Results 181 to 190 of about 2,947,412 (335)

Perfluoroalkyl and Polyfluoroalkyl Substances and Women's Health: A Possible Etiology for Earlier Menopause and Accelerated Reproductive Aging

, 2020
Ning Ding
openalex   +1 more source

Metabolomics within the Framework of Forensic Substance Analysis: Applications, Advances and Perspectives [PDF]

Anton Knieling, Călin Scripcaru, Mădălina Maria Diac, Andreea Alexandra Hlescu, Diana Bulgaru Iliescu, Andrei Scripcaru   +5 more
openalex   +1 more source

Antibiofilm activity of natural substances derived from plants [PDF]

, 2017
Walter Araujo Nogueira Jose, Albuquerque Costa Renata, Turini da Cunha Magda, Thays Arruda Cavalcante Theodora   +3 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Expressive Flexibility as a Buffer in the Association Between Substance Use Stigma and Drug Use Problems Among Substance-Using Individuals with Depression. [PDF]

Stigma Health
Wang K, Girard R, Manning RB, Weiss NH.
europepmc   +1 more source

ANTIDIURETIC SUBSTANCES [PDF]

Journal of Pharmacy and Pharmacology, 1951
openaire   +2 more sources

Does Bacillus larvae produce an antibacterial substance in infected honey bee larvae? [PDF]

, 1992
Z. Gliński, J. Jarosz
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Requiem for Many Dreams? Comorbid Substance Use and Disruptive Behaviour Disorders in Adolescents. [PDF]

Indian J Psychol Med
Ameen S.
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source