Results 81 to 90 of about 150,966 (300)
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Settlement characteristics of major infrastructures in Shanghai [PDF]
Proceedings of the International Association of Hydrological Sciences, 2015 Critical infrastructures in Shanghai have undergone uneven settlement since their operation, which plays an important role in affecting the security of Shanghai.
X. Jiao +5 more
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
The origin of fault scarps & fissures on moorland plateaux & in the vicinity of landslides, in the South Wales Coalfield, UK [PDF]
, 2010 Fault scarps and fissures occur on moorland plateaux and in the vicinity of deep-seated landslides in the South Wales Coalfield, UK. These scarps may reach about 4 m in height and 3-4 km in length.
Donnelly, L.J. +2 more
core
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Interim Report on Studies of the Mw ~7.9 Earthquake of 3 May 2006, Kingdom of Tonga [PDF]
, 2018 The very large and rare Mw ~7.9 Earthquake of 3 May 2006 in the Kingdom of Tonga aroused great interest among both Tongan scientists and their colleagues in Australia, New Zealand, and the United States.
Beavan, John +15 more
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Remote Sensing, 2020 The long-term overexploitation of groundwater leads to serious land subsidence and threatens the safety of Beijing-Tianjin-Hebei (BTH). In this paper, an interferometric point target analysis (IPTA) with small baseline subset InSAR (SBAS-InSAR) technique
Chaofan Zhou +8 more
doaj +1 more source
Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa +10 more
wiley +1 more source
The worsening impacts of land reclamation assessed with Sentinel-1: The Rize (Turkey) test case [PDF]
, 2019 Massive amounts of land are being reclaimed to build airports, new cities, ports, and highways. Hundreds of kilometers are added each year, as coastlines are extended further out to the sea.
Althuwaynee +50 more
core +1 more source