Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Pattern of psychoactive substance use by students - Ribeirão Preto
The aim was to analyze the use of psychoactive substances among students in their final year of middle school and high school in Ribeirão Preto and reflect on the pattern of psychoactive drug use based on epidemiological studies conducted over the last ...
Margarita Antonia Villar Luis +4 more
doaj +1 more source
A study of high risk behaviour among LGBT people of Manipur
Aim: Over the last two decades, there has been increasing demand for the awareness on sexual minority people’s lives and issues throughout the world. In the recent years, India is witnessing a change in public attitude and concern in the field of sexual ...
Niranjan Hebbar YR, Rajkumar Lenin Singh
doaj +1 more source
Differences in temperament and character dimensions in adolescents with various conduct disorders [PDF]
Background/Aim. Adolescence is characterized both by a large developmental potential and by an increased risk for emergence of different forms of psychopathology. International classifications of mental disorders recognize the psychopathology of
Dukanac Vesna +3 more
doaj +1 more source
Interpersonal and Biological Factors Related to Alcohol and Substance Use Disorders: An Editorial [PDF]
Regina B. Baronia +2 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A systematic literature review reveals that noninvasive neuromodulation (rTMS, tDCS) changes resting-state fMRI in adults with substance-related and addictive disorders [PDF]
Amy E. Bouchard +2 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Vocational Rehabilitation for Individuals With Substance-Related Disorders
Objectives: The present review study aimed at investigating the vocational rehabilitation of individuals with drug dependence disorders. Methods: Based on the research method, a comprehensive search was conducted in the following databases: PubMed ...
Younes Doostian +4 more
doaj
Current Concepts on Drug Abuse and Dependence [PDF]
Drug addiction is a complex disease characterized by compulsive and uncontrollable desire to seek and consume the drug. In time, drug-related terminology has undergone many changes, arising from the deepening of the mechanisms of action, but also about ...
Baconi, Daniela Luiza +5 more
core +3 more sources

