Results 91 to 100 of about 2,731,006 (308)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

FARABİ'NİN DÜALİZMİ

open access: yesFelsefe Dünyası, 2008
Eyüp ŞAHİN, "FARABİ'NİN DÜALİZMİ", FELSEFE DÜNYASI DERGİSİ, SAYI ...
Eyüp Şahin
doaj  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Factorial structure and reliability and validity of Turkish Version the Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES) in male alcohol dependent inpatients

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: The Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES), is a 19-item self-rating scale developed by Miller and Tonigan (1996) for screening motivation and readiness to change dirinking - related behavior.
Cüneyt Evren   +2 more
doaj  

Factors associated with drug checking service utilization among people who use drugs in a Canadian setting

open access: yesHarm Reduction Journal, 2020
Background The United States and Canada are amidst an opioid overdose crisis, with the Canadian province of British Columbia (BC) among the hardest hit. In response, drug checking services (DCS) have been introduced in this setting as a novel pilot harm ...
Viseth Long   +9 more
doaj   +1 more source

Assessing Barriers to Mental Health Treatment [PDF]

open access: yes, 2018
It has been well established that individuals with mental illness and substance use disorders face numerous barriers to accessing adequate health care treatment including inability to pay, lack of insurance coverage, lack of provider availability, and ...
Kilgus, Britta J
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Substance, Reality, and Distinctness [PDF]

open access: yes, 2008
Descartes claims that God is a substance and that mind and body are two different and separable substances. This paper provides some background that renders these claims intelligible.
Hennig, Boris
core   +2 more sources

Negative Energy: Why Interdisciplinary Physics Requires Multiple Ontologies

open access: yes, 2013
Much recent work in physics education research has focused on ontological metaphors for energy, particularly the substance ontology and its pedagogical affordances.
Dreyfus, Benjamin W.   +5 more
core   +1 more source

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