Profile of drug users in the residential treatment centers of Tehran, Iran [PDF]
Background: The current study aimed at determining the pattern of drug dependence and its related factors in mid-term residential treatment centers (MTRCs). Methods: The current cross-sectional study was conducted on all drug dependent people residing in
Hossein Akbari+5 more
doaj +1 more source
Neural mechanisms of affective instability and cognitive control in substance use
Objective: We explored the impact of affect on cognitive control as this relates to individual differences in affective instability and substance use.
Bodkyn, Carmen N., Holroyd, Clay
core +1 more source
Association of Mental Disorders in Early Adulthood and Later Psychiatric Hospital Admissions and Mortality in a Cohort Study of More Than 1 Million Men [PDF]
Context Mental disorders have been associated with increased mortality, but the evidence is primarily based on hospital admissions for psychoses. The underlying mechanisms are unclear.
Batty, G David+5 more
core +1 more source
Cognitive behavioral therapy for adults with substance abuse disorders: A meta-analysis of randomized controlled trials since 2007 [PDF]
A meta-analysis was conducted assessing the effectiveness of cognitive behavioral therapy (CBT) to treat persons with substance abuse disorders (SUD) to update a previous study by Magill and Ray (2009).
Bayles, Cody J.
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
The classification of substance and behavioural addictions: A preliminary investigation [PDF]
The term addiction has been used to refer to impaired control over substance use for several centuries however recently there has been a shift toward using this term in the context of non-substance use disorders, such as pathological gambling.
McLaughlan, Andre David+1 more
core +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Background: Substance abuse and mental disorder often coexist and may cause several consequences in sociooccupational functioning and health care and management. Indian data are sparse in this area.
Mona Srivastava+2 more
doaj +1 more source
The variance shared across forms of childhood trauma is strongly associated with liability for psychiatric and substance use disorders [PDF]
Introduction: Forms of childhood trauma tend to co-occur and are associated with increased risk for psychiatric and substance use disorders. Commonly used binary measures of trauma exposure have substantial limitations.
Agrawal, Arpana+13 more
core +3 more sources