Results 81 to 90 of about 1,714 (199)

Is Reticular Macular Disease a Choriocapillaris Perfusion Problem? [PDF]

, 2012
The etiology of reticular macular disease (RMD), a sub-phenotype of age-related macular degeneration (AMD), is controversial and has not been clarified.
A. Martillo, Miguel, Bearelly, Srilaxmi, D. Lee, Michele, Marsiglia, Marcela, Pumariega, Nicole, Smith, Theodore   +5 more
core   +5 more sources

Automated detection and classification of early AMD biomarkers using deep learning [PDF]

, 2019
Age-related macular degeneration (AMD) affects millions of people and is a leading cause of blindness throughout the world. Ideally, affected individuals would be identified at an early stage before late sequelae such as outer retinal atrophy or ...
Hu Z. J., kanagasingam Y., Lindenberg S., Nassisi M., Sadda S., Saha S., Wang M.   +6 more
core   +1 more source

Hyperautofluorescent material inside areas of macular atrophy may reveal non‐lipofuscin fluorophores in late stage AMD

Acta Ophthalmologica, Volume 103, Issue 1, Page e66-e75, February 2025.
Abstract Purpose To characterize fundus autofluorescence (FAF) in complete (cRORA) and incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) by fluorescence lifetime imaging ophthalmology (FLIO). Methods Overall, 98 macular atrophy (MA) lesions in 42 eyes of 37 age‐related macular degeneration (AMD) patients (mean age: 80.9 ± 5.8 ...
Melih Tarhan, Daniel Meller, Martin Hammer   +2 more
wiley   +1 more source

Chronic Central Serous Chorioretinopathy in Elderly Subjects: Structure and Blood Flow Characteristics of Retina and Choroid

Ophthalmology and Therapy, 2023
Introduction With advancements in imaging technology, researchers have been able to identify more distinctive imaging features of central serous chorioretinopathy (CSC).
Pei Liu, Haixin Fang, Guangqi An, Bo Jin, Chenyu Lu, Shu Li, Fan Yang, Liping Du, Xuemin Jin   +8 more
doaj   +1 more source

Extracting full information from OCT scans—signs of early age‐related macular degeneration within inner retinal layers by local neighbourhood statistics. Part I: Methodology

Ophthalmic and Physiological Optics, Volume 45, Issue 1, Page 231-246, January 2025.
Abstract Background and Objectives Associations between the occurrence of early age‐related macular degeneration (AMD) and alterations in retinal layer thicknesses have been reported based on classical processing of optical coherence tomography (OCT) data by noise removal and subsequent image segmentation.
Marcus Wagner, Julia Sommerer, Franziska G. Rauscher   +2 more
wiley   +1 more source

Extracting full information from OCT scans—signs of early age‐related macular degeneration within inner retinal layers by local neighbourhood statistics. Part II: Results

Ophthalmic and Physiological Optics, Volume 45, Issue 1, Page 247-268, January 2025.
Abstract Background and Objectives Associations between the occurrence of early age related macular degeneration (AMD) and alterations in retinal layer thicknesses have been reported, based on classical processing of optical coherence tomography (OCT) data by noise removal and subsequent image segmentation. However, speckle noise within OCT data itself
Marcus Wagner, Julia Sommerer, Franziska G. Rauscher   +2 more
wiley   +1 more source

Pachychoroid neovasculopathy and age-related macular degeneration. [PDF]

, 2015
Pachychoroid neovasculopathy is a recently proposed clinical entity of choroidal neovascularization (CNV). As it often masquerades as neovascular age-related macular degeneration (AMD), it is currently controversial whether pachychoroid neovasculopathy ...
Akagi-Kurashige, Yumiko, Miyake, Masahiro, Nakanishi, Hideo, Oishi, Akio, Ooto, Sotaro, Takahashi, Ayako, Tamura, Hiroshi, Tsujikawa, Akitaka, Ueda-Arakawa, Naoko, Yamashiro, Kenji, Yoshikawa, Munemitsu, Yoshimura, Nagahisa   +11 more
core   +1 more source

Mimickers of hydroxychloroquine retinal toxicity

Clinical &Experimental Ophthalmology, Volume 52, Issue 9, Page 1003-1015, December 2024.
Abstract Hydroxychloroquine (HCQ) retinal toxicity is an important entity that can be challenging to differentiate from its mimickers. Bull's eye maculopathy is the classical presentation of HCQ retinopathy; however, its differential includes several drug‐related retinal toxicities, inherited retinal disorders, and systemic conditions with associated ...
Peter Jones, Gagan Kalra, Mayss Al‐Sheikh, Jay Chhablani   +3 more
wiley   +1 more source

Subretinal drusenoid deposits, age-related macular degeneration, and cardiovascular disease

Asia-Pacific Journal of Ophthalmology
Decades of studies on age-related macular degeneration (AMD), cardiovascular disease and stroke have not found consistent associations between AMD and systemic vascular disease. This study suggests that there is in fact no general relationship, but instead a strong, specific association between only the subretinal drusenoid deposit (SDD) phenotype of ...
R Theodore, Smith, Timothy W, Olsen, Victor, Chong, Judy, Kim, Martin, Hammer, Gareth, Lema, Avnish, Deobhakta, Anna, Tan, Yuehong, Tong, Katy, Tai, Yang, Fei, Emanuel, Mordechaev, Gerardo, Ledesma-Gil, Oscar, Otero-Marquez, Richard B, Rosen, Alauddin, Bhuiyan, Sobha, Sivaprasad, Philip J, Rosenfeld   +17 more
openaire   +2 more sources

Autophagy in drusen biogenesis secondary to age‐related macular degeneration

Acta Ophthalmologica, Volume 102, Issue 7, Page 759-772, November 2024.
Abstract Age‐related macular degeneration (AMD) is an emerging cause of blindness in aged people worldwide. One of the key signs of AMD is the degeneration of the retinal pigment epithelium (RPE), which is indispensable for the maintenance of the adjacent photoreceptors.
Juha M. T. Hyttinen, Ali Koskela, Janusz Blasiak, Kai Kaarniranta   +3 more
wiley   +1 more source