Results 51 to 60 of about 671,072 (327)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Contractures and Drug Abuse [PDF]
Indian Journal of Physical Medicine & Rehabilitation, 2009 Contracture is limitation of complete range of motion,active or passive, due to joint, muscle or soft-tissuelimitations. Myogenic contractures can be due to trauma,inflammation, degenerative changes, ischemia, andspasticity.
Srikumar V +4 more
doaj
Attacks intended to seriously harm and co-occurring drug use among youth in the United States [PDF]
, 2016 BACKGROUND: While it is known that substance use and violence co-occur, less is understood in terms of how this relationship might vary based on the degree of youth involvement in violence.
Clark Goings, Trenette +4 more
core +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Journal of Education and Health Promotion, 2018 Background: Substance abuse and mental disorder often coexist and may cause several consequences in sociooccupational functioning and health care and management. Indian data are sparse in this area.
Mona Srivastava +2 more
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Lifting the Burden of Addiction: Philanthropic Opportunities to Address Substance Use Disorders in the United States [PDF]
, 2015 Substance use disorders (SUDs), also known as substance abuse or addiction, affect an estimated 20 million or more adolescents and adults in the U.S. This guidance provides philanthropic funders with the tools & information to reduce immediate harm from ...
Cecily Wallman-Stokes +6 more
core
Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. [PDF]
, 2013 Discrete time survival analysis was used to assess the age-specific association of event-related oscillations (EROs) and CHRM2 gene variants on the onset of regular alcohol use and alcohol dependence.
Almasy, Laura +20 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Frequency of Parental Psychopathology in Children with Attention Deficit Hyperactivity Disorder [PDF]
, 2012 Parental mental health concerns place children at a significantly greater risk of lower social, psychological and physical health than children in families not affected by mental illness.
Bhat, SM, Latha, KS, Nair, RB
core +1 more source