrophy (GA) causes significant vision impairment and reduction in vision‐related quality of life. Fundus autofluorescence (FAF) is the gold standard of structural assessment of GA but is a surrogate marker for vision loss, which can be assessed by tests of visual function and functional vision.
Ye Li, Lauren N. Ayton, Adrian T. Fung
wiley   +1 more source

Scanning laser ophthalmoscopy retroillumination: applications and illusions

International Journal of Retina and Vitreous, 2022
Scanning laser ophthalmoscopes (SLOs) are used widely for reflectance, fluorescence or autofluorescence photography and less commonly for retroillumination imaging.
Martin A. Mainster, Thomas Desmettre, Giuseppe Querques, Patricia L. Turner, Gerardo Ledesma-Gil   +4 more
doaj   +1 more source