FEBS Open Bio, EarlyView.Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal +2 more
wiley +1 more source
Top-Accessed Article: UV Light Tanning as a Type of Substance-Related Disorder [PDF]
, 2012 Elizabeth K. Farhat
openalex +1 more source
Affect Dysregulation As A Mediator Of The Relationship Between Childhood Trauma And Comorbid Substance Use Disorder And Bulimia Nervosa [PDF]
, 2014 Eating disorders are serious, potentially life-threatening psychiatric disorders associated with a variety of negative medical, social, and psychological consequences.
Crawford, Brianna Joelle
core +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
The Economic Burden of Pharmaceuticals in People Diagnosed with Depression, Anxiety-Related Disorder and Substance use in Australia [PDF]
, 2015 Y Lee +3 more
openalex +1 more source
Event-related functional magnetic resonance imaging of reward-related brain circuitry in children and adolescents [PDF]
, 2007 BACKGROUND: Functional disturbances in reward-related brain systems are thought to play a role in the development of mood, impulse, and substance abuse disorders. Studies in non-human primates have identified brain regions, including the dorsal / ventral
May, John Christopher
core
Aging and Cancer, EarlyView.Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
Measuring Substance-Related Disorders Using Canadian Administrative Health Databanks: Interprovincial Comparisons of Recorded Diagnostic Rates, Incidence Proportions and Mortality Rate Ratios. [PDF]
Can J Psychiatry, 2022 Huỳnh C +12 more
europepmc +1 more source
Substance-related and addictive disorders among adults with intellectual and developmental disabilities (IDD): an Ontario population cohort study [PDF]
, 2016 Elizabeth Lin +6 more
openalex +1 more source
Effects of Substance Use, Recovery, and Non–Drug-Related Online Community Participation on the Risk of a Use Episode During Remission From Opioid Use Disorder: Longitudinal Observational Study [PDF]
, 2022 Elahe Naserianhanzaei, Miriam Koschate
openalex +1 more source