Results 61 to 70 of about 671,072 (327)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Pattern of psychoactive substance use by students - Ribeirão Preto

open access: yesSaúde em Debate
The aim was to analyze the use of psychoactive substances among students in their final year of middle school and high school in Ribeirão Preto and reflect on the pattern of psychoactive drug use based on epidemiological studies conducted over the last ...
Margarita Antonia Villar Luis   +4 more
doaj   +1 more source

A study of high risk behaviour among LGBT people of Manipur

open access: yesOpen Journal of Psychiatry and Allied Sciences, 2018
Aim: Over the last two decades, there has been increasing demand for the awareness on sexual minority people’s lives and issues throughout the world. In the recent years, India is witnessing a change in public attitude and concern in the field of sexual ...
Niranjan Hebbar YR, Rajkumar Lenin Singh
doaj   +1 more source

Differences in temperament and character dimensions in adolescents with various conduct disorders [PDF]

open access: yesVojnosanitetski Pregled, 2016
Background/Aim. Adolescence is characterized both by a large developmental potential and by an increased risk for emergence of different forms of psychopathology. International classifications of mental disorders recognize the psychopathology of
Dukanac Vesna   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Vocational Rehabilitation for Individuals With Substance-Related Disorders

open access: yesIranian Rehabilitation Journal, 2019
Objectives: The present review study aimed at investigating the vocational rehabilitation of individuals with drug dependence disorders.  Methods: Based on the research method, a comprehensive search was conducted in the following databases: PubMed ...
Younes Doostian   +4 more
doaj  

Current Concepts on Drug Abuse and Dependence [PDF]

open access: yes, 2015
Drug addiction is a complex disease characterized by compulsive and uncontrollable desire to seek and consume the drug. In time, drug-related terminology has undergone many changes, arising from the deepening of the mechanisms of action, but also about ...
Baconi, Daniela Luiza   +5 more
core   +3 more sources

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